Search Results - "JAVEED ANSARI, M"

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy by Yuan, Xueli, Paez-Cortez, Jesus, Schmitt-Knosalla, Isabela, D'Addio, Francesca, Mfarrej, Bechara, Donnarumma, Michela, Habicht, Antje, Clarkson, Michael R, Iacomini, John, Glimcher, Laurie H, Sayegh, Mohamed H, Ansari, M Javeed

“…T-bet plays a crucial role in Th1 development. We investigated the role of T-bet in the development of allograft rejection in an established MHC class…”
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Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid by Mohamadzadeh, Mansour, Pfeiler, Erika A, Brown, Jeffrey B, Zadeh, Mojgan, Gramarossa, Matthew, Managlia, Elizabeth, Bere, Praveen, Sarraj, Bara, Khan, Mohammad W, Pakanati, Krishna Chaitanya, Ansari, M. Javeed, O'Flaherty, Sarah, Barrett, Terrence, Klaenhammer, Todd R

“…Imbalance in the regulatory immune mechanisms that control intestinal cellular and bacterial homeostasis may lead to induction of the detrimental inflammatory…”
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Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus by Gallon, Lorenzo, Traitanon, Opas, Sustento-Reodica, Nedjema, Leventhal, Joseph, Ansari, M Javeed, Gehrau, Ricardo C, Ariyamuthu, Venkatesh, De Serres, Sacha A, Alvarado, Antonio, Chhabra, Darshika, Mathew, James M, Najafian, Nader, Mas, Valeria

“…Tacrolimus and sirolimus are commonly used maintenance immunosuppressants in kidney transplantation. As their effects on immune cells and allograft molecular…”
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Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection by Sarraj, Bara, Ye, Junsheng, Akl, Ahmed Ibrahim, Chen, Guodong, Wang, Jiao-Jing, Zhang, Zheng, Abadja, Farida, Abecassis, Michael, Miller, Stephen D., Kansas, Geoffrey S., Ansari, M. Javeed

“…Selectin–selectin ligand interactions mediate the initial steps in leukocyte migration, an integral part of immune responses. Fucosyltransferase-VII…”
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Mechanistic analyses in kidney transplant recipients prospectively randomized to two steroid free regimen-Low dose Tacrolimus with Everolimus versus standard dose Tacrolimus with Mycophenolate Mofetil by Traitanon, Opas, Mathew, James M, Shetty, Aneesha, Bontha, Sai Vineela, Maluf, Daniel G, El Kassis, Yvonne, Park, Sook H, Han, Jing, Ansari, M Javeed, Leventhal, Joseph R, Mas, Valeria, Gallon, Lorenzo

“…Calcineurin inhibitors (CNI), the cornerstone of immunosuppression after transplantation are implicated in nephrotoxicity and allograft dysfunction. We…”
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Critical Role of Donor Tissue Expression of Programmed Death Ligand-1 in Regulating Cardiac Allograft Rejection and Vasculopathy by JUN YANG, POPOOLA, Joyce, SHIN, Tahiro, YAGITA, Hideo, AZUMA, Miyuki, SAYEGH, Mohamed H, CHANDRAKER, Anil, KHANDWALA, Shakila, VADIVEL, Nidyanandh, VANGURI, Vijay, XUELI YUAN, DADA, Shirine, GULERIA, Indira, TIAN, Chaorui, JAVEED ANSARI, M

“…Allograft vasculopathy is a major limiting factor in the long-term success of cardiac transplantation. T cells play a critical role in initiation of cardiac…”
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A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice by Vergani, Andrea, D'Addio, Francesca, Jurewicz, Mollie, Petrelli, Alessandra, Watanabe, Toshihiko, Liu, Kaifeng, Law, Kenneth, Schuetz, Christian, Carvello, Michele, Orsenigo, Elena, Deng, Shaoping, Rodig, Scott J, Ansari, Javeed M, Staudacher, Carlo, Abdi, Reza, Williams, John, Markmann, James, Atkinson, Mark, Sayegh, Mohamed H, Fiorina, Paolo

“…To investigate a new clinically relevant immunoregulatory strategy based on treatment with murine Thymoglobulin mATG Genzyme and CTLA4-Ig in NOD mice to…”
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Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells by Yuan, Xueli, Ansari, M. Javeed, D'Addio, Francesca, Paez-Cortez, Jesus, Schmitt, Isabella, Donnarumma, Michela, Boenisch, Olaf, Zhao, Xiaozhi, Popoola, Joyce, Clarkson, Michael R, Yagita, Hideo, Akiba, Hisaya, Freeman, Gordon J, Iacomini, John, Turka, Laurence A, Glimcher, Laurie H, Sayegh, Mohamed H

“…The ability to induce durable transplantation tolerance predictably and consistently in the clinic is a highly desired but elusive goal. Progress is hampered…”
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A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model by D'Addio, Francesca, Yuan, Xueli, Habicht, Antje, Williams, John, Ruzek, Melanie, Iacomini, John, Turka, Laurence A, Sayegh, Mohamed H, Najafian, Nader, Ansari, M Javeed

“…Regulatory T cells (Tregs) actively regulate alloimmune responses and promote transplantation tolerance. Thymoglobulin, a rabbit polyclonal antithymocyte…”
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Heterogeneity of memory B cells by Chong, Anita S., Ansari, M. Javeed

“…Potential solid organ transplant recipients broadly sensitized to HLA have long wait times, low transplant rates and poor outcomes. The new kidney allocation…”
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T-cell exhaustion in allograft rejection and tolerance by Thorp, Edward B., Stehlik, Christian, Ansari, M. Javeed

“…The role of T-cell exhaustion in the failure of clearance of viral infections and tumors is well established. There are several ongoing trials to reverse…”
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The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model by Ueno, Takuya, Habicht, Antje, Clarkson, Michael R, Albin, Monica J, Yamaura, Kazuhiro, Boenisch, Olaf, Popoola, Joyce, Wang, Ying, Yagita, Hideo, Akiba, Hisaya, Ansari, M Javeed, Yang, Jaeseok, Turka, Laurence A, Rothstein, David M, Padera, Robert F, Najafian, Nader, Sayegh, Mohamed H

“…T cell Ig mucin 1 (TIM-1) plays an important role in regulating immune responses in autoimmune and asthma models, and it is expressed on both Th1 and Th2…”
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OR07 by Akl, Ahmed, Roitberg-Tambur, Anat, Javeed Ansari, M

“…Aim T o quantify and characterize HLA-specific B cells subsets identified by single antigen HLA-coated multiplexed beads (SAB) in kidney transplant recipients…”
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Mechanisms Underlying Blockade of Allograft Acceptance by TLR Ligands by Porrett, Paige M, Yuan, Xueli, LaRosa, David F, Walsh, Patrick T, Yang, Jaeseok, Gao, Wenda, Li, Peiying, Zhang, Jidong, Ansari, Javeed M, Hancock, Wayne W, Sayegh, Mohamed H, Koulmanda, Maria, Strom, Terry B, Turka, Laurence A

“…Immune activation via TLRs is known to prevent transplantation tolerance in multiple animal models. To investigate the mechanisms underlying this barrier to…”
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Complement dances with T cells by Ansari, M.Javeed, Sayegh, Mohamed H.

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The arduous road to achieving an immunosuppression-free state in kidney transplant recipients by Sayegh, Mohamed H, Ansari, M Javeed

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Angiotensin II Type 1–Receptor Activating Antibodies in Renal-Allograft Rejection by Hilbrands, Luuk, Hoitsma, Andries, Wetzels, Jack

“…To the Editor: Dragun et al. (Feb. 10 issue) 1 provide provocative data on the role of agonistic angiotensin II type 1 (AT 1 )–receptor antibodies in patients…”
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310.3: Posoleucel as Preemptive Therapy for BKV Infection in Kidney Transplant Recipients: Safety, Tolerability and Efficacy in a Phase 2 Trial by Chandraker, Anil K., Singh, Manpreet, Regmi, Anil, Ansari, M. Javeed, Lonze, Bonnie, Nair, Vinay V., Sharma, Akhil, Knechtle, Stuart J., Cardarelli, Francesca, Marshall, William, Wojciechowski, David

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OR07: A NOVEL MULTIPLEX APPROACH TO DEFINE PERIPHERAL BLOOD HLA-SPECIFIC B-CELL SUBSETS IN CLINICAL TRANSPLANTATION by Akl, Ahmed, Roitberg-Tambur, Anat, Javeed Ansari, M.

“…To quantify and characterize HLA-specific B cells subsets identified by single antigen HLA-coated multiplexed beads (SAB) in kidney transplant recipients. PBMC…”
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Impaired selectin-dependent leukocyte trafficking induces T cell exhaustion and prevents chronic allograft vasculopathy and rejection (P2140) by Sarraj, Bara, Ye, Junsheng, Zhang, Zheng, Miller, Stephen, Kansas, Geoffrey, Ansari, M. Javeed

“…Abstract Selectin-selectin ligand interactions mediate the initial steps in leukocyte emigration, an integral part of immune response. Fucosyltransferase-VII…”
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