Search Results - "JIANMING HU"
-
1
Complete and Incomplete Hepatitis B Virus Particles: Formation, Function, and Application
Published in Viruses (21-03-2017)“…Hepatitis B virus (HBV) is a para-retrovirus or retroid virus that contains a double-stranded DNA genome and replicates this DNA via reverse transcription of a…”
Get full text
Journal Article -
2
A robust combination approach for short-term wind speed forecasting and analysis – Combination of the ARIMA (Autoregressive Integrated Moving Average), ELM (Extreme Learning Machine), SVM (Support Vector Machine) and LSSVM (Least Square SVM) forecasts using a GPR (Gaussian Process Regression) model
Published in Energy (Oxford) (01-12-2015)“…With the increasing importance of wind power as a component of power systems, the problems induced by the stochastic and intermittent nature of wind speed have…”
Get full text
Journal Article -
3
Revisiting Hepatitis B Virus: Challenges of Curative Therapies
Published in Journal of virology (15-10-2019)“…With a yearly death toll of 880,000, hepatitis B virus (HBV) remains a major health problem worldwide, despite an effective prophylactic vaccine and…”
Get full text
Journal Article -
4
PPCA-Based Missing Data Imputation for Traffic Flow Volume: A Systematical Approach
Published in IEEE transactions on intelligent transportation systems (01-09-2009)“…The missing data problem greatly affects traffic analysis. In this paper, we put forward a new reliable method called probabilistic principal component…”
Get full text
Journal Article -
5
Harmonious Lane Changing via Deep Reinforcement Learning
Published in IEEE transactions on intelligent transportation systems (01-05-2022)“…In this paper, we study how to learn a harmonious deep reinforcement learning (DRL) based lane-changing strategy for autonomous vehicles without…”
Get full text
Journal Article -
6
A hybrid forecasting approach applied to wind speed time series
Published in Renewable energy (01-12-2013)“…In this paper, a hybrid forecasting approach, which combines the Ensemble Empirical Mode Decomposition (EEMD) and the Support Vector Machine (SVM), is proposed…”
Get full text
Journal Article -
7
Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation
Published in PLoS pathogens (30-03-2020)“…Hepatitis B virus (HBV) delivers a partially double-stranded, relaxed circular (RC) DNA genome in complete virions to the host cell nucleus for conversion to…”
Get full text
Journal Article -
8
Identification of an Intermediate in Hepatitis B Virus Covalently Closed Circular (CCC) DNA Formation and Sensitive and Selective CCC DNA Detection
Published in Journal of virology (01-09-2017)“…Hepatitis B virus (HBV) covalently closed circular (CCC) DNA functions as the only viral template capable of coding for all the viral RNA species and is thus…”
Get full text
Journal Article -
9
Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes
Published in PLoS pathogens (28-07-2022)“…Hepadnaviruses use extensively overlapping genes to expand their coding capacity, especially the precore/core genes encode the precore and core proteins with…”
Get full text
Journal Article -
10
Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication
Published in PLoS pathogens (25-01-2021)“…Hepatitis B virus (HBV) capsid or core protein (HBc) contains an N-terminal domain (NTD) and a C-terminal domain (CTD) connected by a short linker peptide. HBc…”
Get full text
Journal Article -
11
Host cell-dependent late entry step as determinant of hepatitis B virus infection
Published in PLoS pathogens (01-06-2022)“…Hepatitis B virus (HBV) has a highly restricted host range and cell tropism. Other than the human sodium taurocholate cotransporting polypeptide (huNTCP), the…”
Get full text
Journal Article -
12
Pattern of distant metastases in colorectal cancer: a SEER based study
Published in Oncotarget (17-11-2015)“…More and more evidences suggest that primary colon and rectum tumors should not be considered as a single disease entity. In this manuscript, we evaluate the…”
Get full text
Journal Article -
13
Hepatitis B virus reverse transcriptase – Target of current antiviral therapy and future drug development
Published in Antiviral research (01-11-2015)“…•The HBV RT, unique in its function as a protein primer for DNA synthesis, is the main target of current antiviral therapy.•Recently developed experimental…”
Get full text
Journal Article -
14
Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein
Published in Journal of Virology (01-06-2007)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
15
Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2019)“…Many cell culture and animal models have been used to study hepatitis B virus (HBV) replication and its effects in the liver; these have facilitated…”
Get full text
Journal Article -
16
Common and Distinct Capsid and Surface Protein Requirements for Secretion of Complete and Genome-Free Hepatitis B Virions
Published in Journal of virology (15-07-2018)“…During the morphogenesis of hepatitis B virus (HBV), an enveloped virus, two types of virions are secreted: (i) a minor population of complete virions…”
Get full text
Journal Article -
17
CoSe2 Nanowires Array as a 3D Electrode for Highly Efficient Electrochemical Hydrogen Evolution
Published in ACS applied materials & interfaces (25-02-2015)“…In this Letter, we describe the development of a CoSe2 nanowires array on carbon cloth (CoSe2 NW/CC) through a facile two-step hydrothermal preparative…”
Get full text
Journal Article -
18
Multiple roles of core protein linker in hepatitis B virus replication
Published in PLoS pathogens (01-05-2018)“…Hepatitis B virus (HBV) core protein (HBc) contains an N-terminal domain (NTD, assembly domain) and a C-terminal domain (CTD), which are linked by a flexible…”
Get full text
Journal Article -
19
Alteration of Mature Nucleocapsid and Enhancement of Covalently Closed Circular DNA Formation by Hepatitis B Virus Core Mutants Defective in Complete-Virion Formation
Published in Journal of virology (01-10-2015)“…Assembly of hepatitis B virus (HBV) begins with packaging of the pregenomic RNA (pgRNA) into immature nucleocapsids (NC), which are converted to mature NCs…”
Get full text
Journal Article -
20
A computational spatial whole-Cell model for hepatitis B viral infection and drug interactions
Published in Scientific reports (04-12-2023)“…Despite a vaccine, hepatitis B virus (HBV) remains a world-wide source of infections and deaths. We develop a whole-cell computational platform combining…”
Get full text
Journal Article