Search Results - "JEFFRIES, D"

Potential Roles of Redox Dysregulation in the Development of Schizophrenia by Perkins, Diana O., Jeffries, Clark D., Do, Kim Q.

“…Converging evidence implicates redox dysregulation as a pathological mechanism driving the emergence of psychosis. Increased oxidative damage and decreased…”
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Towards a psychosis risk blood diagnostic for persons experiencing high-risk symptoms: preliminary results from the NAPLS project by Perkins, Diana O, Jeffries, Clark D, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin S, Cannon, Tyrone D, Cornblatt, Barbara A, Mathalon, Daniel H, McGlashan, Thomas H, Seidman, Larry J, Tsuang, Ming T, Walker, Elaine F, Woods, Scott W, Heinssen, Robert

“…A barrier to preventative treatments for psychosis is the absence of accurate identification of persons at highest risk. A blood test that could substantially…”
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Polygenic Risk Score Contribution to Psychosis Prediction in a Target Population of Persons at Clinical High Risk by Perkins, Diana O, Olde Loohuis, Loes, Barbee, Jenna, Ford, John, Jeffries, Clark D, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin S, Cannon, Tyrone D, Cornblatt, Barbara A, Mathalon, Daniel H, McGlashan, Thomas H, Seidman, Larry J, Tsuang, Ming, Walker, Elaine F, Woods, Scott W

“…Objective:The 2-year risk of psychosis in persons who meet research criteria for a high-risk syndrome is about 15%−25%; improvements in risk prediction…”
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Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells by Midtvedt, Daniel, Olsén, Erik, Höök, Fredrik, Jeffries, Gavin D. M.

“…Microorganisms adapt their biophysical properties in response to changes in their local environment. However, quantifying these changes at the single-cell…”
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A lithium depletion boundary age of 21 Myr for the Beta Pictoris moving group by Binks, A. S., Jeffries, R. D.

“…Optical spectroscopy is used to confirm membership for eight low-mass candidates in the young Beta Pic moving group (BPMG) via their radial velocities,…”
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Membrane Tubulation in Lipid Vesicles Triggered by the Local Application of Calcium Ions by Ali Doosti, Baharan, Pezeshkian, Weria, Bruhn, Dennis S, Ipsen, John H, Khandelia, Himanshu, Jeffries, Gavin D. M, Lobovkina, Tatsiana

“…Experimental and theoretical studies on ion–lipid interactions predict that binding of calcium ions to cell membranes leads to macroscopic mechanical effects…”
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Nuclear and cytoplasmic localization of neural stem cell microRNAs by Jeffries, Clark D, Fried, Howard M, Perkins, Diana O

“…Although generally regarded as functional in the cytoplasm, a number of microRNAs (miRNAs) have been found in the nucleus, possibly with a role in gene…”
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Droplets for Ultrasmall-Volume Analysis by CHIU, Daniel T, LORENZ, Robert M, JEFFRIES, Gavin D. M

“…By using methods that permit the generation and manipulation of ultrasmall-volume droplets, researchers are pushing the boundaries of ultrasensitive chemical…”
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Are the spin axes of stars randomly aligned within a cluster? by Jackson, R. J., Jeffries, R. D.

“…We investigate to what extent the spin axes of stars in young open clusters are aligned. Assuming that the spin vectors lie uniformly within a conical section,…”
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Episodic acidification of 5 rivers in Canada's oil sands during snowmelt: A 25-year record by Alexander, A.C., Chambers, P.A., Jeffries, D.S.

“…Episodic acidification during snowmelt is a natural phenomenon that can be intensified by acidic deposition from heavy industry. In Canada's oil sands region,…”
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Endocytic uptake of monomeric amyloid-β peptides is clathrin- and dynamin-independent and results in selective accumulation of Aβ(1–42) compared to Aβ(1–40) by Wesén, Emelie, Jeffries, Gavin D. M., Matson Dzebo, Maria, Esbjörner, Elin K.

“…Intraneuronal accumulation of amyloid-β (Aβ) peptides represent an early pathological feature in Alzheimer’s disease. We have therefore utilized flow cytometry…”
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The Dynamics, Structure, and Fate of a Young Cluster during Gas Dispersal: Hectoschelle, Chandra, Spitzer, and Gaia Observations of Cep OB3b by Karnath, N., Prchlik, J. J., Gutermuth, R. A., Allen, T. S., Megeath, S. T., Pipher, J. L., Wolk, S., Jeffries, R. D.

“…We present a study of the kinematics and structure of the Cep OB3b cluster based on new spectra obtained with the Hectoschelle spectrograph on the MMT and data…”
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A maximum-likelihood method for fitting colour-magnitude diagrams by Naylor, Tim, Jeffries, R. D.

“…We present a maximum-likelihood method for fitting two-dimensional model distributions to stellar data in colour-magnitude space. This allows one to include…”
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Fluctuating NMDA Receptor Subunit Levels in Perirhinal Cortex Relate to Their Dynamic Roles in Object Memory Destabilization and Reconsolidation by Wideman, Cassidy E, Nguyen, James, Jeffries, Sean D, Winters, Boyer D

“…Reminder cues can destabilize consolidated memories, rendering them modifiable before they return to a stable state through the process of reconsolidation…”
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A kinematically unbiased search for nearby young stars in the Northern hemisphere selected using SuperWASP rotation periods by Binks, A. S., Jeffries, R. D., Maxted, P. F. L.

“…We present a kinematically-unbiased search to identify young, nearby low-mass members of kinematic moving groups (MGs). Objects with both rotation periods…”
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No wide spread of stellar ages in the Orion Nebula Cluster by Jeffries, R. D., Littlefair, S. P., Naylor, Tim, Mayne, N. J.

“…The wide luminosity dispersion seen for stars at a given effective temperature in the Hertzsprung-Russell diagrams of young clusters and star-forming regions…”
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The distance to the Orion Nebula cluster by Jeffries, R. D.

“…The distance to the Orion Nebula cluster (ONC) is estimated using the rotational properties of its low-mass pre-main-sequence (PMS) stars. Rotation periods,…”
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Why do some young cool stars show spot modulation while others do not? by Jackson, R. J., Jeffries, R. D.

“…We present far-red, intermediate-resolution spectroscopy of 572 photometrically selected, low-mass stars (0.2 < M/M⊙ < 0.7) in the young open cluster NGC 2516,…”
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Critical loads of acidity for 90,000 lakes in northern Saskatchewan: A novel approach for mapping regional sensitivity to acidic deposition by Cathcart, H., Aherne, J., Jeffries, D.S., Scott, K.A.

“…Atmospheric emissions of sulphur dioxide (SO2) from large point sources are the primary concern for acidic deposition in western Canada, particularly in the…”
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A greedy regression algorithm with coarse weights offers novel advantages by Jeffries, Clark D., Ford, John R., Tilson, Jeffrey L., Perkins, Diana O., Bost, Darius M., Filer, Dayne L., Wilhelmsen, Kirk C.

“…Regularized regression analysis is a mature analytic approach to identify weighted sums of variables predicting outcomes. We present a novel Coarse…”
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