Search Results - "JANSSENS, Virginie"

Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2 by Johanns, Manuel, Lemoine, Pascale, Janssens, Virginie, Grieco, Giuseppina, Moestrup, Soren K., Nielsen, Rikke, Christensen, Erik I., Courtoy, Pierre J., Emonard, Hervé, Marbaix, Etienne, Henriet, Patrick

“…Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance…”
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163. Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model by Chevronnay, Heloise P. Gaide, Janssens, Virginie, Van Der Smissen, Patrick, Rocca, Celine J., Liao, Xiao-Hui, Refetoff, Samuel, Pierreux, Christophe E., Cherqui, Stephanie, Courtoy, Pierre J.

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Time Course of Pathogenic and Adaptation Mechanisms in Cystinotic Mouse Kidneys by GAIDE CHEVRONNAY, Héloïse P, JANSSENS, Virginie, ANTIGNAC, Corinne, COURTOY, Pierre J, VAN DER SMISSEN, Patrick, N'KULI, Francisca, NEVO, Nathalie, GUIOT, Yves, LEVTCHENKO, Elena, MARBAIX, Etienne, PIERREUX, Christophe E, CHERQUI, Stéphanie

“…Cystinosis, a main cause of Fanconi syndrome, is reproduced in congenic C57BL/6 cystinosin knockout (KO) mice. To identify the sequence of pathogenic and…”
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Protection of Cystinotic Mice by Kidney-Specific Megalin Ablation Supports an Endocytosis-Based Mechanism for Nephropathic Cystinosis Progression by Janssens, Virginie, Gaide Chevronnay, Héloïse P, Marie, Sandrine, Vincent, Marie-Françoise, Van Der Smissen, Patrick, Nevo, Nathalie, Vainio, Seppo, Nielsen, Rikke, Christensen, Erik I, Jouret, François, Antignac, Corinne, Pierreux, Christophe E, Courtoy, Pierre J

“…Deletions or inactivating mutations of the cystinosin gene lead to cystine accumulation and crystals at acidic pH in patients with nephropathic cystinosis, a…”
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Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency by Grieco, Giuseppina, Janssens, Virginie, Gaide Chevronnay, Héloïse P., N’Kuli, Francisca, Van Der Smissen, Patrick, Wang, Tongsong, Shan, Jingdong, Vainio, Seppo, Bilanges, Benoit, Jouret, François, Vanhaesebroeck, Bart, Pierreux, Christophe E., Courtoy, Pierre J.

“…Kidney proximal tubular cells (PTCs) are highly specialized for ultrafiltrate reabsorption and serve as paradigm of apical epithelial differentiation…”
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Class III Phosphoinositide 3‐Kinase/VPS34 and Dynamin are Critical for Apical Endocytic Recycling by Carpentier, Sarah, N'Kuli, Francisca, Grieco, Giuseppina, Van Der Smissen, Patrick, Janssens, Virginie, Emonard, Hervé, Bilanges, Benoît, Vanhaesebroeck, Bart, Gaide Chevronnay, Héloïse P., Pierreux, Christophe E., Tyteca, Donatienne, Courtoy, Pierre J.

“…Synopsis Recycling is a limiting step for receptor‐mediated endocytosis. We here show that class III PI3K is the key isoform involved, based on differential…”
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Clustering of (auto)immune diseases with early-onset and complicated inflammatory bowel disease by Bueno de Mesquita, Mirjam, Ferrante, Marc, Henckaerts, Liesbet, Joossens, Marie, Janssens, Virginie, Hlavaty, Tibor, Pierik, Marie, Joossens, Sofie, Van Schuerbeek, Nele, Van Assche, Gert, Rutgeerts, Paul, Vermeire, Severine, Hoffman, Ilse

“…Studies in adult inflammatory bowel disease (IBD) patients have highlighted associations with genetic and serologic markers and suggest an association with…”
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