Search Results - "JOHNSON, Julie"
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Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update
Published in Clinical pharmacology and therapeutics (01-11-2022)“…CYP2C19 catalyzes the bioactivation of the antiplatelet prodrug clopidogrel, and CYP2C19 genotype impacts clopidogrel active metabolite formation. CYP2C19…”
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Cannabis Research and Therapeutics: An International Quasi-experiment in Cannabis Policy
Published in Clinical therapeutics (01-06-2023)Get full text
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Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine
Published in Expert opinion on drug metabolism & toxicology (03-04-2018)“…Proton Pump inhibitors (PPIs) are commonly used for a variety of acid related disorders. Despite the overall effectiveness and safety profile of PPIs, some…”
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Ethnic Differences in Cardiovascular Drug Response : Potential Contribution of Pharmacogenetics
Published in Circulation (New York, N.Y.) (23-09-2008)Get full text
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History of Cannabis Regulation and Medicinal Therapeutics: It's Complicated
Published in Clinical therapeutics (01-06-2023)“…The genus Cannabis has a complex history, with great variations in the genus itself, as well as in its current uses worldwide. Today, it is the most commonly…”
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Association Between Surgeon Technical Skills and Patient Outcomes
Published in JAMA surgery (01-10-2020)“…Postoperative complications remain common after surgery, but little is known about the extent of variation in operative technical skill and whether variation…”
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Warfarin pharmacogenetics: a rising tide for its clinical value
Published in Circulation (New York, N.Y.) (24-04-2012)Get full text
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A Point-of-Care Resource to Improve Care of Patients with Adrenal Mass: www.AdrenalMass.org
Published in European urology (01-04-2022)Get full text
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CYP2D6 pharmacogenetics and phenoconversion in personalized medicine
Published in Expert opinion on drug metabolism & toxicology (02-11-2022)“…CYP2D6 contributes to the metabolism of approximately 20-25% of drugs. However, is highly polymorphic and different alleles can lead to impacts ranging from…”
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing
Published in Clinical pharmacology and therapeutics (01-06-2021)“…Proton pump inhibitors (PPIs) are widely used for acid suppression in the treatment and prevention of many conditions, including gastroesophageal reflux…”
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Warfarin pharmacogenetics
Published in Trends in cardiovascular medicine (01-01-2015)“…Abstract The cytochrome P450 (CYP) 2C9 and vitamin K epoxide reductase complex 1 (VKORC1) genotypes have been strongly and consistently associated with…”
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Short-term effects of ambient air pollution on stroke: Who is most vulnerable?
Published in The Science of the total environment (15-07-2012)“…Several studies have demonstrated positive associations between day-to-day increases in air pollution and stroke. These findings have been inconsistent, and…”
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Elucidating the Impact of Adolescent Marijuana Use
Published in Journal of adolescent health (01-08-2018)Get full text
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Tribute to Professor Hartmut Derendorf ‐ 1953 to 2020: Driving force in Clinical Pharmacology and Mentor Extraordinaire
Published in Clinical pharmacology and therapeutics (01-04-2021)Get full text
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Past 30–Day Marijuana Vaping: Prevalence and Predictors of Use in a Nationally Representative Study of U.S. Youth
Published in American journal of preventive medicine (01-02-2021)“…Vaping has become an increasingly common mode of administration for marijuana among youth, but there are limited data on its prevalence. There is a need to…”
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Pharmacogenetics and cardiovascular disease--implications for personalized medicine
Published in Pharmacological reviews (01-07-2013)“…The past decade has seen tremendous advances in our understanding of the genetic factors influencing response to a variety of drugs, including those targeted…”
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Pharmacogenetics in clinical practice: how far have we come and where are we going?
Published in Pharmacogenomics (01-05-2013)“…Recent years have seen great advances in our understanding of genetic contributors to drug response. Drug discovery and development around targeted genetic…”
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Gender Differences in Utilization of Duty-hour Regulations, Aspects of Burnout, and Psychological Well-being Among General Surgery Residents in the United States
Published in Annals of surgery (01-08-2018)“…OBJECTIVE:The aim of the study was to (1) assess differences in how male and female general surgery residents utilize duty-hour regulations and experience…”
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Pharmacogenetic factors affecting β-blocker metabolism and response
Published in Expert opinion on drug metabolism & toxicology (02-10-2020)“…β-blockers are among the most widely prescribed of all drugs, used for treatment of a large number of cardiovascular diseases. Herein we evaluate literature…”
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Hypertension pharmacogenomics: in search of personalized treatment approaches
Published in Nature reviews. Nephrology (01-02-2016)“…Key Points Hypertension is an important, modifiable risk factor for cardiovascular and kidney disease Rates of blood pressure control are substantially below…”
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