Search Results - "JAVORSKY, Martin"

Nocturnal intermittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database cohort study by TKACOVA, Ruzena, MCNICHOLAS, Walter T, JAVORSKY, Martin, FIETZE, Ingo, SLIWINSKI, Pawel, PARATI, Gianfranco, GROTE, Ludger, HEDNER, Jan

“…Systemic hypertension is associated with obstructive sleep apnoea syndrome (OSAS) but the pathophysiological mechanisms are incompletely understood. A…”
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Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men by STANCAKOVA, Alena, JAVORSKY, Martin, KUULASMAA, Teemu, HAFFNER, Steven M, KUUSISTO, Johanna, LAAKSO, Markku

“…Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men Alena Stančáková 1 , Martin Javorský 1 ,…”
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Treatment with sodium‐glucose cotransporter 2 inhibitors and risk of lower‐limb amputations by Tkáč, Ivan, Kozárová, Miriam, Yaluri, Alena Stančáková, Javorský, Martin

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Serotonin transporter 5-HTTLPR polymorphism and escitalopram treatment response in patients with major depressive disorder by Jarčušková, Dominika, Tkáč, Ivan, Hlaváčová, Nataša, Yaluri, Alena Stančáková, Kozárová, Miriam, Habalová, Viera, Klimčáková, Lucia, Židzik, Jozef, Javorský, Martin, Bednářová, Aneta

“…There is no doubt that genetic factors have the potential to predict the therapeutic outcomes of antidepressants in patients with major depressive disorder…”
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Decreased 25-Hydroxy Vitamin D Level Is Associated with All-Cause Mortality in Patients with Type 2 Diabetes at High Cardiovascular Risk by Stančáková Yaluri, Alena, Tkáč, Ivan, Tokarčíková, Katarína, Kozelová, Zuzana, Rašiová, Mária, Javorský, Martin, Kozárová, Miriam

“…Cardiovascular diseases are among the leading causes of morbidity and mortality, particularly in individuals with type 2 diabetes. There is a need for new…”
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Genetic variants associated with glycemic response to treatment with dipeptidylpeptidase 4 inhibitors by Űrgeová, Anna, Javorský, Martin, Klimčáková, Lucia, Židzik, Jozef, Šalagovič, Ján, Hubáček, Jaroslav A, Doubravová, Pavlina, Gotthardová, Ivana, Kvapil, Milan, Pelikánová, Terezie, Tkáč, Ivan, Yaluri, Alena Stančáková

“…We examined associations of eight SNPs in/near seven candidate genes with glycemic response to 6 month treatment with DPP4 inhibitors. 206 patients with type 2…”
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KCNQ1 gene polymorphism is associated with glycaemic response to treatment with DPP-4 inhibitors by Gotthardová, Ivana, Javorský, Martin, Klimčáková, Lucia, Kvapil, Milan, Schroner, Zbynek, Kozárová, Miriam, Malachovská, Zuzana, Ürgeová, Anna, Židzik, Jozef, Tkáč, Ivan

“…Highlights • A retrospective analysis of 137 consecutive Caucasian patients with type 2 diabetes (T2D) to determine the association between two KCNQ1 gene…”
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Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients by Zaharenko, Linda, Kalnina, Ineta, Geldnere, Kristine, Konrade, Ilze, Grinberga, Solveiga, Židzik, Jozef, Javorský, Martin, Lejnieks, Aivars, Nikitina-Zake, Liene, Fridmanis, Davids, Peculis, Raitis, Radovica-Spalvina, Ilze, Hartmane, Dace, Pugovics, Osvalds, Tkáč, Ivan, Klimčáková, Lucia, Pīrāgs, Valdis, Klovins, Janis

“…Objective(s) High variability in clinical response to metformin is often observed in type 2 diabetes (T2D) patients, and it highlights the need for…”
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Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová, Jana, Dravecká, Ingrid, Javorský, Martin, Petríková, Jana, Lazúrová, Ivica

“…Summary Objective To investigate prevalence of vitamin D deficiency and its relation to clinical, anthropometrical, and biochemical findings in polycystic…”
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The effect of alfacalcidiol and metformin on metabolic disturbances in women with polycystic ovary syndrome by Figurová, Jana, Dravecká, Ingrid, Petríková, Jana, Javorský, Martin, Lazúrová, Ivica

“…The aim of this randomized clinical trial (RCT) was to evaluate the effect of vitamin D supplementation in obese, insulin-resistant (IR) and vitamin…”
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A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes by Tkáč, Ivan, Javorský, Martin, Klimčáková, Lucia, Židzik, Jozef, Gaľa, Igor, Babjaková, Eva, Schroner, Zbynek, Štolfová, Mária, Hermanová, Hana, Habalová, Viera

“…Purpose The aim of the present study was to investigate possible associations of the single-nucleotide variants in six genes encoding the key molecules…”
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Association between TCF7L2 Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide by Javorský, Martin, Babjaková, Eva, Klimčáková, Lucia, Schroner, Zbynek, Židzik, Jozef, Štolfová, Mária, Šalagovič, Ján, Tkáč, Ivan

“…Previous studies showed associations between variants in TCF7L2 gene and the therapeutic response to sulfonylureas. All sulfonylureas stimulate insulin…”
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KCNJ11 gene E23K variant and therapeutic response to sulfonylureas by Javorsky, Martin, Klimcakova, Lucia, Schroner, Zbynek, Zidzik, Jozef, Babjakova, Eva, Fabianova, Maria, Kozarova, Miriam, Tkacova, Ruzena, Salagovic, Jan, Tkac, Ivan

“…Abstract Aims Potassium inwardly rectifier 6.2 subunit (Kir6.2) of the ATP-sensitive potassium (KATP ) channel encoded by KCNJ11 gene is a therapeutical target…”
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Occupational rhinitis in the Slovak Republic--a long-term retrospective study by Perečinský, Slavomir, Legáth, L'ubomír, Varga, Marek, Javorský, Martin, Bátora, Igor, Klimentová, Gabriela

“…Allergic and non-allergic rhinitis ranks among the common occupational health problems. However, data on the incidence of occupational rhinitis are lacking,…”
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Effects of apolipoprotein E genotype on serum lipids in obstructive sleep apnoea by TISKO, Radovan, SOPKOVA, Zuzana, HABALOVA, Viera, DORKOVA, Zuzana, SLABA, Eva, JAVORSKY, Martin, TKAC, Ivan, RIHA, Renata L, TKACOVA, Ruzena

“…There is increasing evidence that intermittent hypoxia resulting from obstructive sleep apnoea (OSA) is independently associated with dyslipidaemia. Currently,…”
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Beneficial effect of simvastatin treatment on LDL oxidation and antioxidant protection is more pronounced in combined hyperlipidemia than in hypercholesterolemia by Molčányiová, Angela, Stančáková, Alena, Javorský, Martin, Tkáč, Ivan

“…Beneficial effects of statin treatment on cardiovascular morbidity and mortality has been not entirely explained by the reduction in LDL-cholesterol level. We…”
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Variation in KCNQ1 is associated with therapeutic response to sulphonylureas by Schroner, Zbynek, Dobrikova, Martina, Klimcakova, Lucia, Javorsky, Martin, Zidzik, Jozef, Kozarova, Miriam, Hudakova, Terezia, Tkacova, Ruzena, Salagovic, Jan, Tkac, Ivan

“…We aimed to analyse quantitative effects of treatment with sulphonylurea in addition to metformin on parameters of glycemic control in relation to KCNQ1…”
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Relationship between osteoporosis and adipose tissue leptin and osteoprotegerin in patients with chronic obstructive pulmonary disease by Pobeha, Pavol, Ukropec, Jozef, Skyba, Peter, Ukropcova, Barbara, Joppa, Pavol, Kurdiova, Timea, Javorsky, Martin, Klimes, Iwar, Tkac, Ivan, Gasperikova, Daniela, Tkacova, Ruzena

“…Abstract Introduction The role of fat–bone interactions in the pathogenesis of osteoporosis in chronic obstructive pulmonary disease (COPD) is poorly…”
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Lipoprotein lipase HindIII polymorphism influences HDL-cholesterol levels in statin-treated patients with coronary artery disease by Javorský, Martin, Gasperíková, Daniela, Ukropec, Jozef, Sedláková, Barbora, Riecanský, Igor, Krizanová, Ol'ga, Seböková, Elena, Dobríková, Martina, Klimes, Iwar, Tkác, Ivan

“…HDL-cholesterol (HDL-C) is a recognized athero-protective factor and low levels of HDL-C occur frequently in patients with coronary artery disease. Regulation…”
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Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin by Zhou, Kaixin, Yee, Sook Wah, Seiser, Eric L, van Leeuwen, Nienke, Tavendale, Roger, Bennett, Amanda J, Groves, Christopher J, Coleman, Ruth L, van der Heijden, Amber A, Beulens, Joline W, de Keyser, Catherine E, Zaharenko, Linda, Rotroff, Daniel M, Out, Mattijs, Jablonski, Kathleen A, Chen, Ling, Javorský, Martin, Židzik, Jozef, Levin, Albert M, Williams, L Keoki, Dujic, Tanja, Semiz, Sabina, Kubo, Michiaki, Chien, Huan-Chieh, Maeda, Shiro, Witte, John S, Wu, Longyang, Tkáč, Ivan, Kooy, Adriaan, van Schaik, Ron H N, Stehouwer, Coen D A, Logie, Lisa, Sutherland, Calum, Klovins, Janis, Pirags, Valdis, Hofman, Albert, Stricker, Bruno H, Motsinger-Reif, Alison A, Wagner, Michael J, Innocenti, Federico, Hart, Leen M 't, Holman, Rury R, McCarthy, Mark I, Hedderson, Monique M, Palmer, Colin N A, Florez, Jose C, Giacomini, Kathleen M, Pearson, Ewan R

“…Ewan Pearson, Kathleen Giacomini and the Metformin Genetics Consortium perform a genome-wide association study for glycemic response to the antidiabetic drug…”
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