Search Results - "JOHNSTON, J. B"

Discrete Aurora at Mars: Insights Into the Role of Magnetic Reconnection by Johnston, B. J., Schneider, N. M., Jain, S. K., Milby, Z., Deighan, J., Bowers, C. F., DiBraccio, G. A., Gérard, J.‐C., Soret, L., Girazian, Z., Brain, D. A., Ruhunusiri, S., Curry, S.

“…Discrete aurora are sporadic emissions of light originating in Mars upper atmosphere. We report nadir imaging observations from MAVEN's Imaging UltraViolet…”
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Increased risk of second malignancies in chronic lymphocytic leukaemia patients as compared with follicular lymphoma patients: a Canadian population-based study by Beiggi, S, Johnston, J B, Seftel, M D, Pitz, M W, Kumar, R, Banerji, V, J Griffith, E, Gibson, S B

“…Background: Chronic lymphocytic leukaemia (CLL) patients have an increased risk of other malignancies. This may be due to surveillance bias, treatment or…”
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Poxvirus immunomodulatory strategies: current perspectives by Johnston, J B, McFadden, Grant

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Myxoma Virus M-T5 Protects Infected Cells from the Stress of Cell Cycle Arrest through Its Interaction with Host Cell Cullin-1 by JOHNSTON, J. B, WANG, G, BARRETT, J. W, NAZARIAN, S. H, COLWILL, K, MORAN, M, MCFADDEN, G

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POXVIRUSES AND IMMUNE EVASION by Seet, Bruce T, Johnston, J.B, Brunetti, Craig R, Barrett, John W, Everett, Helen, Cameron, Cheryl, Sypula, Joanna, Nazarian, Steven H, Lucas, Alexandra, McFadden, Grant

“…Large DNA viruses defend against hostile assault executed by the host immune system by producing an array of gene products that systematically sabotage key…”
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Technical knockout: understanding poxvirus pathogenesis by selectively deleting viral immunomodulatory genes by Johnston, J. B., McFadden, Grant

“…Summary The study of viral pathogens with genomes as large and complex as poxviruses represents a constant experimental challenge. Advances in recombinant DNA…”
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Role of the Serine-Threonine Kinase PAK-1 in Myxoma Virus Replication by Johnston, J B, Barrett, John W, Chang, Wen, Chung, Che-Sheng, Zeng, Wei, Masters, Jennefer, Mann, Melissa, Wang, Fuan, Cao, Jingxin, McFadden, Grant

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Aboriginals with multiple sclerosis : HLA types and predominance of neuromyelitis optica by MIRSATTARI, S. M, JOHNSTON, J. B, MCKENNA, R, DEL BIGIO, M. R, ORR, P, ROSS, R. T, POWER, C

“…MS is common in people of northern European ethnicity who live in northern geographic areas; however, MS is rarely identified among aboriginal peoples living…”
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Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage by Mayne, M, Ni, W, Yan, H J, Xue, M, Johnston, J B, Del Bigio, M R, Peeling, J, Power, C

“…Tumor necrosis factor-alpha (TNF-alpha) expression is increased in brain after cerebral ischemia, although little is known about its abundance and role in…”
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Lentivirus Infection in the Brain Induces Matrix Metalloproteinase Expression: Role of Envelope Diversity by Johnston, J B, Jiang, Y, van Marle, G, Mayne, M B, Ni, W, Holden, J, McArthur, J C, Power, C

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Feline Immunodeficiency Virus Xenoinfection: the Role of Chemokine Receptors and Envelope Diversity by Johnston, J B, Power, C

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Envelope Gene-Mediated Neurovirulence in Feline Immunodeficiency Virus Infection: Induction of Matrix Metalloproteinases and Neuronal Injury by Johnston, J B, Silva, C, Power, C

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Lysosomotropic agents selectively target chronic lymphocytic leukemia cells due to altered sphingolipid metabolism by Dielschneider, R F, Eisenstat, H, Mi, S, Curtis, J M, Xiao, W, Johnston, J B, Gibson, S B

“…Lysosome membrane permeabilization (LMP) mediates cell death in a variety of cancer cells. However, little is known about lysosomes and LMP in chronic…”
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Rapid improvement in symptoms and physical function following ibrutinib initiation in chronic lymphocytic leukemia and the associated changes in plasma cytokines by Ishdorj, G., Nugent, Z., Squires, M., Kost, S., Banerji, V., Davidson, L., Katyal, C.S., Marshall, A., Gibson, S.B., Johnston, J.B.

“…•Significant improvement in fatigue, shortness of breath and a sense of unwellness occurs within 2 weeks of starting ibrutinib in CLL patients.•Ibrutinib…”
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Myxoma virus infection of primary human fibroblasts varies with cellular age and is regulated by host interferon responses by Johnston, J.B., Nazarian, Steven H., Natale, Renato, McFadden, Grant

“…Recent studies have indicated a critical role for interferon (IFN)-mediated antiviral responses in the host range of myxoma virus (MV), a pathogenic poxvirus…”
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Neurovirulence in feline immunodeficiency virus-infected neonatal cats is viral strain specific and dependent on systemic immune suppression by Power, C. (University of Calgary, Calgary, Alberta.), Buist, R, Johnston, J.B, Del Bigio, M.R, Ni, W, Dawood, M.R, Peeling, J

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Descriptive analysis of dosing and outcomes for patients with ibrutinib-treated relapsed or refractory chronic lymphocytic leukemia in a Canadian centre by Uminski, K, Brown, K, Bucher, O, Hibbert, I, Dhaliwal, D H, Johnston, J B, Geirnaert, M, Dawe, D E, Banerji, V

“…Ibrutinib is an approved treatment for relapsed or refractory chronic lymphocytic leukemia (cll) and small lymphocytic lymphoma (sll). The effect of ibrutinib…”
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Relationship between progression-free survival and overall survival in chronic lymphocytic leukemia: a literature-based analysis by Beauchemin, C, Johnston, J B, Lapierre, M È, Aissa, F, Lachaine, J

“…The endpoints of progression-free survival (pfs) and time-to-progression (ttp) are frequently used to evaluate the clinical benefit of anticancer drugs…”
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Infrared spectroscopic study of bryostatin 1-induced membrane alterations in a B-CLL cell line by LIU, K. Z, SCHULTZ, C. P, JOHNSTON, J. B, BECK, F. W. J, AI-KATIB, A. M, MOHAMMAD, R. M, MANTSCH, H. H

“…Previous studies on intact cells have shown that bryostatin 1 (Bryo 1) induces significant alterations in the membranes of WSU-CLL cells (a drug-resistant…”
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Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling by Dielschneider, R F, Xiao, W, Yoon, J-Y, Noh, E, Banerji, V, Li, H, Marshall, A J, Johnston, J B, Gibson, S B

“…Chronic lymphocytic leukemia (CLL) can be divided into groups based on biomarkers of poor prognosis. The expression of the tyrosine kinase ZAP-70 (member of…”
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