Search Results - "JANSEN, Henk M"

IL-10 Is an Important Mediator of the Enhanced Susceptibility to Pneumococcal Pneumonia after Influenza Infection by van der Sluijs, Koenraad F, van Elden, Leontine J. R, Nijhuis, Monique, Schuurman, Rob, Pater, Jennie M, Florquin, Sandrine, Goldman, Michel, Jansen, Henk M, Lutter, Rene, van der Poll, Tom

“…Secondary pneumococcal pneumonia is a serious complication during and shortly after influenza infection. We established a mouse model to study postinfluenza…”
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Influenza-Induced Expression of Indoleamine 2,3-Dioxygenase Enhances Interleukin-10 Production and Bacterial Outgrowth during Secondary Pneumococcal Pneumonia by van der Sluijs, Koenraad F., Nijhuis, Monique, Levels, Johannes H. M., Florquin, Sandrine, Mellor, Andrew L., Jansen, Henk M., der Poll, Tom van, Lutter, René

“…BackgroundAirway infection with influenza virus induces local expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO), which has…”
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Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial by Behr, Jürgen, Demedts, Maurits, Buhl, Roland, Costabel, Ulrich, Dekhuijzen, Richard P N, Jansen, Henk M, MacNee, William, Thomeer, Michiel, Wallaert, Benoit, Laurent, Francois, Nicholson, Andrew G, Verbeken, Eric K, Verschakelen, Johny, Flower, C D R, Petruzzelli, Stefano, De Vuyst, Paul, van den Bosch, J M M, Rodriguez-Becerra, Eulogio, Lankhorst, Ida, Sardina, Marco, Boissard, Gabrielle

“…The randomized placebo-controlled IFIGENIA-trial demonstrated that therapy with high-dose N-acetylcysteine (NAC) given for one year, added to prednisone and…”
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Antiinflammatory Effects of Salmeterol after Inhalation of Lipopolysaccharide by Healthy Volunteers by Maris, Nico A, de Vos, Alex F, Dessing, Mark C, Spek, C. Arnold, Lutter, Rene, Jansen, Henk M, van der Zee, Jaring S, Bresser, Paul, van der Poll, Tom

“…Salmeterol is a beta2-adrenoreceptor agonist used in the treatment of obstructive pulmonary disease. Salmeterol inhibits inflammatory responses by neutrophils…”
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Hemodynamic and Clinical Correlates of Endothelin-1 in Chronic Thromboembolic Pulmonary Hypertension by Reesink, Herre J, Meijer, Ronald C, Lutter, René, Boomsma, Frans, Jansen, Henk M, Kloek, Jaap J, Bresser, Paul

“…Background In non-thromboembolic pulmonary hypertension, endothelin (ET)-1 levels are increased and correlate with the hemodynamic severity of the disease…”
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Respiratory Syncytial Virus—Specific CD8+ Memory T Cell Responses in Elderly Persons by de Bree, Godelieve J., Heidema, Jojanneke, van Leeuwen, Ester M. M., van Bleek, Grada M., Jonkers, René E., Jansen, Henk M., van Lier, René A. W., Out, Theo A.

“…Background. We investigated respiratory syncytial virus (RSV)—specific CD8+ memory T cell responses in healthy control participants (n= 31 ) and in patients…”
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Associations between pre-employment immunologic and airway mucosal factors and the development of occupational allergy by Krop, Esmeralda J.M., PhD, Heederik, Dick J.J., PhD, Lutter, René, PhD, de Meer, Gea, MD, PhD, Aalberse, Rob C., PhD, Jansen, Henk M., MD, PhD, van der Zee, Jaring S., MD, PhD

“…Background Sensitization to occupational allergens is frequently found in laboratory animal workers (LAWs) and can cause serious health problems. Atopy is a…”
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Characterization of CD4+ Memory T Cell Responses Directed against Common Respiratory Pathogens in Peripheral Blood and Lung by Daniels, Hans, van Schilfgaarde, Muriel, Jansen, Henk M., Out, Theo A., van Lier, René A. W., Jonkers, René E., de Bree, Godelieve J.

“…Background. We investigated CD4+ memory T cell responses to influenza virus (FLU), respiratory syncytial virus (RSV), and nontypeable Haemophilus influenzae…”
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Antibiotics in Addition to Systemic Corticosteroids for Acute Exacerbations of Chronic Obstructive Pulmonary Disease by Daniels, Johannes M. A, Snijders, Dominic, de Graaff, Casper S, Vlaspolder, Fer, Jansen, Henk M, Boersma, Wim G

“…The role of antibiotics in acute exacerbations is controversial and their efficacy when added to systemic corticosteroids is unknown. We conducted a…”
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Embolization for hemoptysis in chronic thromboembolic pulmonary hypertension: report of two cases and a review of the literature by Reesink, Herre J, van Delden, Otto M, Kloek, Jaap J, Jansen, Henk M, Reekers, Jim A, Bresser, Paul

“…Hemoptysis is a known complication in patients with bronchial artery hypertrophy due to a variety of chronic pulmonary disorders. Bronchial artery hypertrophy…”
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Procalcitonin vs C-reactive protein as predictive markers of response to antibiotic therapy in acute exacerbations of COPD by Daniels, Johannes M A, Schoorl, Marianne, Snijders, Dominic, Knol, Dirk L, Lutter, René, Jansen, Henk M, Boersma, Wim G

“…Rational prescription of antibiotics in acute exacerbations of COPD (AECOPD) requires predictive markers. We aimed to analyze whether markers of systemic…”
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Activation of coagulation and inhibition of fibrinolysis in the lung after inhalation of lipopolysaccharide by healthy volunteers by Maris, Nico A, de Vos, Alex F, Bresser, Paul, van der Zee, Jaring S, Meijers, Joost C, Lijnen, H Roger, Levi, Marcel, Jansen, Henk M, van der Poll, Tom

“…Pneumonia is frequently associated with changes in coagulation and fibrinolysis in the bronchoalveolar space. To determine the effect of lipopolysaccharide…”
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Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro by Fan, Xiao-Yun, van den Berg, Arjen, Snoek, Mieke, van der Flier, Laurens G, Smids, Barbara, Jansen, Henk M, Liu, Rong-Yu, Lutter, René

“…Previously we showed that reduced availability of the essential amino acid tryptophan per se attenuates post-transcriptional control of interleukin (IL)-6 and…”
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High-Dose Acetylcysteine in Idiopathic Pulmonary Fibrosis by Demedts, Maurits, Behr, Juergen, Buhl, Roland, Costabel, Ulrich, Dekhuijzen, Richard, Jansen, Henk M, MacNee, William, Thomeer, Michiel, Wallaert, Benoit, Laurent, François, Nicholson, Andrew G, Verbeken, Eric K, Verschakelen, Johny, Flower, Christopher D.R, Capron, Frédérique, Petruzzelli, Stefano, De Vuyst, Paul, van den Bosch, Jules M.M, Rodriguez-Becerra, Eulogio, Corvasce, Giuseppina, Lankhorst, Ida, Sardina, Marco, Montanari, Mauro

“…Idiopathic pulmonary fibrosis is a progressive disorder characterized by loss of lung function; there is no effective treatment. In this multinational,…”
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Predictors of incorrect inhalation technique in patients with asthma or COPD: a study using a validated videotaped scoring method by Rootmensen, Geert N, van Keimpema, Anton R J, Jansen, Henk M, de Haan, Rob J

“…Inadequate technique reduces the effects of inhalation medication. Errors in inhalation technique have been reported to range up to 85%. Not only various…”
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Repeatability of inflammatory parameters in induced sputum of COPD patients by Boorsma, Martin, Lutter, René, van de Pol, Marianne A, Out, Theo A, Jansen, Henk M, Jonkers, René E

“…Limited information is available on repeatability of inflammatory parameters in whole induced sputum samples from patients with COPD. To study short-term and…”
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Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung by de Bree, Godelieve J, van Leeuwen, Ester M M, Out, Theo A, Jansen, Henk M, Jonkers, René E, van Lier, René A W

“…The lungs are frequently challenged by viruses, and resident CD8(+) T cells likely contribute to the surveillance of these pathogens. To obtain insight into…”
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Limited β2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics by van Veen, Anneke, Wierenga, Eddy A, Westland, Robert, Weller, Frank R, Hart, Guus AM, Jansen, Henk M, Jonkers, René E

“…BACKGROUND: In vitro and some in vivo studies suggested that genetic haplotypes may have an impact on β2-agonist mediated airway responses in asthmatics. Due…”
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Inhalation of β2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract by Maris, Nico A, Florquin, Sandrine, van't Veer, Cornelis, de Vos, Alex F, Buurman, Wim, Jansen, Henk M, van der Poll, Tom

“…BACKGROUND: Nontypable Haemophilus influenzae (NTHi) is a common bacterial pathogen causing human respiratory tract infections under permissive conditions such…”
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E1A expression dysregulates IL-8 production and suppresses IL-6 production by lung epithelial cells by van den Berg, Arjen, Snoek, Mieke, Jansen, Henk M, Lutter, René

“…The adenoviral protein E1A has been proposed to play a role in the pathophysiology of COPD, in particular by increasing IL-8 gene transcription of lung…”
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