Search Results - "JANIK, J. E"

The toxic and hematologic effects of interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies by Smith, 2nd, J W, Urba, W J, Curti, B D, Elwood, L J, Steis, R G, Janik, J E, Sharfman, W H, Miller, L L, Fenton, R G, Conlon, K C

“…A phase I trial was undertaken because interleukin-1 alpha (IL-1 alpha) possesses antiproliferative, immunostimulatory, antiinfection, myeloprotective, and…”
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Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer by Curti, B D, Ochoa, A C, Powers, G C, Kopp, W C, Alvord, W G, Janik, J E, Gause, B L, Dunn, B, Kopreski, M S, Fenton, R, Zea, A, Dansky-Ullmann, C, Strobl, S, Harvey, L, Nelson, E, Sznol, M, Longo, D L

“…We performed a phase I trial to determine whether in vivo expansion of activated CD4+ T cells was possible in cancer patients. 111Indium labeling was used to…”
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Interstitial pressure of subcutaneous nodules in melanoma and lymphoma patients : changes during treatment by CURTI, B. D, URBA, W. J, ALVORD, W. G, JANIK, J. E, SMITH, J. W, MADARA, K, LONGO, D. L

“…Interstitial pressure (IP) is a physiological variable that may have its greatest influence on the transport of high-molecular-weight therapeutic agents. IP in…”
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Phase I study of subcutaneously administered interleukin-2 in combination with interferon alfa-2a in patients with advanced cancer by Gause, B L, Sznol, M, Kopp, W C, Janik, J E, Smith, 2nd, J W, Steis, R G, Urba, W J, Sharfman, W, Fenton, R G, Creekmore, S P, Holmlund, J, Conlon, K C, VanderMolen, L A, Longo, D L

“…Although high-dose interleukin-2 (IL-2) can produce durable remissions in a subset of responding patients with renal cell carcinoma (RCC), this occurs in the…”
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Short-stay open appendectomy by Janik, J S, Janik, J E

“…This report describes a minimally invasive short-stay open appendectomy technique which improves the length of stay in comparison to traditional open…”
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The Effects of Treatment with Interleukin-1α on Platelet Recovery after High-Dose Carboplatin by Smith, John W, Longo, Dan L, Alvord, W. Gregory, Janik, John E, Sharfman, William H, Gause, Barry L, Curti, Brendan D, Creekmore, Stephen P, Holmlund, Jon T, Fenton, Robert G, Sznol, Mario, Miller, Langdon L, Shimizu, Masanao, Oppenheim, Joost J, Fiem, Shelby J, Hursey, Jean C, Powers, Gerry C, Urba, Walter J

“…Escalation of the dose of many antineoplastic drugs is limited by granulocytopenia and thrombocytopenia. Although colony-stimulating factors 1 , 2 and the…”
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Abrogation of the Hematological and Biological Activities of the Interleukin-3/Granulocyte-Macrophage Colony-Stimulating Factor Fusion Protein PIXY321 by Neutralizing Anti-PIXY321 Antibodies in Cancer Patients Receiving High-Dose Carboplatin by Miller, Langdon L., Korn, Edward L., Stevens, Diane S., Janik, John E., Gause, Barry L., Kopp, William C., Holmlund, Jon T., Curti, Brendan D., Sznol, Mario, Smith, John W., Urba, Walter J., Donegan, Sarah E., Watson, Thelma M., Longo, Dan L.

“…This dose-escalation study was performed to evaluate the hematologic activity, biological effects, immunogenicity, and toxicity of PIXY321 (an…”
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Phase II Trial of Interleukin 1α and Indomethacin in Treatment of Metastatic Melanoma by Janik, John E., Miller, Langdon L., Longo, Dan L., Powers, Geraldine C., Urba, Walter J., Kopp, William C., Gause, Barry L., Curti, Brendan D., Fenton, Robert G., Oppenheim, Joost J., Conlon, Kevin C., Holmlund, Jon T., Sznol, Mario, Sharfman, William H., Steis, Ronald G., Creekmore, Stephen P., Alvord, W. Gregory, Beauchamp, Ann E., Smith, John W.

“…Background: The rising incidence of malignant melanoma and the lack of curative therapies for metastatic disease represent a therapeutic challenge. New agents…”
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Treatment with Tumor Necrosis Factor-α and Granulocyte–Macrophage Colony-Stimulating Factor Increases Epidermal Langerhans' Cell Numbers in Cancer Patients by Janik, John E., Miller, Langdon L., Kopp, William C., Taub, Dennis D., Dawson, Harry, Stevens, Diane, Kostboth, Paige, Curti, Brendan D., Conlon, Kevin C., Dunn, Barbara K., Donegan, Sarah E., Ullrich, Robert, Alvord, W.Gregory, Gause, Barry L., Longo, Dan L.

“…Dendritic cells (DCs) initiate primary and stimulate secondary T-cell responses. We conducted a phase I trial of tumor necrosis factor (TNF-α) and…”
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Efficient synthesis of adeno-associated virus structural proteins requires both adenovirus DNA binding protein and VA I RNA by Janik, J E, Huston, M M, Cho, K, Rose, J A

“…We have shown previously that replication of defective parvoviruses [adeno-associated viruses (AAV)] requires several early adenovirus (Ad) gene products [J…”
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Myositis associated with interleukin-2 therapy in a patient with metastatic renal cell carcinoma by Esteva-Lorenzo, F J, Janik, J E, Fenton, R G, Emslie-Smith, A, Engel, A G, Longo, D L

“…Interleukin-2 (IL-2) has been used successfully in the treatment of some patients with metastatic renal cell carcinoma and melanoma, with a partial response…”
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Erythropoietin production. A potential marker for interleukin-2/interferon-responsive tumors by Janik, J E, Sznol, M, Urba, W J, Figlin, R, Bukowski, R M, Fyfe, G, Pierce, W C, Belldegrun, A, Sharfman, W H, Smith, 2nd, J W

“…Interleukin-2 (IL-2) recently was approved by the Food and Drug Administration for the treatment of renal cell cancer. It is effective in a small minority of…”
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A phase I clinical trial of flavone-8-acetic acid in combination with interleukin 2 by Holmund, J T, Kopp, W C, Wiltrout, R H, Longo, D L, Urba, W J, Janik, J E, Sznol, M, Conlon, K C, Fenton, R G, Hornung, R

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Adeno-associated virus proteins: origin of the capsid components by JANIK, J. E, HUSTON, M. M, ROSE, J. A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Herpes Simplex Virus Types 1 and 2 Completely Help Adenovirus-Associated Virus Replication by Buller, R M, Janik, J E, Sebring, E D, Rose, J A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Anterior exposure of spinal deformities and tumors: A 20-year experience by Janik, Joseph S, Burrington, John D, Janik, James E, Wayne, Eli R, Chang, Jack H.T, Rothenberg, Steven S

“…Data from 505 patients (1976 through 1995) who underwent anterior spinal exposure were retrospectively analyzed. There were 222 boys and 283 girls with a mean…”
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Interleukin 1  Increases Serum Leptin Concentrations in Humans by Janik, J. E.

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A phase II study of carboplatin, cisplatin, interferon-α, and tamoxifen for patients with metastatic melanoma by GAUSE, B. L, SHARFMAN, W. H, JANIK, J. E, CURTI, B. D, RONALD, STEIS, G, URBA, W. J, SMITH, J. W, ALVORD, W. G, ONGO, D. L

“…The purpose of this trial was to determine the toxicity and antineoplastic activity of cisplatin, carboplatin, tamoxifen, and interferon-alpha (IFN-alpha) in…”
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Influence of interleukin-2 regimens on circulating populations of lymphocytes after adoptive transfer of anti-CD3-stimulated T cells: results from a phase I trial in cancer patients by Curti, B D, Ochoa, A C, Urba, W J, Alvord, W G, Kopp, W C, Powers, G, Hawk, C, Creekmore, S P, Gause, B L, Janik, J E, Holmlund, J T, Kremers, P, Fenton, R G, Miller, L, Sznol, M, Smith, 2nd, J W, Sharfman, W H, Longo, D L

“…The adoptive transfer of anti-CD3-stimulated T killer (T-AK) cells was tested with different bolus and infusional interleukin-2 (IL-2) regimens, and anti-CD3…”
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Endocrine effects of IL-1 alpha and beta administered in a phase I trial to patients with advanced cancer by Curti, B D, Urba, W J, Longo, D L, Janik, J E, Sharfman, W H, Miller, L L, Cizza, G, Shimizu, M, Oppenheim, J J, Alvord, W G, Smith, 2nd, J W

“…Previous primate and rodent studies suggested that interleukin-1 alpha (IL-1 alpha) caused changes in the secretion of pituitary, adrenal, thyroid, and gonadal…”
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