Search Results - "JEFFREY SMITH, C"

Refine Results
  1. 1

    Respiratory rhythm generation in vivo by Richter, Diethelm W, Smith, Jeffrey C

    Published in Physiology (Bethesda, Md.) (01-01-2014)
    “…The cellular and circuit mechanisms generating the rhythm of breathing in mammals have been under intense investigation for decades. Here, we try to integrate…”
    Get full text
    Journal Article
  2. 2

    Regulation of myelin structure and conduction velocity by perinodal astrocytes by Dutta, Dipankar J., Woo, Dong Ho, Lee, Philip R., Pajevic, Sinisa, Bukalo, Olena, Huffman, William C., Wake, Hiroaki, Basser, Peter J., SheikhBahaei, Shahriar, Lazarevic, Vanja, Smith, Jeffrey C., Fields, R. Douglas

    “…The speed of impulse transmission is critical for optimal neural circuit function, but it is unclear how the appropriate conduction velocity is established in…”
    Get full text
    Journal Article
  3. 3

    Brainstem respiratory networks: building blocks and microcircuits by Smith, Jeffrey C, Abdala, Ana P.L, Borgmann, Anke, Rybak, Ilya A, Paton, Julian F.R

    Published in Trends in neurosciences (Regular ed.) (01-03-2013)
    “…Breathing movements in mammals are driven by rhythmic neural activity generated within spatially and functionally organized brainstem neural circuits…”
    Get full text
    Journal Article
  4. 4
  5. 5

    Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity by Sheikhbahaei, Shahriar, Turovsky, Egor A., Hosford, Patrick S., Hadjihambi, Anna, Theparambil, Shefeeq M., Liu, Beihui, Marina, Nephtali, Teschemacher, Anja G., Kasparov, Sergey, Smith, Jeffrey C., Gourine, Alexander V.

    Published in Nature communications (25-01-2018)
    “…Astrocytes are implicated in modulation of neuronal excitability and synaptic function, but it remains unknown if these glial cells can directly control…”
    Get full text
    Journal Article
  6. 6

    Efficient utilization of complex N-linked glycans is a selective advantage for Bacteroides fragilis in extraintestinal infections by Cao, Yanlu, Rocha, Edson R., Smith, C. Jeffrey

    “…Bacteroides fragilis is the most common anaerobe isolated from clinical infections, and in this report we demonstrate a characteristic of the species that is…”
    Get full text
    Journal Article
  7. 7

    Robustness of respiratory rhythm generation across dynamic regimes by Rubin, Jonathan E, Smith, Jeffrey C

    Published in PLoS computational biology (01-07-2019)
    “…A central issue in the study of the neural generation of respiratory rhythms is the role of the intrinsic pacemaking capabilities that some respiratory neurons…”
    Get full text
    Journal Article
  8. 8

    Organization of the core respiratory network: Insights from optogenetic and modeling studies by Ausborn, Jessica, Koizumi, Hidehiko, Barnett, William H, John, Tibin T, Zhang, Ruli, Molkov, Yaroslav I, Smith, Jeffrey C, Rybak, Ilya A

    Published in PLoS computational biology (01-04-2018)
    “…The circuit organization within the mammalian brainstem respiratory network, specifically within and between the pre-Bötzinger (pre-BötC) and Bötzinger (BötC)…”
    Get full text
    Journal Article
  9. 9

    Structural-functional properties of identified excitatory and inhibitory interneurons within pre-Botzinger complex respiratory microcircuits by Koizumi, Hidehiko, Koshiya, Naohiro, Chia, Justine X, Cao, Fang, Nugent, Joseph, Zhang, Ruli, Smith, Jeffrey C

    Published in The Journal of neuroscience (13-02-2013)
    “…We comparatively analyzed cellular and circuit properties of identified rhythmic excitatory and inhibitory interneurons within respiratory microcircuits of the…”
    Get full text
    Journal Article
  10. 10

    A closed-loop model of the respiratory system: focus on hypercapnia and active expiration by Molkov, Yaroslav I, Shevtsova, Natalia A, Park, Choongseok, Ben-Tal, Alona, Smith, Jeffrey C, Rubin, Jonathan E, Rybak, Ilya A

    Published in PloS one (10-10-2014)
    “…Breathing is a vital process providing the exchange of gases between the lungs and atmosphere. During quiet breathing, pumping air from the lungs is mostly…”
    Get full text
    Journal Article
  11. 11
  12. 12

    Structural and functional architecture of respiratory networks in the mammalian brainstem by Smith, Jeffrey C., Abdala, Ana P. L., Rybak, Ilya A., Paton, Julian F. R.

    “…Neural circuits controlling breathing in mammals are organized within serially arrayed and functionally interacting brainstem compartments extending from the…”
    Get full text
    Journal Article
  13. 13

    Raphe Neurons Stimulate Respiratory Circuit Activity by Multiple Mechanisms via Endogenously Released Serotonin and Substance P by Ptak, Krzysztof, Yamanishi, Tadashi, Aungst, Jason, Milescu, Lorin S, Zhang, Ruli, Richerson, George B, Smith, Jeffrey C

    Published in The Journal of neuroscience (25-03-2009)
    “…Brainstem serotonin (5-HT) neurons modulate activity of many neural circuits in the mammalian brain, but in many cases endogenous mechanisms have not been…”
    Get full text
    Journal Article
  14. 14

    Transgenic Mice Lacking Serotonin Neurons Have Severe Apnea and High Mortality during Development by Hodges, Matthew R, Wehner, Mackenzie, Aungst, Jason, Smith, Jeffrey C, Richerson, George B

    Published in The Journal of neuroscience (19-08-2009)
    “…Central serotonin (5-HT) neurons modulate many vital brain functions, including respiratory control. Whether breathing depends critically on 5-HT neurons, or…”
    Get full text
    Journal Article
  15. 15

    cis-Encoded Small RNAs, a Conserved Mechanism for Repression of Polysaccharide Utilization in Bacteroides by Cao, Yanlu, Förstner, Konrad U, Vogel, Jörg, Smith, C Jeffrey

    Published in Journal of bacteriology (15-09-2016)
    “…Bacteroides is a major component of the human gut microbiota which has a broad impact on the development and physiology of its host and a potential role in a…”
    Get full text
    Journal Article
  16. 16

    Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration by Marina, Nephtali, Abdala, Ana P, Trapp, Stefan, Li, Aihua, Nattie, Eugene E, Hewinson, James, Smith, Jeffrey C, Paton, Julian F R, Gourine, Alexander V

    Published in The Journal of neuroscience (15-09-2010)
    “…Phox2b-expressing neurons of the retrotrapezoid nucleus (RTN), located in the ventrolateral brainstem, are sensitive to changes in PCO(2)/pH, have excitatory…”
    Get full text
    Journal Article
  17. 17

    Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator by Phillips, Ryan S, Koizumi, Hidehiko, Molkov, Yaroslav I, Rubin, Jonathan E, Smith, Jeffrey C

    Published in eLife (07-07-2022)
    “…Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (I NaP ) and calcium-activated…”
    Get full text
    Journal Article
  18. 18
  19. 19

    Deficiency of the ferrous iron transporter FeoAB is linked with metronidazole resistance in Bacteroides fragilis by Veeranagouda, Yaligara, Husain, Fasahath, Boente, Renata, Moore, Jane, Smith, C Jeffrey, Rocha, Edson R, Patrick, Sheila, Wexler, Hannah M

    Published in Journal of antimicrobial chemotherapy (01-10-2014)
    “…Metronidazole is the most commonly used antimicrobial for Bacteroides fragilis infections and is recommended for prophylaxis of colorectal surgery…”
    Get full text
    Journal Article
  20. 20

    Characterization of the Primary Starch Utilization Operon in the Obligate Anaerobe Bacteroides fragilis: Regulation by Carbon Source and Oxygen by SPENCE, Cheryl, WELLS, W. Greg, SMITH, C. Jeffrey

    Published in Journal of Bacteriology (01-07-2006)
    “…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
    Get full text
    Journal Article