Search Results - "JEPEAL, L"

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes by Epstein, J, Cai, J, Glaser, T, Jepeal, L, Maas, R

“…Pax genes encode a family of developmentally regulated transcription factors that have been implicated in a number of human and murine congenital disorders, as…”
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Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing by Epstein, J A, Glaser, T, Cai, J, Jepeal, L, Walton, D S, Maas, R L

“…Vertebrate Pax proteins share a conserved 128-amino-acid DNA-binding motif, the paired domain. The PAX6 gene, which is mutated in the murine Small eye and…”
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Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins by PHILIPPE, J, DRUCKER, D. J, KNEPEL, W, JEPEAL, L, MISULOVIN, Z, HABENER, J. F

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A pancreatic islet cell-specific enhancer-like element in the glucagon gene contains two domains binding distinct cellular proteins by KNEPEL, W, JEPEAL, L, HABENER, J. F

“…Interactions of nuclear proteins with cis-control elements are involved in the programmed developmental expression of the islet polypeptide hormone genes…”
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Glucagon gene 5'-flanking sequences promote islet cell-specific gene transcription by Drucker, D J, Philippe, J, Jepeal, L, Habener, J F

“…Glucagon, a peptide hormone which regulates hepatic carbohydrate metabolism, is processed from a larger precursor, proglucagon. The gene encoding proglucagon…”
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Cell-specific Expression of the Glucose-dependent Insulinotropic Polypeptide Gene in a Mouse Neuroendocrine Tumor Cell Line by Boylan, Michael O., Jepeal, Lisa I., Jarboe, Linda A., Wolfe, M. Michael

“…Glucose-dependent insulinotropic polypeptide (GIP) is a 42-amino acid gastrointestinal regulatory peptide that, in the presence of glucose, stimulates insulin…”
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Structure of the rat glucose-dependent insulinotropic polypeptide receptor gene by Boylan, Michael O, Jepeal, Lisa I, Wolfe, M.Michael

“…1 The Glucose-dependent insulinotropic polypeptide receptor (GIPR) is a member of the secretin-vasoactive intestinal polypeptide family of G-protein coupled…”
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PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects by Glaser, Tom, Jepeal, Lisa, Edwards, Janice G, Young, S. Robert, Favor, Jack, Maas, Richard L

“…The human eye malformation aniridia results from haploinsufficiency of PAX6, a paired box DNA-binding protein. To study this dosage effect, we characterized…”
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Pax3 Inhibits Myogenic Differentiation of Cultured Myoblast Cells by Epstein, Jonathan A., Lam, Paula, Jepeal, Lisa, Maas, Richard L., Shapiro, David N.

“…Pax3 is an evolutionarily conserved transcription factor expressed in the lateral dermomyotome, a region that gives rise to limb muscle progenitors. Mutations…”
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Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene functions through a PDX-1 motif in a mouse neuroendocrine tumor cell line by JEPEAL, L, BOYLAN, M, MICHAELWOLFE, M

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A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs by Maas, R L, Jepeal, L I, Elfering, S L, Holcombe, R F, Morton, C C, Eddy, R L, Byers, M G, Shows, T B, Leder, P

“…The murine limb deformity (ld) locus resides on mouse chromosome 2 and gives rise to a recessively inherited, characteristic limb deformity/renal aplasia…”
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cis-acting DNA sequence controls glucagon gene expression in pancreatic islet cells by Drucker, D J, Philippe, J, Jepeal, L, Habener, J F

“…Our studies show that cis-acting DNA sequences present in the 5'-flanking region are important for the promotion of glucagon gene transcription in islet cell…”
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Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation by Maas, Richard, Elfering, Sandra, Glaser, Tom, Jepeal, Lisa

“…Mice which are homozygous for the limb deformity (ld) mutation also manifest an incompletely penetrant unilateral or bilateral renal agenesis phenotype…”
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Cell-Specific Expression of Glucose-Dependent-Insulinotropic Polypeptide Is Regulated by the Transcription Factor PDX-1 by Jepeal, Lisa I, Fujitani, Yoshio, Boylan, Michael O, Wilson, Cherrell N, Wright, Christopher V, Wolfe, M. Michael

“…Glucose-dependent insulinotropic polypeptide (GIP) is a potent stimulator of insulin secretion and comprises an important component of the enteroinsular axis…”
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Deficient outgrowth of the ureteric bud underies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation by MAAS, R, ELFERING, S, GLASER, T, JEPEAL, L

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Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene functions through a GATA and an ISL-1 motif in a mouse neuroendocrine tumor cell line by Jepeal, Lisa I., Boylan, Michael O., Wolfe, M.Michael

“…Background/aims: Glucose-dependent insulinotropic polypeptide (GIP) is a 42-amino acid gastrointestinal regulatory peptide that, in the presence of glucose,…”
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Gastrin stimulates receptor-mediated proliferation of human esophageal adenocarcinoma cells by Moore, T.Carlton, Jepeal, Lisa I., Boylan, Michael O., Singh, Satish K., Boyd, Nick, Beer, David G., Chang, Albert J., Wolfe, M.Michael

“…The prevalence of esophageal adenocarcinoma in the setting of Barrett's metaplasia continues to increase in Western nations at a rate greater than any other…”
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Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins by Philippe, J, Drucker, D J, Knepel, W, Jepeal, L, Misulovin, Z, Habener, J F

“…The authors show here that 300 base pairs of the 5'-flanking region of the rat glucagon gene, linked to a chloramphenicol acetyltransferase reporter plasmid…”
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A human gene homologous to the formin gene residing at the murine lim deformity locus chromosomal location and RFLPs by MAAS, R. L, JEPEAL, L. I, ELFERING, S. L, HOLCOMBE, R. F, MORTON, C. C, EDDY, R. L, BYERS, M. G, SHOWS, T. B, LEDER, P

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