Search Results - "JOHNSON, ANDREW"

The Origins and Drivers of Insulin Resistance by Johnson, Andrew M.F., Olefsky, Jerrold M.

“…Obesity-induced insulin resistance is the major determinant of metabolic syndrome, which precedes the development of type 2 diabetes mellitus and is thus the…”
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Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance by Li, Pingping, Liu, Shuainan, Lu, Min, Bandyopadhyay, Gautum, Oh, Dayoung, Imamura, Takeshi, Johnson, Andrew M.F., Sears, Dorothy, Shen, Zhufang, Cui, Bing, Kong, Lijuan, Hou, Shaocong, Liang, Xiao, Iovino, Salvatore, Watkins, Steven M., Ying, Wei, Osborn, Olivia, Wollam, Joshua, Brenner, Martin, Olefsky, Jerrold M.

“…In obesity, macrophages and other immune cells accumulate in insulin target tissues, promoting a chronic inflammatory state and insulin resistance. Galectin-3…”
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Cell perturbation and lasers illuminate the genetics of latent blood cell traits by Johnson, Andrew D.

“…A new study combining experimental treatments of human blood cells from thousands of individuals with flow-cytometry-based phenotyping and then genome-wide…”
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Generative AI, UK Copyright and Open Licences: considerations for UK HEI copyright advice services [version 1; peer review: awaiting peer review] by Johnson, Andrew

“…With the enormous growth in interest and use of generative artificial intelligence (AI) systems seen since the launch of ChatGPT in autumn 2022 have come…”
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Learning from the past and considering the future of chemicals in the environment by Johnson, Andrew C, Jin, Xiaowei, Nakada, Norihide, Sumpter, John P

“…Knowledge of the hazards and associated risks from chemicals discharged to the environment has grown considerably over the past 40 years. This improving…”
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High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability by Johnson, Andrew M F, Costanzo, Anne, Gareau, Melanie G, Armando, Aaron M, Quehenberger, Oswald, Jameson, Julie M, Olefsky, Jerrold M

“…The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However,…”
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A Tiered Model for Data Management, Curation, and Sharing Support in Grant Proposals and Budgets by Johnson, Andrew

“…Recent trends in research funder policies and guidelines increasingly point to requirements for more detailed plans for data management, curation, and sharing…”
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COVID‐19 vulnerabilities are intensified by declining human serum albumin levels by Johnson, Andrew S., Winlow, William

“…What is the topic of this review? Human serum albumin (HSA) a common factor in COVID‐19 vulnerabilities. What advances does it highlight? Understanding of HSA…”
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Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease by Börgeson, Emma, Johnson, Andrew M.F., Lee, Yun Sok, Till, Andreas, Syed, Gulam Hussain, Ali-Shah, Syed Tasadaque, Guiry, Patrick J., Dalli, Jesmond, Colas, Romain A., Serhan, Charles N., Sharma, Kumar, Godson, Catherine

“…The role of inflammation in obesity-related pathologies is well established. We investigated the therapeutic potential of LipoxinA4…”
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70-year legacy of the Framingham Heart Study by Andersson, Charlotte, Johnson, Andrew D., Benjamin, Emelia J., Levy, Daniel, Vasan, Ramachandran S.

“…The Framingham Heart Study (FHS) was established in 1948 to improve understanding of the epidemiology of coronary heart disease (CHD) in the USA. In 1961,…”
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Ecological risk assessment of fifty pharmaceuticals and personal care products (PPCPs) in Chinese surface waters: A proposed multiple-level system by Liu, Na, Jin, Xiaowei, Feng, Chenglian, Wang, Zijian, Wu, Fengchang, Johnson, Andrew C., Xiao, Hongxia, Hollert, Henner, Giesy, John P.

“…•A multiple-level system was proposed for risk rank of PPCPs in waters.•12 PPCPs showed environmental risks in Chinese surface waters.•Detected frequency,…”
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GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database by Leslie, Richard, O'Donnell, Christopher J, Johnson, Andrew D

“…We created a deeply extracted and annotated database of genome-wide association studies (GWAS) results. GRASP v1.0 contains >6.2 million SNP-phenotype…”
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GPR43 Potentiates β-Cell Function in Obesity by McNelis, Joanne C, Lee, Yun Sok, Mayoral, Rafael, van der Kant, Rik, Johnson, Andrew M F, Wollam, Joshua, Olefsky, Jerrold M

“…The intestinal microbiome can regulate host energy homeostasis and the development of metabolic disease. Here we identify GPR43, a receptor for bacterially…”
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Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers by Johnson, Andrew C, Keller, Virginie, Dumont, Egon, Sumpter, John P

“…This study evaluated the potential concentrations of four antibiotics: ciprofloxacin (CIP), sulfamethoxazole (SUF), trimethoprim (TRI) and erythromycin (ERY)…”
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An open access database of genome-wide association results by Johnson, Andrew D, O'Donnell, Christopher J

“…The number of genome-wide association studies (GWAS) is growing rapidly leading to the discovery and replication of many new disease loci. Combining results…”
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One-stage and two-stage DEA estimation of the effects of contextual variables by Johnson, Andrew L., Kuosmanen, Timo

“…► In two-stage DEA (2-DEA) efficiency estimates are regressed on contextual variables. ► We show that 2-DEA is consistent under more general conditions than…”
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Collision-Induced Dissociation Mass Spectrometry: A Powerful Tool for Natural Product Structure Elucidation by Johnson, Andrew R, Carlson, Erin E

“…Mass spectrometry is a powerful tool in natural product structure elucidation, but our ability to directly correlate fragmentation spectra to these structures…”
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Multiple crop bioaccumulation and human exposure of perfluoroalkyl substances around a mega fluorochemical industrial park, China: Implication for planting optimization and food safety by Liu, Zhaoyang, Lu, Yonglong, Song, Xin, Jones, Kevin, Sweetman, Andrew J., Johnson, Andrew C., Zhang, Meng, Lu, Xiaotian, Su, Chao

“…Perfluoroalkyl substances (PFASs) have become a recognized concern due to their mobility, persistence, ubiquity and health hazards in the environment. In this…”
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Sources of variability in the human platelet transcriptome by Thibord, Florian, Johnson, Andrew D.

“…Platelets are anucleated cells produced by megakaryocytes, from which they inherit all the components necessary to carry their functions. They circulate in…”
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Collecting and preserving bark and ambrosia beetles (Coleoptera: Curculionidae: Scolytinae & Platypodinae) by Hulcr, Jiri, Gomez, Demian F, Johnson, Andrew J

“…This protocol describes the different methods to collect and preserve bark and ambrosia beetles, detailing collecting tools, recording relevant data, and…”
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