Search Results - "JINYANG ZENG"
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1
Age-specific effects on adverse pregnancy outcomes vary by maternal characteristics: a population-based retrospective study in Xiamen, China
Published in BMC public health (14-02-2023)“…Advanced maternal age (AMA; ≥35 years) is considered to be a major risk factor for adverse pregnancy outcomes. Along with the global trend of delayed…”
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2
Clinical analysis of the etiological spectrum of bilateral adrenal lesions: A large retrospective, single-center study
Published in Endocrine (01-08-2022)“…Purpose To investigate the clinical characteristics, endocrinological function, and etiology of bilateral adrenal lesions in hospitalized patients. Methods A…”
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3
Primary Adrenal Lymphoma: Two Case Series From China
Published in Frontiers in endocrinology (Lausanne) (28-01-2022)“…Primary adrenal lymphoma (PAL) is a rare form of adrenal mass. We summarize our experience in its clinical presentation, biochemical indexes, radiological…”
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4
Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults
Published in BMC gastroenterology (18-11-2021)“…Purpose The aim of the study is to explore the independent association of free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone…”
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5
Higher Apnea-Hypopnea Index (AHI) and Oxygen Desaturation Index (ODI) Were Independently Associated with Increased Risks of Hypertension in Patients with T2DM: A Cross-Sectional Study
Published in International journal of hypertension (2021)“…Objective. The current study aimed to explore the relationship between OSAS and hypertension and whether polysomnography (PSG) indices were independently…”
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6
Biglycan is a new high-affinity ligand for CD14 in macrophages
Published in Matrix biology (01-04-2019)“…Sterile inflammation is a therapeutic target in many diseases where it represents an important initiator of disease progression. However, the detailed…”
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7
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21
Published in Science signaling (15-11-2011)“…The mechanisms linking immune responses and inflammation with tumor development are not well understood. Here, we show that the soluble form of the…”
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8
Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors
Published in The Journal of biological chemistry (04-09-2009)“…The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1β, macrophages need…”
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9
Independent Association of Serum Fibroblast Growth Factor 21 Levels With Impaired Liver Enzymes in Hyperthyroid Patients
Published in Frontiers in endocrinology (Lausanne) (14-01-2019)“…Fibroblast growth factor 21 (FGF21) is identified as a potential biomarker for liver diseases. However, information is limited regarding serum FGF21 and…”
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10
Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury
Published in Matrix biology (01-04-2014)“…Exacerbated inflammation in renal ischemia–reperfusion injury, the major cause of intrinsic acute renal failure, is a key trigger of kidney damage. During…”
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11
Effect of exenatide after short-time intensive insulin therapy on glycaemic remission maintenance in type 2 diabetes patients: a randomized controlled trial
Published in Scientific reports (24-05-2017)“…Early short-term intensive insulin (STII) therapy can induce drug-free glycemic remission for up to 1 year in half of newly diagnosed type 2 diabetic mellitus…”
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12
Soluble biglycan as a biomarker of inflammatory renal diseases
Published in The international journal of biochemistry & cell biology (01-09-2014)“…Chronic renal inflammation is often associated with a progressive accumulation of various extracellular matrix constituents, including several members of the…”
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13
The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis
Published in The Journal of clinical investigation (01-12-2010)“…CXCL13 is a key B cell chemoattractant and marker of disease activity in patients with SLE; however, the mechanism of its induction has not been identified…”
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14
De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways
Published in Matrix biology (01-04-2014)“…Matrix-bound constituents, such as the small leucine-rich proteoglycan biglycan, can act as powerful signaling molecules when released by limited proteolysis…”
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15
Resistance to thyroid hormone caused by heterozygous mutation of thyroid hormone receptor B gene c.G1378A: Report of one Chinese pedigree and literature review
Published in Clinical case reports (01-03-2021)“…The same thyroid hormone receptor B gene (THRB) mutation led to thyroid hormone resistance with different clinical manifestations in the kindreds. The same…”
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16
Biglycan regulates bone development and regeneration
Published in Frontiers in physiology (16-02-2023)“…Endochondral bone development and regeneration relies on activation and proliferation of periosteum derived-cells (PDCs). Biglycan (Bgn), a small proteoglycan…”
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17
An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis
Published in The American journal of pathology (01-05-2016)“…Sepsis is burdened by high mortality due to uncontrolled inflammatory response to pathogens. Increased caspase 1 activation causing maturation of IL1β/18…”
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18
Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants
Published in International journal of molecular sciences (09-03-2017)“…In its soluble form, the extracellular matrix proteoglycan biglycan triggers the synthesis of the macrophage chemoattractants, chemokine (C-C motif) ligand…”
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19
A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia
Published in Glycoconjugate journal (01-06-2017)“…Secondary polycythemia, a disease characterized by a selective increase in circulating mature erythrocytes, is caused by enhanced erythropoietin (Epo)…”
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20
Two ways to induce innate immune responses in human PBMCs: paracrine stimulation of IFN-alpha responses by viral protein or dsRNA
Published in International journal of oncology (01-09-2003)“…In order to study mechanisms of induction of IFN-alpha by Newcastle disease virus (NDV), we used two replicon systems which are based respectively on DNA and…”
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