Search Results - "JOHNSTON, J. Andrew"

Simvastatin in the Acute Respiratory Distress Syndrome by McAuley, Daniel F, Laffey, John G, O'Kane, Cecilia M, Perkins, Gavin D, Mullan, Brian, Trinder, T. John, Johnston, Paul, Hopkins, Philip A, Johnston, Andrew J, McDowell, Cliona, McNally, Christine

“…In this study, patients with acute respiratory distress syndrome who were not receiving statins were assigned to receive simvastatin or placebo. At 28 days,…”
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A Controlled Trial of Sustained-Release Bupropion, a Nicotine Patch, or Both for Smoking Cessation by Jorenby, Douglas E, Leischow, Scott J, Nides, Mitchell A, Rennard, Stephen I, Johnston, J. Andrew, Hughes, Arlene R, Smith, Stevens S, Muramoto, Myra L, Daughton, David M, Doan, Kimberli, Fiore, Michael C, Baker, Timothy B

“…Each year, approximately 20 million of the 50 million smokers in the United States try to quit smoking, but only about 6 percent of those who try succeed in…”
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Incidence and Mechanisms of Cerebral Ischemia in Early Clinical Head Injury by Coles, Jonathan P., Fryer, Tim D., Smielewski, Piotr, Chatfield, Doris A., Steiner, Luzius A., Johnston, Andrew J., Downey, Stephen P. M. J., Williams, Guy B., Aigbirhio, Franklin, Hutchinson, Peter J., Rice, Kenneth, Carpenter, T. Adrian, Clark, John C., Pickard, John D., Menon, David K.

“…Antemortem demonstration of ischemia has proved elusive in head injury because regional CBF reductions may represent hypoperfusion appropriately coupled to…”
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A Comparison of Sustained-Release Bupropion and Placebo for Smoking Cessation by Hurt, Richard D, Sachs, David P.L, Glover, Penny N, Glover, Elbert D, Offord, Kenneth P, Johnston, J. Andrew, Dale, Lowell C, Khayrallah, Moise A, Schroeder, Darrell R, Sullivan, C. Rollynn, Sullivan, Pamela M, Croghan, Ivana T

“…Pharmacologic treatments such as nicotine-replacement therapy have been shown to help smokers stop smoking. Using a medication that does not contain nicotine,…”
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Incidence and recognition of acute respiratory distress syndrome in a UK intensive care unit by Summers, Charlotte, Singh, Nanak R, Worpole, Linda, Simmonds, Rosalind, Babar, Judith, Condliffe, Alison M, Gunning, Kevin E, Johnston, Andrew J, Chilvers, Edwin R

“…The reported incidence of ARDS is highly variable (2.5%-19% of intensive care unit (ICU) patients) and varies depending on study patient population used. We…”
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Pharmacokinetic optimisation of sustained-release bupropion for smoking cessation by Johnston, Andrew J, Ascher, John, Leadbetter, Robert, Schmith, Virginia D, Patel, Dipak K, Durcan, Michael, Bentley, Beth

“…Sustained-release bupropion (bupropion SR) is a unique, non-nicotine smoking cessation aid that is hypothesised to act upon neurological pathways involved in…”
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Amphipathic Solvation of Indole: Implications for the Role of Tryptophan in Membrane Proteins by Johnston, Andrew J, Zhang, Yapei (Rosie), Busch, Sebastian, Pardo, Luis Carlos, Imberti, Silvia, McLain, Sylvia E

“…The microscopic structure of the tryptophan side chain, indole, in an amphiphilic environment has been investigated using a combination of neutron diffraction…”
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On the atomic structure of cocaine in solution by Johnston, Andrew J, Busch, Sebastian, Pardo, Luis Carlos, Callear, Samantha K, Biggin, Philip C, McLain, Sylvia E

“…Cocaine is an amphiphilic drug which has the ability to cross the blood-brain barrier (BBB). Here, a combination of neutron diffraction and computation has…”
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The Effects of Large-Dose Propofol on Cerebrovascular Pressure Autoregulation in Head-Injured Patients by Steiner, Luzius A., Johnston, Andrew J., Chatfield, Doris A., Czosnyka, Marek, Coleman, Martin R., Coles, Jonathan P., Gupta, Arun K., Pickard, John D., Menon, David K.

“…In healthy individuals, cerebrovascular pressure autoregulation is preserved or even improved when propofol is infused. We examined the effect of an increase…”
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Pharmacokinetics and pharmacodynamics of dopamine and norepinephrine in critically ill head-injured patients by JOHNSTON, Andrew J, STEINER, Luzius A, O'CONNELL, Mark, CHATFIELD, Dot A, GUPTA, Arun K, MENON, David K

“…To explore the pharmacokinetics and pharmacodynamics of dopamine and norepinephrine. Prospective, controlled, trial. Neurosciences critical care unit. Eight…”
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Cardiovascular risks associated with smoking: a review for clinicians by Tonstad, Serena, Andrew Johnston, J

“…The cardiovascular consequences of cigarette smoking may not be as readily recognized as the adverse respiratory consequences. Smoking results in sudden death,…”
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The solvation structure of alprazolam by Sridhar, Akshay, Johnston, Andrew J, Varathan, Luxmmi, McLain, Sylvia E, Biggin, Philip C

“…Alprazolam is a benzodiazepine that is commonly prescribed for the treatment of anxiety and other related disorders. Like other benzodiazepines, it is thought…”
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Extracellular Brain pH and Outcome following Severe Traumatic Brain Injury by Gupta, Arun K, Zygun, David A, Johnston, Andrew J, Steiner, Luzius A, Al-Rawi, Pippa G, Chatfield, Dot, Shepherd, Edna, Kirkpatrick, Peter J, Hutchinson, Peter J, Menon, David K

“…The ability to measure brain tissue chemistry has led to valuable information regarding pathophysiological changes in patients with traumatic brain injury…”
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Late-term smoking cessation despite initial failure: an evaluation of bupropion sustained release, nicotine patch, combination therapy, and placebo by Jamerson, Brenda D., Nides, Mitchell, Jorenby, Douglas E., Donahue, Rafe, Garrett, Peter, Andrew Johnston, J., Fiore, Michael C., Rennard, Stephen I., Leischow, Scott J.

“…Objective: The purpose of this study was to evaluate the efficacy of long-term use of bupropion sustained release (SR), the nicotine patch, and the combination…”
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A double-blind comparison between bupropion XL and venlafaxine XR : Sexual functioning, antidepressant efficacy, and tolerability by THASE, Michael E, CLAYTON, Anita H, HAIGHT, Barbara R, THOMPSON, April H, MODELL, Jack G, JOHNSTON, J. Andrew

“…In this double-blind, multicenter study, bupropion XL, a norepinephrine-dopamine reuptake inhibitor, and venlafaxine XR, a serotonin-norepinephrine reuptake…”
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15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL by Fava, Maurizio, Rush, A John, Thase, Michael E, Clayton, Anita, Stahl, Stephen M, Pradko, James F, Johnston, J Andrew

“…Bupropion has been available in the United States since 1989. Initially a thrice-daily immediate-release formulation, a twice-daily sustained-release…”
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Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury by Johnston, Andrew J, Steiner, Luzius A, Coles, Jonathan P, Chatfield, Doris A, Fryer, Tim D, Smielewski, Peter, Hutchinson, Peter J, O’Connell, Mark T, Al-Rawi, Pippa G, Aigbirihio, Franklin I, Clark, John C, Pickard, John D, Gupta, Arun K, Menon, David K

“…OBJECTIVE:In this study we have used O positron emission tomography, brain tissue oxygen monitoring, and cerebral microdialysis to assess the effects of…”
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Assessment of cerebrovascular autoregulation in head-injured patients: A validation study by STEINER, Luzius A, COLES, Jonathan P, CZOSNYKA, Marek, JOHNSTON, Andrew J, CHATFIELD, Doris A, SMIELEWSKI, Peter, FRYER, Tim D, AIGBIRHIO, Franklin I, CLARK, John C, PICKARD, John D, MENON, David K

“…Cerebrovascular autoregulation is frequently measured in head-injured patients. We attempted to validate 4 bedside methods used for assessment of…”
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Direct comparison of cerebrovascular effects of norepinephrine and dopamine in head-injured patients by Steiner, Luzius A., Johnston, Andrew J., Czosnyka, Marek, Chatfield, Doris A., Salvador, Raymond, Coles, Jonathan P., Gupta, Arun K., Pickard, John D., Menon, David K.

“…To directly compare the cerebrovascular effects of norepinephrine and dopamine in patients with acute traumatic brain injury. Prospective randomized crossover…”
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The Effect of Peripherally Inserted Central Catheter (PICC) Valve Technology on Catheter Occlusion Rates - The ‘ELeCTRiC’ Study by Johnston, Andrew J., Streater, Carmel T., Noorani, Remy, Crofts, Joanne L., Del Mundo, Aldwin B., Parker, Richard A.

“…Purpose Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study…”
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