Search Results - "JIMENEZ, Wladimiro"

Relative adrenal insufficiency in decompensated cirrhosis: Relationship to short‐term risk of severe sepsis, hepatorenal syndrome, and death by Acevedo, Juan, Fernández, Javier, Prado, Verónica, Silva, Anibal, Castro, Miriam, Pavesi, Marco, Roca, Daria, Jimenez, Wladimiro, Ginès, Pere, Arroyo, Vicente

“…The prevalence of relative adrenal insufficiency (RAI) in critically ill cirrhosis patients with severe sepsis is over 60% and associated features include poor…”
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Apelin Mediates the Induction of Profibrogenic Genes in Human Hepatic Stellate Cells by Melgar-Lesmes, Pedro, Casals, Gregori, Pauta, Montserrat, Ros, Josefa, Reichenbach, Vedrana, Bataller, Ramon, Morales-Ruiz, Manuel, Jimenez, Wladimiro

“…Apelin is a peptide with relevant functions in angiogenesis and inflammation. Recent studies have demonstrated that apelin is overexpressed in hepatic stellate…”
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Pituitary Tumor-Transforming Gene 1/Delta like Non-Canonical Notch Ligand 1 Signaling in Chronic Liver Diseases by Perramón, Meritxell, Jiménez, Wladimiro

“…The management of chronic liver diseases (CLDs) remains a challenge, and identifying effective treatments is a major unmet medical need. In the current review…”
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Graphene–Dendrimer Nanostars for Targeted Macrophage Overexpression of Metalloproteinase 9 and Hepatic Fibrosis Precision Therapy by Melgar-Lesmes, Pedro, Luquero, Aureli, Parra-Robert, Marina, Mora, Adriana, Ribera, Jordi, Edelman, Elazer R, Jiménez, Wladimiro

“…Fibrosis contributes to ∼45% of all deaths in industrialized nations, but no direct antifibrotic therapeutic interventions exist to date. Graphene-based…”
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Treatment of Hepatic Fibrosis in Mice Based on Targeted Plasmonic Hyperthermia by Ribera, Jordi, Vilches, Clara, Sanz, Vanesa, de Miguel, Ignacio, Portolés, Irene, Córdoba-Jover, Bernat, Prat, Esther, Nunes, Virginia, Jiménez, Wladimiro, Quidant, Romain, Morales-Ruiz, Manuel

“…Liver fibrosis is a major health problem with multiple associated complications, which, to date, has no effective treatment. Hepatic stellate cells are the…”
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Biopsia líquida: un reto para el laboratorio de diagnóstico clínico by Jiménez, Wladimiro

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Analysis of a urinary biomarker panel for clinical outcomes assessment in cirrhosis by Ariza, Xavier, Solà, Elsa, Elia, Chiara, Barreto, Rogelio, Moreira, Rebeca, Morales-Ruiz, Manuel, Graupera, Isabel, Rodríguez, Ezequiel, Huelin, Patricia, Solé, Cristina, Fernández, Javier, Jiménez, Wladimiro, Arroyo, Vicente, Ginès, Pere

“…Biomarkers are potentially useful in assessment of outcomes in patients with cirrhosis, but information is very limited. Given the large number of biomarkers,…”
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Monocyte-endothelial cell interactions in vascular and tissue remodeling by Medrano-Bosch, Mireia, Simón-Codina, Blanca, Jiménez, Wladimiro, Edelman, Elazer R, Melgar-Lesmes, Pedro

“…Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or…”
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Cerium Oxide Nanoparticles: Advances in Biodistribution, Toxicity, and Preclinical Exploration by Casals, Eudald, Zeng, Muling, Parra‐Robert, Marina, Fernández‐Varo, Guillermo, Morales‐Ruiz, Manuel, Jiménez, Wladimiro, Puntes, Víctor, Casals, Gregori

“…Antioxidant nanoparticles have recently gained tremendous attention for their enormous potential in biomedicine. However, discrepant reports of either medical…”
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Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis by Solé, Cristina, Solà, Elsa, Morales-Ruiz, Manuel, Fernàndez, Guerau, Huelin, Patricia, Graupera, Isabel, Moreira, Rebeca, de Prada, Gloria, Ariza, Xavier, Pose, Elisa, Fabrellas, Núria, Kalko, Susana G., Jiménez, Wladimiro, Ginès, Pere

“…ACLF is characterized by a systemic inflammatory response, but the cytokines involved in this process have not been well studied. The aim of this study was to…”
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Neutrophil Gelatinase‐Associated Lipocalin for Assessment of Acute Kidney Injury in Cirrhosis: A Prospective Study by Huelin, Patricia, Solà, Elsa, Elia, Chiara, Solé, Cristina, Risso, Alessandro, Moreira, Rebeca, Carol, Marta, Fabrellas, Núria, Bassegoda, Octavi, Juanola, Adrià, de Prada, Gloria, Albertos, Sonia, Piano, Salvatore, Graupera, Isabel, Ariza, Xavier, Napoleone, Laura, Pose, Elisa, Filella, Xavier, Morales‐Ruiz, Manuel, Rios, José, Fernández, Javier, Jiménez, Wladimiro, Poch, Esteban, Torres, Ferran, Ginès, Pere

“…Kidney biomarkers appear to be useful in differential diagnosis between acute tubular necrosis (ATN) and other types of acute kidney injury (AKI) in cirrhosis,…”
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Cerium oxide nanoparticles reduce steatosis, portal hypertension and display anti-inflammatory properties in rats with liver fibrosis by Oró, Denise, Yudina, Tetyana, Fernández-Varo, Guillermo, Casals, Eudald, Reichenbach, Vedrana, Casals, Gregori, González de la Presa, Bernardino, Sandalinas, Silvia, Carvajal, Silvia, Puntes, Victor, Jiménez, Wladimiro

“…Graphical abstract…”
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Roles of the Hepatic Endocannabinoid and Apelin Systems in the Pathogenesis of Liver Fibrosis by Melgar-Lesmes, Pedro, Perramon, Meritxell, Jiménez, Wladimiro

“…Hepatic fibrosis is the consequence of an unresolved wound healing process in response to chronic liver injury and involves multiple cell types and molecular…”
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Partial vasopressin 1a receptor agonism reduces portal hypertension and hyperaldosteronism and induces a powerful diuretic and natriuretic effect in rats with cirrhosis and ascites by Fernández-Varo, Guillermo, Jiménez, Wladimiro, Cable, Edward, Ginès, Pere, Harris, Geoff, Bukofzer, Stan

“…The vasopressin system has emerged as a therapeutic focus for lowering portal hypertension and reducing splanchnic vasodilation in patients with refractory…”
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The Role of Akt in Chronic Liver Disease and Liver Regeneration by Morales-Ruiz, Manuel, Santel, Ansgar, Ribera, Jordi, Jiménez, Wladimiro

“…The liver is continuously exposed to diverse insults, which may culminate in pathological processes causing liver disease. An effective therapeutic strategy…”
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Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients by Soto, Marcelo, Sampietro-Colom, Laura, Lasalvia, Luis, Mira, Aurea, Jiménez, Wladimiro, Navasa, Miquel

“…AIM To assess liver fibrosis(LF) in hepatitis C virus(HCV) and alcoholic liver disease(ALD), estimate health outcomes and costs of new noninvasive testing…”
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RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration by Moreno-Lanceta, Alazne, Medrano-Bosch, Mireia, Fundora, Yilliam, Perramón, Meritxell, Aspas, Jessica, Parra-Robert, Marina, Baena, Sheila, Fondevila, Constantino, Edelman, Elazer R, Jiménez, Wladimiro, Melgar-Lesmes, Pedro

“…Hepatic inflammation is a common trigger of chronic liver disease. Macrophage activation is a predictive parameter for survival in patients with cirrhosis…”
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Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats by Córdoba-Jover, Bernat, Arce-Cerezo, Altamira, Ribera, Jordi, Pauta, Montse, Oró, Denise, Casals, Gregori, Fernández-Varo, Guillermo, Casals, Eudald, Puntes, Victor, Jiménez, Wladimiro, Morales-Ruiz, Manuel

“…Cerium oxide nanoparticles are effective scavengers of reactive oxygen species and have been proposed as a treatment for oxidative stress-related diseases…”
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Intrinsic and Extrinsic Properties Affecting Innate Immune Responses to Nanoparticles: The Case of Cerium Oxide by Casals, Eudald, Gusta, Muriel F, Piella, Jordi, Casals, Gregori, Jiménez, Wladimiro, Puntes, Victor

“…We review the apparent discrepancies between studies that report anti-inflammatory effects of cerium oxide nanoparticles (CeO NPs) through their reactive…”
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ARFI, FibroScan®, ELF, and their combinations in the assessment of liver fibrosis: A prospective study by Crespo, Gonzalo, Fernández-Varo, Guillermo, Mariño, Zoe, Casals, Gregori, Miquel, Rosa, Martínez, Stella M, Gilabert, Rosa, Forns, Xavier, Jiménez, Wladimiro, Navasa, Miquel

“…Background & Aims Our aim was to evaluate a serologic marker (ELF) and two ultrasound-based methods (FibroScan® and ARFI), as well as their combinations, in…”
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