Search Results - "JAUZAC, Philippe"

Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells by Kerros, Céline, Cavey, Thibault, Sola, Brigitte, Jauzac, Philippe, Allouche, Stéphane

“…opioid and somatostatin receptors (SSTRs) that can assemble as heterodimer were individually reported to modulate malignant cell proliferation and to favour…”
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Zinc status and bone mineralisation in adolescent girls by Bouglé, Dominique L., Sabatier, Jean-Pierre, Guaydier-Souquières, Geneviève, Guillon-Metz, Françoise, Laroche, Dominique, Jauzac, Philippe, Bureau, François

“…The aim of the project was to assess the relationship between zinc status and bone mineralisation in pre-menarcheal adolescent girls. One hundred and…”
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Potential use of early alterations in μ and δ opioid receptors as a predictive index for delayed brain ischemic damage by Boutin, Hervé, Jauzac, Philippe, MacKenzie, Eric T., Dauphin, François

“…We previously reported differential alterations of the μ, δ, and κ opioid receptors following permanent middle cerebral artery occlusion. The present work…”
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ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands by Aguila, Benjamin, Coulbault, Laurent, Davis, Audrey, Marie, Nicolas, Hasbi, Ahmed, Le bras, Florian, Tóth, Géza, Borsodi, Anna, Gurevich, Vsevolod V., Jauzac, Philippe, Allouche, Stéphane

“…We have previously reported on the differential regulation of the human δ-opioid receptor (hDOR) by alkaloid (etorphine) and peptidic (DPDPE and deltorphin I)…”
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Reduction of cell proliferation and potentiation of Fas-induced apoptosis by the selective kappa-opioid receptor agonist U50 488 in the multiple myeloma LP-1 cells by Kerros, Céline, Brood, Isabelle, Sola, Brigitte, Jauzac, Philippe, Allouche, Stéphane

“…Abstract As opioid receptors modulate proliferation and apoptosis of immune cells, we hypothesized that they could reduce malignant haematopoietic cells. After…”
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Different kinases desensitize the human δ-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists by Marie, Nicolas, Aguila, Benjamin, Hasbi, Ahmed, Davis, Audrey, Jauzac, Philippe, Allouche, Stéphane

“…In a previous work, we described a differential desensitization of the human δ-opioid receptor (hDOP-R) by etorphine (a non-selective and alkaloid agonist) and…”
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Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists by Marie, Nicolas, Lecoq, Isabelle, Jauzac, Philippe, Allouche, Stéphane

“…Desensitization and internalization of G protein-coupled receptors observed after agonist activation are considered two important regulatory processes of…”
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βarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands by Aguila, Benjamin, Coulbault, Laurent, Davis, Audrey, Marie, Nicolas, Hasbi, Ahmed, Le bras, Florian, Tóth, Géza, Borsodi, Anna, Gurevich, Vsevolod V., Jauzac, Philippe, Allouche, Stéphane

“…We have previously reported on the differential regulation of the human δ-opioid receptor (hDOR) by alkaloid (etorphine) and peptidic (DPDPE and deltorphin I)…”
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Long-term alterations in mu, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice by Boutin, Hervé, Catherine, Armelle, Mackenzie, Eric T, Jauzac, Philippe, Dauphin, François

“…Alterations in the opioidergic system may play a role in the molecular mechanisms underlying neurochemical responses to cerebral ischaemia. The present study…”
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High-purity selection and maintenance of gene expression in human neuroblastoma cells stably over-expressing GFP fusion protein Application for opioid receptors desensitization studies by AGUILA, Benjamin, ROUSSEL, Mikel, JAUZAC, Philippe, ALLOUCHE, Stéphane

“…Chronic use of opiates such as morphine is associated with drug tolerance, which is correlated with the desensitization of opioid receptors. This latter…”
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Long-term alterations in [mu], [delta] and [kappa] opioidergic receptors following middle cerebral artery occlusion in mice by Boutin, Hervé, Catherine, Armelle, MacKenzie, Eric T, Jauzac, Philippe, Dauphin, François

“…Alterations in the opioidergic system may play a role in the molecular mechanisms underlying neurochemical responses to cerebral ischaemia. The present study…”
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High-purity selection and maintenance of gene expression in human neuroblastoma cells stably over-expressing GFP fusion protein by Aguila, Benjamin, Roussel, Mikel, Jauzac, Philippe, Allouche, Stéphane

“…Chronic use of opiates such as morphine is associated with drug tolerance, which is correlated with the desensitization of opioid receptors. This latter…”
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Pharmacological characterization of AR-M1000390 at human delta opioid receptors by Marie, Nicolas, Landemore, Gérard, Debout, Claire, Jauzac, Philippe, Allouche, Stéphane

“…We investigated the pharmacological properties of a newly synthesised δ agonist AR-M1000390, derived from SNC-80 ((+)-4-[(alpha…”
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Differential Sorting of Human δ-Opioid Receptors after Internalization by Peptide and Alkaloid Agonists by Nicolas Marie, Isabelle Lecoq, Philippe Jauzac, Stéphane Allouche

“…Desensitization and internalization of G protein-coupled receptors observed after agonist activation are considered two important regulatory processes of…”
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Internalization and recycling of delta-opioid receptor are dependent on a phosphorylation-dephosphorylation mechanism by Hasbi, A, Allouche, S, Sichel, F, Stanasila, L, Massotte, D, Landemore, G, Polastron, J, Jauzac, P

“…Internalization, recycling, and resensitization of the human delta-opioid receptor (hDOR) were studied in the neuroblastoma cell line SK-N-BE, endogenously…”
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Potential use of early alterations in is a subset of and delta opioid receptors as a predictive index for delayed brain ischemic damage by Boutin, Herve, Jauzac, Philippe, MacKenzie, Eric T, Dauphin, Francois

“…We previously reported differential alterations of the is a subset of , delta , and mu opioid receptors following permanent middle cerebral artery occlusion…”
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Differential time-course decreases in nonselective, mu-, delta-, and kappa-opioid receptors after focal cerebral ischemia in mice by Boutin, H, Dauphin, F, MacKenzie, E T, Jauzac, P

“…Neuroprotection studies have demonstrated the involvement of opioids in ischemia, and we have previously demonstrated alterations in Bmax of opioidergic…”
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A novel mutation in the mitochondrial tRNA{sup Asn} gene associated with a lethal disease by Coulbault, Laurent, Herlicoviez, Danielle, Chapon, Francoise, Read, Marie-Helene, Penniello, Marie-Jose, Reynier, Pascal, Fayet, Guillemette, Lombes, Anne, Jauzac, Philippe, Allouche, Stephane

“…We describe a lethal mitochondrial disease in a 10-month-old child who presented with encephalomyopathy. Histochemical and electron microscopy examinations of…”
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Desensitization of the δ‐Opioid Receptor Correlates with Its Phosphorylation in SK‐N‐BE Cells: Involvement of a G Protein‐Coupled Receptor Kinase by Hasbi, Ahmed, Polastron, Jocelyne, Allouche, Stéphane, Stanasila, Laura, Massotte, Dominique, Jauzac, Philippe

“…: Phosphorylation of G protein‐coupled receptors is considered an important step during their desensitization. In SK‐N‐BE cells, recently presented as a…”
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Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE by Allouche, S, Polastron, J, Hasbi, A, Homburger, V, Jauzac, P

“…Differences in the specificity of coupling of delta-opioid receptor with G-protein have been reported in the literature. We have observed a differential…”
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