Search Results - "JANSON, Esther"

Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects by van Eijk, Kristel R, de Jong, Simone, Boks, Marco P M, Langeveld, Terry, Colas, Fabrice, Veldink, Jan H, de Kovel, Carolien G F, Janson, Esther, Strengman, Eric, Langfelder, Peter, Kahn, René S, van den Berg, Leonard H, Horvath, Steve, Ophoff, Roel A

“…The predominant model for regulation of gene expression through DNA methylation is an inverse association in which increased methylation results in decreased…”
Get full text

The relationship of DNA methylation with age, gender and genotype in twins and healthy controls by Boks, Marco P, Derks, Eske M, Weisenberger, Daniel J, Strengman, Erik, Janson, Esther, Sommer, Iris E, Kahn, René S, Ophoff, Roel A

“…Cytosine-5 methylation within CpG dinucleotides is a potentially important mechanism of epigenetic influence on human traits and disease. In addition to…”
Get full text

Targeted next-generation sequencing: A novel diagnostic tool for primary immunodeficiencies by Nijman, Isaac J., PhD, van Montfrans, Joris M., MD, PhD, Hoogstraat, Marlous, BAS, Boes, Marianne L., PhD, van de Corput, Lisette, PhD, Renner, Ellen D., MD, PhD, van Zon, Patrick, BSc, van Lieshout, Stef, BSc, Elferink, Martin G., PhD, van der Burg, Mirjam, PhD, Vermont, Clementien L., MD, PhD, van der Zwaag, Bert, PhD, Janson, Esther, BSc, Cuppen, Edwin, PhD, Ploos van Amstel, Johannes K., PhD, van Gijn, Marielle E., PhD

“…Background Primary immunodeficiency (PID) disorders are a heterogeneous group of inherited disorders caused by a variety of monogenetic immune defects. Thus…”
Get full text

A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes by de Jong, Simone, Boks, Marco P M, Fuller, Tova F, Strengman, Eric, Janson, Esther, de Kovel, Carolien G F, Ori, Anil P S, Vi, Nancy, Mulder, Flip, Blom, Jan Dirk, Glenthøj, Birte, Schubart, Chris D, Cahn, Wiepke, Kahn, René S, Horvath, Steve, Ophoff, Roel A

“…Despite large-scale genome-wide association studies (GWAS), the underlying genes for schizophrenia are largely unknown. Additional approaches are therefore…”
Get full text

Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner by de Jong, Simone, Chepelev, Iouri, Janson, Esther, Strengman, Eric, van den Berg, Leonard H, Veldink, Jan H, Ophoff, Roel A

“…Chromosome 17q21.31 contains a common inversion polymorphism of approximately 900 kb in populations with European ancestry. Two divergent MAPT haplotypes, H1…”
Get full text

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes by DE JONG, Simone, VAN EIJK, Kristel R, OPHOFF, Roel A, ZEEGERS, Dave W. L. H, STRENGMAN, Eric, JANSON, Esther, VELDINK, Jan H, VAN DEN BERG, Leonard H, CAHN, Wiepke, KAHN, René S, BOKS, Marco P. M

“…There is genetic evidence that schizophrenia is a polygenic disorder with a large number of loci of small effect on disease susceptibility. Genome-wide…”
Get full text

Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia by Forstner, Andreas J., MD, Basmanav, F. Buket, MSc, Mattheisen, Manuel, MD, GROUP Investigators, MSc, Böhmer, Anne C., PhD, Hollegaard, Mads V., BAS, Janson, Esther, MSc, Strengman, Eric, MSc, Priebe, Lutz, MD, Degenhardt, Franziska, PhD, Hoffmann, Per, MSc, Herms, Stefan, MD, Maier, Wolfgang, MD, Mössner, Rainald, MD, Rujescu, Dan, PhD, Ophoff, Roel A., PhD, Moebus, Susanne, MD, DMSc, Mortensen, Preben B., MD, PhD, Børglum, Anders D., MD, DSc, Hougaard, David M., MSc, Frank, Josef, PhD, Witt, Stephanie H., MD, Rietschel, Marcella, PhD, Zimmer, Andreas, MD, Nöthen, Markus M., PhD, Miró, Xavier, PhD, Cichon, Sven

“…Background Schizophrenia is a complex neuropsychiatric disorder of unclear etiology. The strongest known genetic risk factor is the 22q11.2 microdeletion…”
Get full text

Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background by de Jong, Simone, Fuller, Tova F, Janson, Esther, Strengman, Eric, Horvath, Steve, Kas, Martien J H, Ophoff, Roel A

“…We performed gene expression profiling of the amygdala and hippocampus taken from inbred mouse strains C57BL/6J and A/J. The selected brain areas are…”
Get full text

Hippocampal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice by de Jong, Simone, Kas, Martien J H, Kiernan, Jeffrey, de Mooij-van Malsen, Annetrude G, Oppelaar, Hugo, Janson, Esther, Vukobradovic, Igor, Farber, Charles R, Stanford, William L, Ophoff, Roel A

“…In this study, we show that the covariance between behavior and gene expression in the brain can help further unravel the determinants of neurobehavioral…”
Get full text

The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish by Paridaen, Judith T.M.L., Janson, Esther, Utami, Kagistia Hana, Pereboom, Tamara C., Essers, Paul B., van Rooijen, Carina, Zivkovic, Danica, MacInnes, Alyson W.

“…Nucleostemin (NS), a member of a family of nucleolar GTP-binding proteins, is highly expressed in proliferating cells such as stem and cancer cells and is…”
Get full text

A double hit implicates DIAPH3 as an autism risk gene by Vorstman, J A S, van Daalen, E, Jalali, G R, Schmidt, E R E, Pasterkamp, R J, de Jonge, M, Hennekam, E A M, Janson, E, Staal, W G, van der Zwaag, B, Burbach, J P H, Kahn, R S, Emanuel, B S, van Engeland, H, Ophoff, R A

“…Recent studies have shown that more than 10% of autism cases are caused by de novo structural genomic rearrangements. Given that some heritable copy number…”
Get full text

Imaging gene and environmental effects on cerebellum in Attention-Deficit/Hyperactivity Disorder and typical development by de Zeeuw, Patrick, van Belle, Janna, van Dijk, Sarai, Weusten, Juliette, Koeleman, Bobby, Janson, Esther, van Engeland, Herman, Durston, Sarah

“…This study investigates the effects of XKR4, a recently identified candidate gene for Attention-Deficit/Hyperactivity Disorder (ADHD), birth weight, and their…”
Get full text

Season of sampling and season of birth influence serotonin metabolite levels in human cerebrospinal fluid by Luykx, Jurjen J, Bakker, Steven C, Lentjes, Eef, Boks, Marco P M, van Geloven, Nan, Eijkemans, Marinus J C, Janson, Esther, Strengman, Eric, de Lepper, Anne M, Westenberg, Herman, Klopper, Kai E, Hoorn, Hendrik J, Gelissen, Harry P M M, Jordan, Julian, Tolenaar, Noortje M, van Dongen, Eric P A, Michel, Bregt, Abramovic, Lucija, Horvath, Steve, Kappen, Teus, Bruins, Peter, Keijzers, Peter, Borgdorff, Paul, Ophoff, Roel A, Kahn, René S

“…Animal studies have revealed seasonal patterns in cerebrospinal fluid (CSF) monoamine (MA) turnover. In humans, no study had systematically assessed seasonal…”
Get full text

Poster #120 THE GENETICS OF LANGUAGE LATERALIZATION AND LEFT-HANDEDNESS: LINKAGE ANALYSIS IN A DUTCH POPULATION ISOLATE by Somers, Metten, Ophoff, Roel A, Cantor, Rita M, Aukes, Maartje F, van Eijk, Kristel, Dauwan, Meenakshi, van't Slot, Ruben, Janson, Esther, Boks, Marco P, Kahn, René S, Sommer, Iris E

Get full text

Prediction of serotonin transporter promoter polymorphism genotypes from single nucleotide polymorphism arrays using machine learning methods by Lu, Ake Tzu-Hui, Bakker, Steven, Janson, Esther, Cichon, Sven, Cantor, Rita M, Ophoff, Roel A

“…The serotonin transporter gene (SLC6A4) and its promoter (5-HTTLPR) polymorphism have been the focus of a large number of association studies of behavioral…”
Get full text