Search Results - "JANSEN, Burkhard"

Development and validation of a noninvasive 2-gene molecular assay for cutaneous melanoma by Gerami, Pedram, MD, Yao, Zuxu, PhD, Polsky, David, MD, PhD, Jansen, Burkhard, MD, Busam, Klaus, MD, Ho, Jonhan, MD, Martini, Mary, MD, Ferris, Laura K., MD, PhD

“…Background Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive…”
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Silencing expression of the clusterin/apolipoprotein J gene in human cancer cells using small interfering rna induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress by TROUGAKOS, Ioannis P, SO, Alan, JANSEN, Burkhard, GLEAVE, Martin E, GONOS, Efstathios S

“…Clusterin/Apolipoprotein J (CLU) is a heterodimeric ubiquitously expressed secreted glycoprotein that is implicated in several physiological processes and is…”
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Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness by Gotzmann, Josef, Huber, Heidemarie, Thallinger, Christiane, Wolschek, Markus, Jansen, Burkhard, Schulte-Hermann, Rolf, Beug, Hartmut, Mikulits, Wolfgang

“…In hepatocarcinogenesis, it is an open question whether transforming growth factor (TGF)-β1 provides a tumor-suppressive or a tumor-promoting role. To address…”
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Clusterin and IGFBPs as Antisense Targets in Prostate Cancer by GLEAVE, MARTIN, JANSEN, BURKHARD

“…: The primary hurdle to improved survival of advanced prostate cancer is our failure to prevent or treat the tumor's progression to its lethal and untreatable…”
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bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice by Jansen, Burkhard, Schlagbauer-Wadl, Hermine, Brown, Bob D, Bryan, Robert N, Van Elsas, Andrea, Müller, Markus, Wolff, Klaus, Eichler, Hans-Georg, Pehamberger, Hubert

“…Malignant melanoma is a prime example of cancers that respond poorly to various treatment modalities including chemotherapy. A number of chemotherapeutic…”
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Antisense clusterin oligodeoxynucleotides increase the response of HER-2 gene amplified breast cancer cells to Trastuzumab by Biroccio, Annamaria, D'Angelo, Carmen, Jansen, Burkhard, Gleave, Martin E., Zupi, Gabriella

“…Clusterin (CLU) is a heterodimeric secreted glycoprotein implicated in several physiological and pathological processes including cancer. Although recent data…”
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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c by ROSSE, T, OLIVIER, R, MONNEY, L, RAGER, M, CONUS, S, FELLAY, I, JANSEN, B, BORNER, C

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The Ras Inhibitor S-trans,trans-Farnesylthiosalicylic Acid Chemosensitizes Human Tumor Cells Without Causing Resistance by Gana-Weisz, Mali, Halaschek-Wiener, Julius, Jansen, Burkhard, Elad, Galit, Haklai, Ronit, Kloog, Yoel

“…Ras transformation requires Ras membrane anchorage, which is promoted by a farnesylcysteine carboxymethyl ester and by additional sequences specific to each…”
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Mcl-1 Blocks Radiation-induced Apoptosis and Inhibits Clonogenic Cell Death by SKVARA, Hans, THALLINGER, Christiane, WACHECK, Volker, MONIA, Brett P, PEHAMBERGER, Hubert, JANSEN, Burkhard, SELZER, Edgar

“…Background: Anti-apoptotic Bcl-2 family proteins, such as Bcl-2 and Bcl-x, can modulate radio- and/or chemosensitivity of human malignancies. Since no…”
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52597 Non-invasive gene expression analyses to rule out melanoma in patients with Fitzpatrick skin types IV-VI by Skelsey, Maral, Walker, Michael, Hyde, Mark, Rigby, Andrew, O'Brien, Kaleigh, Clarke, Loren, Jansen, Burkhard

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44163 Pigmented Lesion Assay Performance in Fitzpatrick Phototypes IV- VI by Rock, Jams, Orr, Sarah, Paco, Czarinah, Hill, Kellie, Jansen, Burkhard, Clarke, Loren

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43705 Non-invasive molecular analysis for CTCL detection and differentiation from other skin conditions by Cedeno, Ryan, Rock, James, Allen, Talisha, Clarke, Loren, Jansen, Burkhard, Yao, Zuxu

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52828 Skin cancer risk is increased by somatic mutations detected noninvasively in healthy-appearing sun-exposed skin by Whitaker, John, Kaur, Kulvinder, Ai, Rizi, Perry, Allyson, Riley, Bae, Roberts, Emma, Ibarra, Claudia, Jansen, Burkhard, Clarke, Loren, Stone, Steven

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16184 Risk stratification of severely dysplastic nevi with the use of noninvasively obtained gene expression and mutation analyses by Jackson Cullison, Stephanie R., Yao, Zuxu, LaJolla, CA, Jansen, Burkhard, Ferris, Laura K.

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15335 Real-world utility of a noninvasive gene expression test to rule out primary cutaneous melanoma: A large US registry study by Brouha, Brook, Ferris, Laura K., Skelsey, Maral K., Peck, Gary, Yao, Zuxu, Jansen, Burkhard

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17057 Topical DNA Repair enzyme reversal of UVB-induced gene expression changes by Rosenthal, Amanda, Kolli, Hiren, Moy, Ronald, Rock, James A., Jansen, Burkhard, Yao, Zuxu

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Mcl-1 Is a Novel Therapeutic Target for Human Sarcoma by Thallinger, Christiane, Wolschek, Markus F., Maierhofer, Helmut, Skvara, Hans, Pehamberger, Hubert, Monia, Brett P., Jansen, Burkhard, Wacheck, Volker, Selzer, Edgar

“…Purpose: Little is known about the role that Mcl-1, an antiapoptotic Bcl-2 family member, plays in solid tumor biology and susceptibility to anticancer…”
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An Adhesive Patch-Based Skin Biopsy Device for Molecular Diagnostics and Skin Microbiome Studies by Yao, Zuxu, Moy, Ronald, Allen, Talisha, Jansen, Burkhard

“…A number of diagnoses in clinical dermatology are currently histopathologically confirmed and this image recognition-based confirmation generally requires…”
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Utility of a Noninvasive 2-Gene Molecular Assay for Cutaneous Melanoma and Effect on the Decision to Biopsy by Ferris, Laura K, Jansen, Burkhard, Ho, Jonhan, Busam, Klaus J, Gross, Kenneth, Hansen, Doyle D, Alsobrook, 2nd, John P, Yao, Zuxu, Peck, Gary L, Gerami, Pedram

“…Expression of long intergenic non-protein coding RNA 518 (LINC00518) and preferentially expressed antigen in melanoma (PRAME) genes, obtained via noninvasive…”
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Response to Marchetti et al by Rigel, Darrell S, Whitaker, John W, Skelsey, Maral K, Peck, Gary, Howell, Michael D, Jansen, Burkhard

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