Search Results - "JOHNSON, M J"

Definitions in hemophilia: communication from the SSC of the ISTH by Blanchette, V. S., Key, N. S., Ljung, L. R., Manco‐Johnson, M. J., Berg, H. M., Srivastava, A.

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Local vibrational coherences drive the primary photochemistry of vision by Johnson, Philip J. M., Halpin, Alexei, Morizumi, Takefumi, Prokhorenko, Valentyn I., Ernst, Oliver P., Miller, R. J. Dwayne

“…The role of vibrational coherence—concerted vibrational motion on the excited-state potential energy surface—in the isomerization of retinal in the protein…”
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Estimating Source Carbon from Crop Residues, Roots and Rhizodeposits Using the National Grain-Yield Database by Johnson, J.M.F, Allmaras, R.R, Reicosky, D.C

“…Crop residue management received little attention until about 1970. Records of crop residue production are limited, but crop yield databases have been…”
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Randomized, controlled, parallel‐group trial of routine prophylaxis vs. on‐demand treatment with sucrose‐formulated recombinant factor VIII in adults with severe hemophilia A (SPINART) by Manco‐Johnson, M. J., Kempton, C. L., Reding, M. T., Lissitchkov, T., Goranov, S., Gercheva, L., Rusen, L., Ghinea, M., Uscatescu, V., Rescia, V., Hong, W.

“…Summary Background The benefits of routine prophylaxis vs. on‐demand treatment with factor VIII products have not been evaluated in controlled clinical trials…”
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Exercise in a hot environment: the skin circulation by Johnson, J. M.

“…The combined metabolic and thermoregulatory demands of exercise in the heat place an exceptional burden on the circulation, more than can be met through…”
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Fibrinogen replacement therapy for congenital fibrinogen deficiency by BORNIKOVA, L., PEYVANDI, F., ALLEN, G., BERNSTEIN, J., MANCO‐JOHNSON, M. J.

“…This review of published studies was conducted to derive data on patients with congenital fibrinogen deficiency (CFD), including dosing of fibrinogen…”
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Effect of late prophylaxis in hemophilia on joint status: a randomized trial by Manco‐Johnson, M. J., Lundin, B., Funk, S., Peterfy, C., Raunig, D., Werk, M., Kempton, C. L., Reding, M. T., Goranov, S., Gercheva, L., Rusen, L., Uscatescu, V., Pierdominici, M., Engelen, S., Pocoski, J., Walker, D., Hong, W.

“…Essentials High‐quality data are lacking on use of prophylaxis in adults with hemophilia and arthropathy. SPINART was a 3‐year randomized clinical trial of…”
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Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography by Wranik, Maximilian, Weinert, Tobias, Slavov, Chavdar, Masini, Tiziana, Furrer, Antonia, Gaillard, Natacha, Gioia, Dario, Ferrarotti, Marco, James, Daniel, Glover, Hannah, Carrillo, Melissa, Kekilli, Demet, Stipp, Robin, Skopintsev, Petr, Brünle, Steffen, Mühlethaler, Tobias, Beale, John, Gashi, Dardan, Nass, Karol, Ozerov, Dmitry, Johnson, Philip J. M., Cirelli, Claudio, Bacellar, Camila, Braun, Markus, Wang, Meitian, Dworkowski, Florian, Milne, Chris, Cavalli, Andrea, Wachtveitl, Josef, Steinmetz, Michel O., Standfuss, Jörg

“…The binding and release of ligands from their protein targets is central to fundamental biological processes as well as to drug discovery. Photopharmacology…”
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Status quo and challenges of rice production in sub-Saharan Africa by Saito, K., Senthilkumar, K., Dossou-Yovo, E. R., Ali, I., Johnson, J-M., Mujawamariya, G., Rodenburg, J.

“…Rice production in sub-Saharan Africa (SSA) has increaed ten-fold since 1961, whereas its consumption has exceeded the production and the regional…”
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Prophylaxis vs. on-demand treatment with Nuwiq® (Human-cl rhFVIII) in adults with severe haemophilia A by Tiede, A., Oldenburg, J., Lissitchkov, T., Knaub, S., Bichler, J., Manco-Johnson, M. J.

“…Introduction Haemophilia A is treated with FVIII, either prophylactically or on demand. Prophylaxis is the gold standard in children and evidence is…”
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Excited-State Vibronic Dynamics of Bacteriorhodopsin from Two-Dimensional Electronic Photon Echo Spectroscopy and Multiconfigurational Quantum Chemistry by Gozem, Samer, Johnson, Philip J. M, Halpin, Alexei, Luk, Hoi Ling, Morizumi, Takefumi, Prokhorenko, Valentyn I, Ernst, Oliver P, Olivucci, Massimo, Miller, R. J. Dwayne

“…Owing to the ultrafast time scale of the photoinduced reaction and high degree of spectral overlap among the reactant, product, and excited electronic states…”
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Azidohomoalanine: A Minimally Invasive, Versatile, and Sensitive Infrared Label in Proteins To Study Ligand Binding by Zanobini, Claudio, Bozovic, Olga, Jankovic, Brankica, Koziol, Klemens L, Johnson, Philip J. M, Hamm, Peter, Gulzar, Adnan, Wolf, Steffen, Stock, Gerhard

“…The noncanonical amino acid azidohomoalanine (Aha) is known to be an environment-sensitive infrared probe for the site-specific investigation of protein…”
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Pharmacokinetics, clot strength and safety of a new fibrinogen concentrate: randomized comparison with active control in congenital fibrinogen deficiency by Ross, C., Rangarajan, S., Karimi, M., Toogeh, G., Apte, S., Lissitchkov, T., Acharya, S., Manco‐Johnson, M. J., Srivastava, A., Brand, B., Schwartz, B. A., Knaub, S., Peyvandi, F.

“…Essentials Congenital afibrinogenemia causes a potentially life‐threatening bleeding and clotting tendency. Two human fibrinogen concentrates (HFCs) were…”
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Protein C deficiency by GOLDENBERG, N. A., MANCO-JOHNSON, M. J.

“…Severe protein C deficiency (i.e. protein C activity <1 IU dL−1) is a rare autosomal recessive disorder that usually presents in the neonatal period with…”
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A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers by Wranik, Maximilian, Kepa, Michal W., Beale, Emma V., James, Daniel, Bertrand, Quentin, Weinert, Tobias, Furrer, Antonia, Glover, Hannah, Gashi, Dardan, Carrillo, Melissa, Kondo, Yasushi, Stipp, Robin T., Khusainov, Georgii, Nass, Karol, Ozerov, Dmitry, Cirelli, Claudio, Johnson, Philip J. M., Dworkowski, Florian, Beale, John H., Stubbs, Scott, Zamofing, Thierry, Schneider, Marco, Krauskopf, Kristina, Gao, Li, Thorn-Seshold, Oliver, Bostedt, Christoph, Bacellar, Camila, Steinmetz, Michel O., Milne, Christopher, Standfuss, Jörg

“…Serial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein…”
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Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia by Li, C, Narkbunnam, N, Samulski, R J, Asokan, A, Hu, G, Jacobson, L J, Manco-Johnson, M J, Monahan, P E

“…Recombinant adeno-associated virus (rAAV) is a promising gene delivery vector and has recently been used in patients with hemophilia. One limitation of AAV…”
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Spin cascade and doming in ferric hemes: Femtosecond X-ray absorption and X-ray emission studies by Bacellar, Camila, Kinschel, Dominik, Mancini, Giulia F., Ingle, Rebecca A., Rouxel, Jérémy, Cannelli, Oliviero, Cirelli, Claudio, Knopp, Gregor, Szlachetko, Jakub, Lima, Frederico A., Menzi, Samuel, Pamfilidis, Georgios, Kubicek, Katharina, Khakhulin, Dmitry, Gawelda, Wojciech, Rodriguez-Fernandez, Angel, Biednov, Mykola, Bressler, Christian, Arrell, Christopher A., Johnson, Philip J. M., Milne, Christopher J., Chergui, Majed

“…The structure–function relationship is at the heart of biology, and major protein deformations are correlated to specific functions. For ferrous heme proteins,…”
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Fast infrared spectroscopy of protein dynamics: advancing sensitivity and selectivity by Koziol, Klemens L, Johnson, Philip JM, Stucki-Buchli, Brigitte, Waldauer, Steven A, Hamm, Peter

“…•The untapped potential of 2D-IR spectroscopy lies in its high direct time resolution.•The major limitation of 2D-IR spectroscopy for larger proteins is…”
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Prompt immune tolerance induction at inhibitor diagnosis regardless of titre may increase overall success in haemophilia A complicated by inhibitors: experience of two US centres by Nakar, C., Manco-Johnson, M. J., Lail, A., Donfield, S., Maahs, J., Chong, Y., Blades, T., Shapiro, A.

“…Summary Current guidelines recommend delaying the start of immune tolerance induction (ITI) until the inhibitor titre is <10 Bethesda units (BU) to improve…”
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Development of a core outcome set for trials on induction of labour: an international multistakeholder Delphi study by Dos Santos, F, Drymiotou, S, Antequera Martin, A, Mol, BW, Gale, C, Devane, D, Hooft, J, Johnson, MJ, Hogg, M, Thangaratinam, S

“…Objective To develop a set of core outcomes to be minimally reported in trials on induction of labour. Design Two‐round Delphi survey and consensus meeting…”
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