Search Results - "JEFFERY, R. E"

Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia by Poulsom, R, Pignatelli, M, Stetler-Stevenson, WG, Liotta, LA, Wright, PA, Jeffery, RE, Longcroft, JM, Rogers, L, Stamp, GW

“…We undertook an in situ hybridization study to localize the mRNAs for the 72 kda type IV collagenase (MMP-2) and its specific inhibitor (TIMP-2) in 12…”
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Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin by Poulsom, R, Hanby, A M, Pignatelli, M, Jeffery, R E, Longcroft, J M, Rogers, L, Stamp, G W

“…AIMS--To compare the localisation of mRNAs for the basement membrane degrading enzyme gelatinase A (72 kilodalton type IV collagenase) and its inhibitor TIMP-2…”
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Spasmolytic polypeptide is a major antral peptide: distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach by Hanby, A M, Poulsom, R, Singh, S, Elia, G, Jeffery, R E, Wright, N A

“…The regional differences in the distribution of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) within the stomach are not known. The aim of…”
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Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues by Wright, N A, Poulsom, R, Stamp, G W, Hall, P A, Jeffery, R E, Longcroft, J M, Rio, M C, Tomasetto, C, Chambon, P

“…The pS2 gene encodes for a small cysteine-rich protein, and was originally found by differential screening of a cDNA library from the human breast carcinoma…”
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A robust method for isotopic riboprobe in situ hybridisation to localise mRNAs in routine pathology specimens by Poulsom, R, Longcroft, J M, Jeffery, R E, Rogers, L A, Steel, J H

“…In situ Hybridisation (ISH) to detect mRNA is widely applicable to studies of human pathology and experimental models including transgenic mice, where it can…”
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Localization of intestinal trefoil-factor mRNA in rat stomach and intestine by hybridization In situ by CHINERY, R, POULSOM, R, ROGERS, L. A, JEFFERY, R. E, LONGCROFT, J. M, HANBY, A. M, WRIGHT, N. A

“…A cDNA encoding rat intestinal trefoil factor (rITF) was prepared by reverse transcription and PCR amplification. The sequence obtained was well conserved with…”
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Lysozyme gene expression in inflammatory bowel disease by Stamp, G W, Poulsom, R, Chung, L P, Keshav, S, Jeffery, R E, Longcroft, J A, Pignatelli, M, Wright, N A

“…Riboprobe in situ hybridization (rISH) demonstrates active lysozyme synthesis in ulcerative colitis and Crohn's disease. Maximal labeling was seen in Paneth…”
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Comparison of isotopic and non-isotopic labelling for in situ hybridisation of various mRNA targets with cRNA probes by Steel, J H, Jeffery, R E, Longcroft, J M, Rogers, L A, Poulsom, R

“…In situ hybridisation methods to localise messenger ribonucleic acid (mRNA) targets in tissue sections or cell preparations using riboprobes can be successful…”
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Reduction of metastasis in a murine mammary tumour model by heparin and polyinosinic-polycytidylic acid by Lee, A E, Rogers, L A, Longcroft, J M, Jeffery, R E

“…A murine mammary tumour model has been used to test the efficacy of a combination of heparin and the interferon inducer, poly I:C on spontaneous metastasis…”
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The epidermal growth factor receptor in human pancreatic cancer by Lemoine, N R, Hughes, C M, Barton, C M, Poulsom, R, Jeffery, R E, Klöppel, G, Hall, P A, Gullick, W J

“…The epidermal growth factor receptor (EGFR) and its ligands are thought to be important in the control of proliferation of many epithelial systems, including…”
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Comparison of metastatic cell lines derived from a murine mammary tumour, and reduction of metastasis by heparin by Lee, A E, Rogers, L A, Jeffery, R E, Longcroft, J M

“…A murine mammary carcinoma, which had a high potential for metastasis to the lungs, was established in culture, and from the parent line several clonally…”
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Metastasis of mammary tumours in mice: relationship with morphology of primary tumour, and reproductive background of host by Lee, A E, Pang, L S, Rogers, L A, Jeffery, R E

“…The lungs of BR6 breeding female mice which had developed spontaneous mammary tumours, were examined histologically for the presence of metastases. Metastatic…”
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