Search Results - "JEFFREY SMITH, C"
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1
Respiratory rhythm generation in vivo
Published in Physiology (Bethesda, Md.) (01-01-2014)“…The cellular and circuit mechanisms generating the rhythm of breathing in mammals have been under intense investigation for decades. Here, we try to integrate…”
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2
Regulation of myelin structure and conduction velocity by perinodal astrocytes
Published in Proceedings of the National Academy of Sciences - PNAS (13-11-2018)“…The speed of impulse transmission is critical for optimal neural circuit function, but it is unclear how the appropriate conduction velocity is established in…”
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3
Brainstem respiratory networks: building blocks and microcircuits
Published in Trends in neurosciences (Regular ed.) (01-03-2013)“…Breathing movements in mammals are driven by rhythmic neural activity generated within spatially and functionally organized brainstem neural circuits…”
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4
Kepler Presearch Data Conditioning I-Architecture and Algorithms for Error Correction in Kepler Light Curves
Published in Publications of the Astronomical Society of the Pacific (01-09-2012)“…ABSTRACT Kepler provides light curves of 156,000 stars with unprecedented precision. However, the raw data as they come from the spacecraft contain significant…”
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5
Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
Published in Nature communications (25-01-2018)“…Astrocytes are implicated in modulation of neuronal excitability and synaptic function, but it remains unknown if these glial cells can directly control…”
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6
Efficient utilization of complex N-linked glycans is a selective advantage for Bacteroides fragilis in extraintestinal infections
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2014)“…Bacteroides fragilis is the most common anaerobe isolated from clinical infections, and in this report we demonstrate a characteristic of the species that is…”
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7
Robustness of respiratory rhythm generation across dynamic regimes
Published in PLoS computational biology (01-07-2019)“…A central issue in the study of the neural generation of respiratory rhythms is the role of the intrinsic pacemaking capabilities that some respiratory neurons…”
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8
Organization of the core respiratory network: Insights from optogenetic and modeling studies
Published in PLoS computational biology (01-04-2018)“…The circuit organization within the mammalian brainstem respiratory network, specifically within and between the pre-Bötzinger (pre-BötC) and Bötzinger (BötC)…”
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9
Structural-functional properties of identified excitatory and inhibitory interneurons within pre-Botzinger complex respiratory microcircuits
Published in The Journal of neuroscience (13-02-2013)“…We comparatively analyzed cellular and circuit properties of identified rhythmic excitatory and inhibitory interneurons within respiratory microcircuits of the…”
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10
A closed-loop model of the respiratory system: focus on hypercapnia and active expiration
Published in PloS one (10-10-2014)“…Breathing is a vital process providing the exchange of gases between the lungs and atmosphere. During quiet breathing, pumping air from the lungs is mostly…”
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11
Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-2010)“…Development of cancer receptor-specific gold nanoparticles will allow efficient targeting/optimum retention of engineered gold nanoparticles within tumors and…”
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12
Structural and functional architecture of respiratory networks in the mammalian brainstem
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (12-09-2009)“…Neural circuits controlling breathing in mammals are organized within serially arrayed and functionally interacting brainstem compartments extending from the…”
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13
Raphe Neurons Stimulate Respiratory Circuit Activity by Multiple Mechanisms via Endogenously Released Serotonin and Substance P
Published in The Journal of neuroscience (25-03-2009)“…Brainstem serotonin (5-HT) neurons modulate activity of many neural circuits in the mammalian brain, but in many cases endogenous mechanisms have not been…”
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14
Transgenic Mice Lacking Serotonin Neurons Have Severe Apnea and High Mortality during Development
Published in The Journal of neuroscience (19-08-2009)“…Central serotonin (5-HT) neurons modulate many vital brain functions, including respiratory control. Whether breathing depends critically on 5-HT neurons, or…”
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15
cis-Encoded Small RNAs, a Conserved Mechanism for Repression of Polysaccharide Utilization in Bacteroides
Published in Journal of bacteriology (15-09-2016)“…Bacteroides is a major component of the human gut microbiota which has a broad impact on the development and physiology of its host and a potential role in a…”
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16
Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration
Published in The Journal of neuroscience (15-09-2010)“…Phox2b-expressing neurons of the retrotrapezoid nucleus (RTN), located in the ventrolateral brainstem, are sensitive to changes in PCO(2)/pH, have excitatory…”
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17
Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator
Published in eLife (07-07-2022)“…Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (I NaP ) and calcium-activated…”
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18
New functions of pirin proteins and a 2‐ketoglutarate: Ferredoxin oxidoreductase ortholog in Bacteroides fragilis metabolism and their impact on antimicrobial susceptibility to metronidazole and amixicile
Published in MicrobiologyOpen (Weinheim) (01-08-2024)“…The understanding of how central metabolism and fermentation pathways regulate antimicrobial susceptibility in the anaerobic pathogen Bacteroides fragilis is…”
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19
Deficiency of the ferrous iron transporter FeoAB is linked with metronidazole resistance in Bacteroides fragilis
Published in Journal of antimicrobial chemotherapy (01-10-2014)“…Metronidazole is the most commonly used antimicrobial for Bacteroides fragilis infections and is recommended for prophylaxis of colorectal surgery…”
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20
Characterization of the Primary Starch Utilization Operon in the Obligate Anaerobe Bacteroides fragilis: Regulation by Carbon Source and Oxygen
Published in Journal of Bacteriology (01-07-2006)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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