Search Results - "JENSEN, NICOLE J."

On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA by Wewer Albrechtsen, Nicolai J., Kjeldsen, Sasha A. S., Jensen, Nicole J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, Kirstine N., Dirksen, Carsten, Jensen, Christian Z., Martinussen, Christoffer, Madsbad, Sten, Holst, Jens J.

“…Glucagon is a key regulator of metabolism and is used in the diagnostic of neuroendocrine tumors. Accurate measurement of glucagon requires both extreme…”
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Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy by Kjeldsen, Sasha A.S., Gluud, Lise L., Werge, Mikkel P., Pedersen, Julie S., Bendtsen, Flemming, Alexiadou, Kleopatra, Tan, Tricia, Torekov, Signe S., Iepsen, Eva W., Jensen, Nicole J., Richter, Michael M., Goetze, Jens P., Rungby, Jørgen, Hartmann, Bolette, Holst, Jens J., Holst, Birgitte, Holt, Joachim, Gustafsson, Finn, Madsbad, Sten, Svane, Maria S., Bojsen-Møller, Kirstine N., Wewer Albrechtsen, Nicolai J.

“…Inhibitors of neprilysin improve glycemia in patients with heart failure and type 2 diabetes (T2D). The effect of weight loss by diet, surgery, or…”
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1543-P: The Effect of Insulin Resistance on Brain Glucose Uptake—A Systematic Review and Meta-analysis by JENSEN, NICOLE J., PORSE, ANE J., SPEYER, HELENE, KROGH, JESPER, GEJL, MICHAEL, GJEDDE, ALBERT H., RUNGBY, JØRGEN

“…Objective: We investigated the association between peripheral insulin resistance (IR) and brain glucose uptake (BGU) and further determined if testing…”
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Relation of Insulin Resistance to Brain Glucose Metabolism in Fasting and Hyperinsulinemic States: A Systematic Review and Meta-Analysis by Jensen, Nicole J, Porse, Ane J, Wodschow, Helena Z, Speyer, Helene, Krogh, Jesper, Marner, Lisbeth, Gejl, Michael, Gjedde, Albert, Rungby, Jørgen

“…Abnormal brain glucose metabolism may cause cognitive disease in type 2 diabetes, yet the relation between insulin resistance and brain glucose metabolism has…”
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1385-P: Impact of Preanalytical and Analytical Factors on Glucagon and GLP-1 Levels in Humans by RASMUSSEN, CHRISTINE, KJELDSEN, SASHA, JENSEN, NICOLE J., HEINZ, NIKLAS, HARTMANN, BOLETTE, HOLST, JENS J., ALBRECHTSEN, NICOLAI J. WEWER

“…Glucagon and glucagon-like peptide-1 (GLP-1) have important roles in the development and treatment of diabetes. Their plasma concentrations are currently being…”
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Glucagon does not directly stimulate pituitary secretion of ACTH, GH or copeptin by Stangerup, Ida, Kjeldsen, Sasha A.S., Richter, Michael M., Jensen, Nicole J., Rungby, Jørgen, Haugaard, Steen Bendix, Georg, Birgitte, Hannibal, Jens, Møllgård, Kjeld, Wewer Albrechtsen, Nicolai J., Bjørnbak Holst, Camilla

“…Glucagon is best known for its contribution to glucose regulation through activation of the glucagon receptor (GCGR), primarily located in the liver. However,…”
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Glucagon resistance in individuals with obesity and hepatic steatosis can be measured using the GLUSENTIC test and index by Kjeldsen, Sasha A S, Richter, Michael M, Jensen, Nicole J, Nilsson, Malin S D, Heinz, Niklas, Nybing, Janus D, Linden, Frederik H, Høgh-Schmidt, Erik, Boesen, Mikael P, Andersen, Thomas L, Johannesen, Helle H, Trammell, Samuel A J, Grevengoed, Trisha J, Madsbad, Sten, Vilstrup, Hendrik, Vinholt Schiødt, Frank, Møller, Andreas, Rashu, Elias B, Nørgaard, Kirsten, Schmidt, Signe, Gluud, Lise L, Haugaard, Steen B, Holst, Jens J, Rungby, Jørgen, Wewer Albrechtsen, Nicolai J

“…Increased plasma levels of glucagon (hyperglucagonaemia) promote diabetes development but is also observed in patients with metabolic dysfunction-associated…”
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Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms by Richter, Michael M., Kemp, Ida M., Heebøll, Sara, Winther-Sørensen, Marie, Kjeldsen, Sasha A.S., Jensen, Nicole J., Nybing, Janus D., Linden, Frederik H., Høgh-Schmidt, Erik, Boesen, Mikael P., Madsbad, Sten, Schiødt, Frank Vinholt, Nørgaard, Kirsten, Schmidt, Signe, Gluud, Lise Lotte, Haugaard, Steen B., Holst, Jens J., Nielsen, Søren, Rungby, Jørgen, Wewer Albrechtsen, Nicolai J.

“…Glucagon receptor agonism is currently explored for the treatment of obesity and metabolic dysfunction-associated steatotic liver disease (MASLD). The…”
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1343-P: The Acute Effects of Glucagon on Glucose Dynamics Are Not Impaired in Individuals with Nonalcoholic Fatty Liver Disease by KJELDSEN, SASHA, JENSEN, NICOLE J., NILSSON, MALIN, HEINZ, NIKLAS, NYBING, JANUS D., LINDEN, FREDERIK H., HØGH-SCHMIDT, ERIK, BOESEN, MIKAEL P., MADSBAD, STEN, VILSTRUP, HENDRIK, SCHIØDT, FRANK V., MØLLER, ANDREAS, RASHU, ELIAS B., GLUUD, LISE, HAUGAARD, STEEN B., HOLST, JENS J., RUNGBY, JOERGEN, WEWER ALBRECHTSEN, NICOLAI J.

“…Glucagon is essential for glucose control and increased levels of glucagon (hyperglucagonemia) observed in patients with type 2 diabetes contribute to their…”
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216-LB: Development and Evaluation of a Glucagon Sensitivity Test in Humans by KJELDSEN, SASHA, JENSEN, NICOLE J., NILSSON, MALIN, NYBING, JANUS D., LINDEN, FREDERIK H., HØGH-SCHMIDT, ERIK, BOESEN, MIKAEL P., MADSBAD, STEN, VILSTRUP, HENDRIK, RASHU, ELIAS B., GLUUD, LISE, HAUGAARD, STEEN B., HOLST, JENS J., RUNGBY, JOERGEN, ALBRECHTSEN, NICOLAI J. WEWER

“…Glucagon regulates hepatic glucose production and hyperglucagonemia contributes to diabetes. Equally important, glucagon may regulate amino acid (AA) levels…”
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36-LB: The Effect of Dietary Carbohydrate Restriction on Health-Related Quality of Life and Cognition: A Randomized Trial by JENSEN, NICOLE J., WODSCHOW, HELENA Z., SKYTTE, MADS J., SAMKANI, AMIRSALAR, ASTRUP, ARNE, FRYSTYK, JAN, HARTMANN, BOLETTE, HOLST, JENS J., LARSEN, THOMAS M., MADSBAD, STEN, MAGKOS, FAIDON, MISKOWIAK, KAMILLA, RUNGBY, JOERGEN, HAUGAARD, STEEN B., KRARUP, THURE, THOMSEN, MADS N.

“…Objective: We aimed to evaluate the effect of weight loss induced by a carbohydrate-reduced high-protein (CRHP) diet on physical and mental health and…”
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Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials by Rasmussen, Christine, Richter, Michael M, Jensen, Nicole J, Heinz, Niklas, Hartmann, Bolette, Holst, Jens J, Kjeldsen, Sasha A S, Wewer Albrechtsen, Nicolai J

“…Plasma concentrations of glucagon, GLP-1 and GIP are reported in numerous clinical trials as outcome measures but preanalytical guidelines are lacking. We…”
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Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol by Kjeldsen, Sasha A.S., Richter, Michael M., Jensen, Nicole J., Nilsson, Malin S.D., Heinz, Niklas, Nybing, Janus D., Linden, Frederik H., Høgh-Schmidt, Erik, Boesen, Mikael P., Madsbad, Sten, Vilstrup, Hendrik, Schiødt, Frank Vinholt, Møller, Andreas, Nørgaard, Kirsten, Schmidt, Signe, Rashu, Elias B., Gluud, Lise L., Haugaard, Steen B., Holst, Jens J., Rungby, Jørgen, Wewer Albrechtsen, Nicolai J.

“…A physiological feedback system exists between hepatocytes and the alpha cells, termed the liver-alpha cell axis and refers to the relationship between amino…”
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368-P: Effects of Mild Hypoglycaemia on Cognitive Function in Type 2 Diabetes by NILSSON, MALIN, JENSEN, NICOLE J., GEJL, MICHAEL, BRANDSLUND, IVAN, STORGAARD, HEIDI, ZANDER, METTE, MISKOWIAK, KAMILLA, RUNGBY, JØRGEN

“…Background: Previous studies have demonstrated cognitive impairment during severe hypoglycaemia. This study provides quantitative results on cognitive function…”
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SAT032 Circulating Neprilysin Activity Is Increased In Type 2 Diabetes And Fatty Liver Disease, And Reduces Following Bariatric Surgery And Liraglutide Therapy by Sampson Kjeldsen, Sasha Alexandra, Lotte Gluud, Lise, Werge, Mikkel, Steen Pedersen, Julie, Bendtsen, Flemming, Alexiadou, Kleopatra, Tan, Tricia, Torekov, Signe S, Iepsen, Eva W, Jensen, Nicole J, Richter, Michael, Hartmann, Bolette, Holst, Jens J, Holst, Birgitte, Holt, Joachim, Madsbad, Sten, Svane, Maria S, Bojsen-Møller, Kirstine N, Wewer Albrechtsen, Nicolai J

“…Abstract Disclosure: S.A. Kjeldsen: None. L. Gluud: None. M. Werge: None. J. Pedersen: None. F. Bendtsen: None. K. Alexiadou: None. T. Tan: None. S.S. Torekov:…”
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