Search Results - "JHEP reports"

Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper by Boettler, Tobias, Newsome, Philip N., Mondelli, Mario U., Maticic, Mojca, Cordero, Elisa, Cornberg, Markus, Berg, Thomas

“…The coronavirus disease 2019 (COVID-19) pandemic poses an enormous challenge to healthcare systems in affected communities. Older patients and those with…”
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From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options by Gastaldelli, Amalia, Cusi, Kenneth

“…The worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to have reached 25% or more in adults. NAFLD is prevalent in obese…”
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Non-alcoholic fatty liver disease: A patient guideline by Francque, Sven M., Marchesini, Giulio, Kautz, Achim, Walmsley, Martine, Dorner, Rebecca, Lazarus, Jeffrey V., Zelber-Sagi, Shira, Hallsworth, Kate, Busetto, Luca, Frühbeck, Gema, Dicker, Dror, Woodward, Euan, Korenjak, Marko, Willemse, José, Koek, Gerardus H., Vinker, Shlomo, Ungan, Mehmet, Mendive, Juan M., Lionis, Christos

“…This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty liver disease (NAFLD). NAFLD is the most frequent chronic…”
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Lipid alterations in chronic liver disease and liver cancer by Paul, Bichitra, Lewinska, Monika, Andersen, Jesper B.

“…Lipids are a complex and diverse group of molecules with crucial roles in many physiological processes, as well as in the onset, progression, and maintenance…”
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Limitations of non-invasive tests for assessment of liver fibrosis by Patel, Keyur, Sebastiani, Giada

“…The diagnostic assessment of liver injury is an important step in the management of patients with chronic liver disease (CLD). Although liver biopsy is the…”
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New targets for NAFLD by Parlati, Lucia, Régnier, Marion, Guillou, Hervé, Postic, Catherine

“…Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease worldwide. It is characterised by steatosis, liver inflammation,…”
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NAFLD and liver transplantation: Disease burden, current management and future challenges by Burra, Patrizia, Becchetti, Chiara, Germani, Giacomo

“…Non-alcoholic fatty liver disease (NAFLD), specifically its progressive form non-alcoholic steatohepatitis (NASH), represents the fastest growing indication…”
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Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism by Lefere, Sander, Tacke, Frank

“…Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide, and a major cause of liver cirrhosis and hepatocellular carcinoma…”
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Lifestyle modification in NAFLD/NASH: Facts and figures by Hallsworth, Kate, Adams, Leon A.

“…The development of non-alcoholic fatty liver disease is closely linked to lifestyle factors, namely excessive caloric intake coupled with reduced physical…”
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Epidemiology of non-alcoholic fatty liver disease and hepatocellular carcinoma by Younossi, Zobair M., Henry, Linda

“…The prevalence of hepatocellular carcinoma (HCC) is increasing worldwide, whereas that of most other cancers is decreasing. Non-alcoholic fatty liver disease…”
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Impact of COVID-19 on the care of patients with liver disease: EASL-ESCMID position paper after 6 months of the pandemic by Boettler, Tobias, Marjot, Thomas, Newsome, Philip N., Mondelli, Mario U., Maticic, Mojca, Cordero, Elisa, Jalan, Rajiv, Moreau, Richard, Cornberg, Markus, Berg, Thomas

“…During the early stages of the coronavirus disease 2019 (COVID-19) pandemic, EASL and ESCMID published a position paper to provide guidance for physicians…”
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Treatment of NAFLD with intermittent calorie restriction or low-carb high-fat diet – a randomised controlled trial by Holmer, Magnus, Lindqvist, Catarina, Petersson, Sven, Moshtaghi-Svensson, John, Tillander, Veronika, Brismar, Torkel B., Hagström, Hannes, Stål, Per

“…The first-line treatment for non-alcoholic fatty liver disease (NAFLD) is weight reduction. Several diets have been proposed, with various effects specifically…”
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Acute-on-chronic liver failure: Definitions, pathophysiology and principles of treatment by Zaccherini, Giacomo, Weiss, Emmanuel, Moreau, Richard

“…The term acute-on-chronic liver failure (ACLF) defines an abrupt and life-threatening worsening of clinical conditions in patients with cirrhosis or chronic…”
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Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy by Iwakiri, Yasuko, Trebicka, Jonel

“…Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the…”
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Artificial intelligence in liver diseases: Improving diagnostics, prognostics and response prediction by Nam, David, Chapiro, Julius, Paradis, Valerie, Seraphin, Tobias Paul, Kather, Jakob Nikolas

“…Clinical routine in hepatology involves the diagnosis and treatment of a wide spectrum of metabolic, infectious, autoimmune and neoplastic diseases. Clinicians…”
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ALBI grade: Evidence for an improved model for liver functional estimation in patients with hepatocellular carcinoma by Demirtas, Coskun O., D’Alessio, Antonio, Rimassa, Lorenza, Sharma, Rohini, Pinato, David J.

“…Hepatocellular carcinoma (HCC) usually arises in the context of a chronically damaged liver. Liver functional estimation is of paramount importance in clinical…”
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Liver toxicity as a limiting factor to the increasing use of immune checkpoint inhibitors by De Martin, Eleonora, Michot, Jean-Marie, Rosmorduc, Olivier, Guettier, Catherine, Samuel, Didier

“…Immune checkpoint inhibitors (ICIs) improve clinical outcomes in patients suffering from different types of cancer. Liver toxicity is one of the immune-related…”
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Organoids to model liver disease by Nuciforo, Sandro, Heim, Markus H.

“…The organoid model represents a major breakthrough in cell biology that has revolutionised biomedical research. Organoids are 3D physiological in vitro…”
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Novel vectors and approaches for gene therapy in liver diseases by Maestro, Sheila, Weber, Nicholas D., Zabaleta, Nerea, Aldabe, Rafael, Gonzalez-Aseguinolaza, Gloria

“…Gene therapy is becoming an increasingly valuable tool to treat many genetic diseases with no or limited treatment options. This is the case for hundreds of…”
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Non-alcoholic fatty liver disease in lean individuals by Albhaisi, Somaya, Chowdhury, Abhijit, Sanyal, Arun J.

“…Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease, encompassing a spectrum from non-alcoholic fatty liver to non-alcoholic…”
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