Search Results - "JOHSWICH, Kay O"
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In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa
Published in PLoS pathogens (01-07-2013)“…Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances…”
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Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections
Published in Virulence (01-01-2019)“…The complement system is pivotal in the defense against invasive disease caused by Neisseria meningitidis (Nme, meningococcus), particularly via the membrane…”
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Invasive Potential of Nonencapsulated Disease Isolates of Neisseria meningitidis
Published in Infection and Immunity (01-07-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Anticoagulants impact on innate immune responses and bacterial survival in whole blood models of Neisseria meningitidis infection
Published in Scientific reports (05-07-2018)“…Neisseria meningitidis (meningococcus) causes invasive diseases such as meningitis or septicaemia. Ex vivo infection of human whole blood is a valuable tool to…”
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Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment
Published in mBio (23-01-2018)“…Sepsis caused by (meningococcus) is a rapidly progressing, life-threatening disease. Because its initial symptoms are rather unspecific, medical attention is…”
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Differential influences of complement on neutrophil responses to Neisseria meningitidis infection
Published in Pathogens and disease (01-11-2018)“…The complement system is the primary innate immune determinant protecting against invasive diseases caused by the Gram-negative bacterium Neisseria…”
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A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice
Published in Vaccine (10-03-2015)“…Highlights • Human CEACAM1 transgenic mice were immunized with native meningococcal OMV vaccines with attenuated endotoxin and over-expressed FHbp. • The mice…”
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Sterilizing immunity elicited by Neisseria meningitidis carriage shows broader protection than predicted by serum antibody cross-reactivity in CEACAM1-humanized mice
Published in Infection and immunity (01-01-2015)“…Neisseria meningitidis asymptomatically colonizes the human upper respiratory tract but is also the cause of meningitis and severe septicemia. Carriage or…”
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In Vivo Adaptation and Persistence of Neisseria meningitidis within the Nasopharyngeal Mucosa: e1003509
Published in PLoS pathogens (01-07-2013)“…Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances…”
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Complement C5a Receptor 1 Exacerbates the Pathophysiology of italic toggle="yes">N. meningitidis /italic> Sepsis and Is a Potential Target for Disease Treatment
Published in mBio (01-03-2018)“…ABSTRACT Sepsis caused by Neisseria meningitidis (meningococcus) is a rapidly progressing, life-threatening disease. Because its initial symptoms are rather…”
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