Search Results - "JAMSHEDUR RAHMAN, S. M"

xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression by Ji, Xiangming, Qian, Jun, Rahman, S. M. Jamshedur, Siska, Peter J., Zou, Yong, Harris, Bradford K., Hoeksema, Megan D., Trenary, Irina A., Heidi, Chen, Eisenberg, Rosana, Rathmell, Jeffrey C., Young, Jamey D., Massion, Pierre P.

“…Many tumors increase uptake and dependence on glucose, cystine or glutamine. These basic observations on cancer cell metabolism have opened multiple new…”
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Tobacco smoking induces cardiovascular mitochondrial oxidative stress, promotes endothelial dysfunction, and enhances hypertension by Dikalov, Sergey, Itani, Hana, Richmond, Bradley, Vergeade, Aurelia, Rahman, S M Jamshedur, Boutaud, Olivier, Blackwell, Timothy, Massion, Pierre P, Harrison, David G, Dikalova, Anna

“…Tobacco smoking is a major risk factor for cardiovascular disease and hypertension. It is associated with the oxidative stress and induces metabolic…”
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Genomic Underpinnings of Tumor Behavior in In Situ and Early Lung Adenocarcinoma by Qian, Jun, Zhao, Shilin, Zou, Yong, Rahman, S M Jamshedur, Senosain, Maria-Fernanda, Stricker, Thomas, Chen, Heidi, Powell, Charles A, Borczuk, Alain C, Massion, Pierre P

“…We have a limited understanding of the molecular underpinnings of early adenocarcinoma (ADC) progression. We hypothesized that the behavior of early ADC can be…”
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RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers by Qian, Jun, Hassanein, Mohamed, Hoeksema, Megan D., Harris, Bradford K., Zou, Yong, Chen, Heidi, Lu, Pengcheng, Eisenberg, Rosana, Wang, Jing, Espinosa, Allan, Ji, Xiangming, Harris, Fredrick T., Rahman, S. M. Jamshedur, Massion, Pierre P.

“…Aberrant expression of RNA-binding proteins has profound implications for cellular physiology and the pathogenesis of human diseases such as cancer. We…”
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Elucidating the role of EPPK1 in lung adenocarcinoma development by Arimura, Ken, Kammer, Michael, Rahman, S M Jamshedur, Sheau-Chiann, Chen, Zhao, Shilin, Heidi, Chen, Eisenberg, Rosana, Zou, Yong, Antic, Sanja, Richmond, Bradley, Tagaya, Etsuko, Grogan, Eric, Massion, Pierre, Maldonado, Fabien

“…We recently found that epiplakin 1 (EPPK1) alterations were present in 12% of lung adenocarcinoma (LUAD) cases and were associated with a poor prognosis in…”
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Cancer-associated fibroblasts in early-stage lung adenocarcinoma correlate with tumor aggressiveness by Vasiukov, Georgii, Zou, Yong, Senosain, Maria-Fernanda, Rahman, Jamshedur S. M., Antic, Sanja, Young, Katherine M., Grogan, Eric L., Kammer, Michael N., Maldonado, Fabien, Reinhart-King, Cynthia A., Massion, Pierre P.

“…Lung adenocarcinoma (LUAD) is the predominant type of lung cancer in the U.S. and exhibits a broad variety of behaviors ranging from indolent to aggressive…”
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Early Involvement of the Phosphatidylinositol 3-Kinase/Akt Pathway in Lung Cancer Progression by Massion, Pierre P, Taflan, Peter M, Shyr, Yu, Rahman, S. M. Jamshedur, Yildiz, Pinar, Shakthour, Bashar, Edgerton, Mary E, Ninan, Matthew, Andersen, Jeremiah J, Gonzalez, Adriana L

“…Signaling through the phosphatidylinositol 3-kinase (PI3-kinase) pathway has been associated with lung tumorigenesis. We examined the association between gene…”
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The impact of the lung EDRN-CVC on Phase 1, 2, & 3 biomarker validation studies by Kammer, Michael N, Deppen, Stephen A, Antic, Sanja, Jamshedur Rahman, S M, Eisenberg, Rosana, Maldonado, Fabien, Aldrich, Melinda C, Sandler, Kim L, Landman, Bennett, Massion, Pierre P, Grogan, Eric L

“…The Early Detection Research Network's (EDRN) purpose is to discover, develop and validate biomarkers and imaging methods to detect early-stage cancers or…”
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Proteomic Patterns of Preinvasive Bronchial Lesions by Jamshedur Rahman, S. M, Shyr, Yu, Yildiz, Pinar B, Gonzalez, Adriana L, Li, Huiming, Zhang, Xueqiong, Chaurand, Pierre, Yanagisawa, Kiyoshi, Slovis, Bonnie S, Miller, Robert F, Ninan, Mathew, Miller, York E, Franklin, Wilbur A, Caprioli, Richard M, Carbone, David P, Massion, Pierre P

“…A proteomics approach is warranted to further elucidate the molecular steps involved in lung tumor development. We asked whether we could classify preinvasive…”
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Identification of Proteomic Features To Distinguish Benign Pulmonary Nodules from Lung Adenocarcinoma by Codreanu, Simona G, Hoeksema, Megan D, Slebos, Robbert J. C, Zimmerman, Lisa J, Rahman, S. M. Jamshedur, Li, Ming, Chen, Sheau-Chiann, Chen, Heidi, Eisenberg, Rosana, Liebler, Daniel C, Massion, Pierre P

“…We hypothesized that distinct protein expression features of benign and malignant pulmonary nodules may reveal novel candidate biomarkers for the early…”
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Integrative Genomics Analysis Identifies Candidate Drivers at 3q26-29 Amplicon in Squamous Cell Carcinoma of the Lung by JING WANG, JUN QIAN, HOEKSEMA, Megan D, YONG ZOU, ESPINOSA, Allan V, JAMSHEDUR RAHMAN, S. M, BING ZHANG, MASSION, Pierre P

“…Chromosome 3q26-29 is a critical region of genomic amplification in lung squamous cell carcinomas (SCC). Identification of candidate drivers in this region…”
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Acyl-Coenzyme A-Binding Protein Regulates Beta-Oxidation Required for Growth and Survival of Non-Small Cell Lung Cancer by HARRIS, Fredrick T, JAMSHEDUR RAHMAN, S. M, MASSION, Pierre P, HASSANEIN, Mohamed, JUN QIAN, HOEKSEMA, Megan D, HEIDI CHEN, EISENBERG, Rosana, CHAURAND, Pierre, CAPRIOLI, Richard M, SHIOTA, Masakazu

“…We identified acyl-coenzyme A-binding protein (ACBP) as part of a proteomic signature predicting the risk of having lung cancer. Because ACBP is known to…”
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Lung Cancer Diagnosis from Proteomic Analysis of Preinvasive Lesions by JAMSHEDUR RAHMAN, S. M, GONZALEZ, Adriana L, PUTNAM, Joe B, MILLER, York E, FRANKLIN, Wilbur A, BLOT, William J, CARBONE, David P, SHYR, Yu, CAPRIOLI, Richard M, MASSION, Pierre P, MING LI, SEELE, Erin H, ZIMMERMAN, Lisa J, ZHANG, Xueqiong J, MANIER, M. Lisa, OLSON, Sandra J, SHAH, Ronak N, MILLER, Alison N

“…Early detection may help improve survival from lung cancer. In this study, our goal was to derive and validate a signature from the proteomic analysis of…”
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Significance of p63 amplification and overexpression in lung cancer development and prognosis by MASSION, Pierre P, TAFLAN, Peter M, GONZALEZ, Adriana L, JAMSHEDUR RAHMAN, S. M, YILDIZ, Pinar, SHYR, Yu, EDGERTON, Mary E, WESTFALL, Matthew D, ROBERTS, John R, PIETENPOL, Jennifer A, CARBONE, David P

“…The fight against lung cancer is greatly compromised by the lack of effective early detection strategies. Genomic abnormalities and specifically the…”
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In-depth Proteomic Analysis of Nonsmall Cell Lung Cancer to Discover Molecular Targets and Candidate Biomarkers by Kikuchi, Takefumi, Hassanein, Mohamed, Amann, Joseph M., Liu, Qinfeng, Slebos, Robbert J.C., Rahman, S.M. Jamshedur, Kaufman, Jacob M., Zhang, Xueqiong, Hoeksema, Megan D., Harris, Bradford K., Li, Ming, Shyr, Yu, Gonzalez, Adriana L., Zimmerman, Lisa J., Liebler, Daniel C., Massion, Pierre P., Carbone, David P.

“…Advances in proteomic analysis of human samples are driving critical aspects of biomarker discovery and the identification of molecular pathways involved in…”
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Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung by Qian, Jun, Zou, Yong, Rahman, Jamshedur S M, Lu, Bo, Massion, Pierre P

“…Adenocarcinomas of the lung commonly show an increase in the activity of phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway, yet many are resistant to…”
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Validation of a Proteomic Signature of Lung Cancer Risk from Bronchial Specimens of Risk-Stratified Individuals by Rahman, S.M. Jamshedur, Chen, Sheau-Chiann, Wang, Yi-Ting, Gao, Yuqian, Schepmoes, Athena A, Fillmore, Thomas L, Shi, Tujin, Chen, Heidi, Rodland, Karin D, Massion, Pierre P, Grogan, Eric L, Liu, Tao

“…A major challenge in lung cancer prevention and cure hinges on identifying the at-risk population that ultimately develops lung cancer. Previously, we reported…”
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The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer by Rahman, S M Jamshedur, Ji, Xiangming, Zimmerman, Lisa J, Li, Ming, Harris, Bradford K, Hoeksema, Megan D, Trenary, Irina A, Zou, Yong, Qian, Jun, Slebos, Robbert Jc, Beane, Jennifer, Spira, Avrum, Shyr, Yu, Eisenberg, Rosana, Liebler, Daniel C, Young, Jamey D, Massion, Pierre P

“…The molecular determinants of lung cancer risk remain largely unknown. Airway epithelial cells are prone to assault by risk factors and are considered to be…”
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Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer by Yildiz, Pinar B, Shyr, Yu, Rahman, Jamshedur S M, Wardwell, Noel R, Zimmerman, Lisa J, Shakhtour, Bashar, Gray, William H, Chen, Shuo, Li, Ming, Roder, Heinrich, Liebler, Daniel C, Bigbee, William L, Siegfried, Jill M, Weissfeld, Joel L, Gonzalez, Adriana L, Ninan, Mathew, Johnson, David H, Carbone, David P, Caprioli, Richard M, Massion, Pierre P

“…There is a critical need for improvements in the noninvasive diagnosis of lung cancer. We hypothesized that matrix-assisted laser desorption ionization mass…”
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Development of host-dependent high-grade tumor-specific immunity through a novel mechanism triggered by the Lyt-2+ tumor-specific T cell clone (K7L) that induces temporal growth of L1210 leukemia-K7L-variant by Nagase, F, Ueda, K, Kawashima, K, Jamshedur Rahman, SM, Isobe, K, Yoshida, T, Hasegawa, Y, Ando, K, Iwamoto, T, Nagura, E

“…When a murine leukemia L1210-specific Lyt-2+ T cell clone, K7L, was injected i.p. into CD2F1 mice together with L1210, the normal growth of L1210 in the…”
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