Search Results - "JIANG, DEYUAN"

Sofosbuvir for Previously Untreated Chronic Hepatitis C Infection by Lawitz, Eric, Mangia, Alessandra, Wyles, David, Rodriguez-Torres, Maribel, Hassanein, Tarek, Gordon, Stuart C, Schultz, Michael, Davis, Mitchell N, Kayali, Zeid, Reddy, K. Rajender, Jacobson, Ira M, Kowdley, Kris V, Nyberg, Lisa, Subramanian, G. Mani, Hyland, Robert H, Arterburn, Sarah, Jiang, Deyuan, McNally, John, Brainard, Diana, Symonds, William T, McHutchison, John G, Sheikh, Aasim M, Younossi, Zobair, Gane, Edward J

“…In two studies of sofosbuvir for previously untreated HCV infection, patients with genotype 1, 4, 5, or 6 had a 90% rate of sustained virologic response in a…”
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Mitochondrial Transcription Termination Factor 27 Is Required for Salt Tolerance in Arabidopsis thaliana by Jiang, Deyuan, Chen, Jian, Zhang, Zhihong, Hou, Xin

“…In plants, mTERF proteins are primarily found in mitochondria and chloroplasts. Studies have identified several mTERF proteins that affect plant development,…”
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Ledipasvir-sofosbuvir with or without ribavirin to treat patients with HCV genotype 1 infection and cirrhosis non-responsive to previous protease-inhibitor therapy: a randomised, double-blind, phase 2 trial (SIRIUS) by Bourlière, Marc, Dr, Bronowicki, Jean-Pierre, MD, de Ledinghen, Victor, MD, Hézode, Christophe, MD, Zoulim, Fabien, MD, Mathurin, Philippe, MD, Tran, Albert, MD, Larrey, Dominique G, MD, Ratziu, Vlad, MD, Alric, Laurent, MD, Hyland, Robert H, DPhil, Jiang, Deyuan, PhD, Doehle, Brian, PhD, Pang, Phillip S, MD, Symonds, William T, PharmD, Subramanian, G Mani, MD, McHutchison, John G, MD, Marcellin, Patrick, MD, Habersetzer, François, MD, Guyader, Dominique, MD, Grangé, Jean-Didier, MD, Loustaud-Ratti, Véronique, MD, Serfaty, Lawrence, MD, Metivier, Sophie, MD, Leroy, Vincent, MD, Abergel, Armand, MD, Pol, Stanislas, MD

“…Summary Background Patients with cirrhosis resulting from chronic hepatitis C virus (HCV) infection are at risk of life-threatening complications, but…”
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Ledipasvir-sofosbuvir in patients with hepatitis C virus genotype 5 infection: an open-label, multicentre, single-arm, phase 2 study by Abergel, Armand, Prof, Asselah, Tarik, Prof, Metivier, Sophie, MD, Kersey, Kathryn, MSc, Jiang, Deyuan, PhD, Mo, Hongmei, MD, Pang, Phillip S, MD, Samuel, Didier, MD, Loustaud-Ratti, Véronique, Prof

“…Summary Background Data about the response of hepatitis C virus (HCV) genotype 5 to approved and experimental treatment regimens are scarce. We assessed the…”
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Arabidopsis Seedling Lethal 1 Interacting With Plastid-Encoded RNA Polymerase Complex Proteins Is Essential for Chloroplast Development by Jiang, Deyuan, Tang, Renjie, Shi, Yafei, Ke, Xiangsheng, Wang, Yetao, Che, Yufen, Luan, Sheng, Hou, Xin

“…Mitochondrial transcription termination factors (mTERFs) are highly conserved proteins in metazoans. Plants have many more mTERF proteins than animals. The…”
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Integrated safety analysis of filgotinib treatment for rheumatoid arthritis in patients from Japan over a median of 1.5 years by Ishiguro, Naoki, Tanaka, Yoshiya, Matsubara, Tsukasa, Atsumi, Tatsuya, Amano, Koichi, Sugiyama, Eiji, Yamaoka, Kunihiro, Winthrop, Kevin, Kivitz, Alan, Burmester, Gerd R, Gottenberg, Jacques-Eric, Genovese, Mark C, Matzkies, Franziska, Guo, Ying, Jiang, Deyuan, Bartok, Beatrix, Pechonkina, Alena, Kondo, Akira, Besuyen, Robin, Takeuchi, Tsutomu

“…Characterize safety of the Janus kinase-1 preferential inhibitor filgotinib (FIL) in Japanese patients with moderately to severely active rheumatoid arthritis…”
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Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years by Winthrop, Kevin L, Tanaka, Yoshiya, Takeuchi, Tsutomu, Kivitz, Alan, Matzkies, Franziska, Genovese, Mark C, Jiang, Deyuan, Chen, Kun, Bartok, Beatrix, Jahreis, Angelika, Besuyen, Robin, Burmester, Gerd R, Gottenberg, Jacques-Eric

“…To characterise safety of the Janus kinase-1 preferential inhibitor filgotinib in patients with moderately to severely active rheumatoid arthritis. Data were…”
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Ledipasvir plus sofosbuvir for 12 weeks in patients with hepatitis C genotype 4 infection by Abergel, Armand, Metivier, Sophie, Samuel, Didier, Jiang, Deyuan, Kersey, Kathryn, Pang, Phillip S., Svarovskaia, Evguenia, Knox, Steven J., Loustaud‐Ratti, Veronique, Asselah, Tarik

“…Genotype 4 hepatitis C virus (HCV) was considered difficult to treat in the era of pegylated interferon‐alpha (Peg‐IFN‐α) and ribavirin regimens. We evaluated…”
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YELLOW, SERRATED LEAF is essential for cotyledon vein patterning in Arabidopsis by Wang, Yetao, Zheng, Yutong, Shi, Yafei, Jiang, Deyuan, Kuang, Qi, Ke, Xiangsheng, Li, Ming, Wang, Yukun, Yue, Xiaohong, Lu, Qin, Hou, Xin

“…Venation develops complex patterns within the leaves of angiosperms, and the mechanism of leaf vein patterning remains poorly understood. Here, we report a…”
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Sofosbuvir plus ribavirin for treating Egyptian patients with hepatitis C genotype 4 by Doss, Wahid, Shiha, Gamal, Hassany, Mohamed, Soliman, Reham, Fouad, Rabab, Khairy, Marwa, Samir, Waleed, Hammad, Radi, Kersey, Kathryn, Jiang, Deyuan, Doehle, Brian, Knox, Steven J, Massetto, Benedetta, McHutchison, John G, Esmat, Gamal

“…Background & Aims Egypt has the highest prevalence of chronic hepatitis C virus (HCV) infection in the world, and more than 90% of patients are infected with…”
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Phase 1b study of GS-3583, a novel FLT3 agonist Fc fusion protein, in patients with advanced solid tumors by Tolcher, Anthony W., Brody, Joshua, Rajakumaraswamy, Nishanthan, Lakhani, Nehal J., Kuhne, Michelle R., Trowe, Torsten, Jiang, Deyuan, Dauki, Anees, Kummar, Shivaani

“…2566 Background: We have previously shown that systemic administration of GS-3583, a Fms-like tyrosine kinase 3 (FLT3) agonist Fc fusion protein leads to…”
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Sofosbuvir plus ribavirin for the treatment of chronic genotype 4 hepatitis C virus infection in patients of Egyptian ancestry by Ruane, Peter J, Ain, Dani, Stryker, Richard, Meshrekey, Raymond, Soliman, Mina, Wolfe, Peter R, Riad, Joseph, Mikhail, Sameh, Kersey, Kathryn, Jiang, Deyuan, Massetto, Benedetta, Doehle, Brian, Kirby, Brian J, Knox, Steven J, McHutchison, John G, Symonds, William T

“…Background & Aims We conducted an open-label phase 2 study to assess the efficacy and safety of the oral nucleotide polymerase inhibitor sofosbuvir in…”
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Efficacy of Ledipasvir and Sofosbuvir Treatment of HCV Infection in Patients Coinfected With HBV by Liu, Chun-Jen, Chuang, Wan-Long, Sheen, I-Shyan, Wang, Horng-Yuan, Chen, Chi-Yi, Tseng, Kuo-Chih, Chang, Ting-Tsung, Massetto, Benedetta, Yang, Jenny C., Yun, Chohee, Knox, Steven J., Osinusi, Anu, Camus, Gregory, Jiang, Deyuan, Brainard, Diana M., McHutchison, John G., Hu, Tsung-Hui, Hsu, You-Chun, Lo, Gin-Ho, Chu, Chi-Jen, Chen, Jyh-Jou, Peng, Cheng-Yuan, Chien, Ron-Nan, Chen, Pei-Jer

“…There have been reports of reactivation of hepatitis B virus (HBV) infection during treatment of hepatitis C virus (HCV) infection with direct-acting antiviral…”
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Sofosbuvir (GS-7977) plus peginterferon/ribavirin in treatment-naïve patients with HCV genotype 1: A randomized, 28-day, dose-ranging trial by Rodriguez-Torres, Maribel, Lawitz, Eric, Kowdley, Kris V, Nelson, David R, DeJesus, Edwin, McHutchison, John G, Cornpropst, Melanie T, Mader, Michael, Albanis, Efsevia, Jiang, Deyuan, Hebner, Christy M, Symonds, William T, Berrey, Michelle M, Lalezari, Jay

“…Background & Aims Sofosbuvir (formerly GS-7977) is a pyrimidine nucleotide analog inhibitor of the hepatitis C virus (HCV) NS5B polymerase. We assessed the…”
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Comparison of the efficacy of sofosbuvir plus ribavirin in Chinese patients with genotype 3a or 3b HCV infection by Huang, Rui, Rao, Huiying, Xie, Qing, Gao, Zhiliang, Li, Wu, Jiang, Deyuan, Mo, Hongmei, Massetto, Benedetta, Stamm, Luisa M., Brainard, Diana M., Wei, Lai

“…Background and Aim Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of…”
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Ledipasvir/Sofosbuvir for Patients Coinfected With Chronic Hepatitis C and Hepatitis B in Taiwan: Follow-up at 108 Weeks Posttreatment by Liu, Chun Jen, Sheen, I Shyan, Chen, Chi Yi, Chuang, Wan Long, Wang, Horng Yuan, Tseng, Kuo Chih, Chang, Ting Tsung, Yang, Jenny, Massetto, Benedetta, Suri, Vithika, Camus, Gregory, Jiang, Deyuan, Zhang, Fangqiu, Gaggar, Anuj, Hu, Tsung Hui, Hsu, Yu Chun, Lo, Gin Ho, Chu, Chi Jen, Chen, Jyh Jou, Peng, Cheng Yuan, Chien, Rong Nan, Chen, Pei Jer

“…For patients coinfected with hepatitis C virus (HCV) and hepatitis B virus (HBV), HCV treatment with direct-acting antivirals can lead to HBV reactivation. We…”
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Ledipasvir‐sofosbuvir for treating Japanese patients with chronic hepatitis C virus genotype 2 infection by Asahina, Yasuhiro, Itoh, Yoshito, Ueno, Yoshiyuki, Matsuzaki, Yasushi, Takikawa, Yasuhiro, Yatsuhashi, Hiroshi, Genda, Takuya, Ikeda, Fusao, Matsuda, Takuma, Dvory‐Sobol, Hadas, Jiang, Deyuan, Massetto, Benedetta, Osinusi, Anu O., Brainard, Diana M., McHutchison, John G., Kawada, Norifumi, Enomoto, Nobuyuki

“…Background & Aims Japanese patients with chronic hepatitis C virus (HCV) genotype 2 infection have high rates of sustained virological response (SVR) following…”
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Sofosbuvir–velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals by Izumi, Namiki, Takehara, Tetsuo, Chayama, Kazuaki, Yatsuhashi, Hiroshi, Takaguchi, Koichi, Ide, Tatsuya, Kurosaki, Masayuki, Ueno, Yoshiyuki, Toyoda, Hidenori, Kakizaki, Satoru, Tanaka, Yasuhito, Kawakami, Yoshiiku, Enomoto, Hirayuki, Ikeda, Fusao, Jiang, Deyuan, De-Oertel, Shampa, McNabb, Brian L., Camus, Gregory, Stamm, Luisa M., Brainard, Diana M., McHutchison, John G., Mochida, Satoshi, Mizokami, Masashi

“…Background/purpose In Japan, there is a growing population of patients with chronic hepatitis C virus (HCV) infection who failed a direct-acting antiviral…”
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Transcription factor CsESE3 positively modulates both jasmonic acid and wax biosynthesis in citrus by Wan, Haoliang, Qiu, Haiji, Li, Zhuoran, Zhang, Xiaoliang, Zhang, Jingyu, Jiang, Deyuan, Fernie, Alisdair R., Lyu, Yi, Cheng, Yunjiang, Wen, Weiwei

“…PLIP lipases can initiate jasmonic acid (JA) biosynthesis. However, little is known about the transcriptional regulation of this process. In this study, an ERF…”
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1876-P: Impact of Diabetes on Liver Disease Progression in Patients with Advanced Fibrosis Due to Nonalcoholic Steatohepatitis (NASH) by SANYAL, ARUN J., ABDELMALEK, MANAL F., CALDWELL, STEPHEN, SHIFFMAN, MITCHELL L., GHALIB, REEM, LAWITZ, ERIC, JIANG, DEYUAN, AGUILAR SCHALL, RAUL E., MCCOLGAN, BRYAN J., MYERS, ROB, DJEDJOS, STEPHEN, MUIR, ANDREW, RATZIU, VLAD, AFDHAL, NEZAM, GOODMAN, ZACHARY, BOSCH, JAIME, HARRISON, STEPHEN A.

“…Background: Diabetes is a risk factor for advanced fibrosis due to NASH, but the effect of diabetes on disease progression is not well-characterized. Here, we…”
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