Search Results - "JAMA ophthalmology"

Automated Grading of Age-Related Macular Degeneration From Color Fundus Images Using Deep Convolutional Neural Networks by Burlina, Philippe M, Joshi, Neil, Pekala, Michael, Pacheco, Katia D, Freund, David E, Bressler, Neil M

“…Age-related macular degeneration (AMD) affects millions of people throughout the world. The intermediate stage may go undetected, as it typically is…”
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Global Survey of Corneal Transplantation and Eye Banking by Gain, Philippe, Jullienne, Rémy, He, Zhiguo, Aldossary, Mansour, Acquart, Sophie, Cognasse, Fabrice, Thuret, Gilles

“…Corneal transplantation restores visual function when visual impairment caused by a corneal disease becomes too severe. It is considered the world's most…”
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Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography by Spaide, Richard F, Klancnik, Jr, James M, Cooney, Michael J

“…The retinal vasculature is involved in many ocular diseases that cause visual loss. Although fluorescein angiography is the criterion standard for evaluating…”
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Five-Year Outcomes of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial by Gross, Jeffrey G, Glassman, Adam R, Liu, Danni, Sun, Jennifer K, Antoszyk, Andrew N, Baker, Carl W, Bressler, Neil M, Elman, Michael J, Ferris, 3rd, Frederick L, Gardner, Thomas W, Jampol, Lee M, Martin, Daniel F, Melia, Michele, Stockdale, Cynthia R, Beck, Roy W

“…Ranibizumab is a viable treatment option for eyes with proliferative diabetic retinopathy (PDR) through 2 years. However, longer-term results are needed. To…”
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Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma by Liu, Liang, Jia, Yali, Takusagawa, Hana L, Pechauer, Alex D, Edmunds, Beth, Lombardi, Lorinna, Davis, Ellen, Morrison, John C, Huang, David

“…Vascular factors may have important roles in the pathophysiology of glaucoma. A practical method for the clinical evaluation of ocular perfusion is needed to…”
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Efficacy and Safety of Ranibizumab With or Without Verteporfin Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: A Randomized Clinical Trial by Koh, Adrian, Lai, Timothy Y Y, Takahashi, Kanji, Wong, Tien Y, Chen, Lee-Jen, Ruamviboonsuk, Paisan, Tan, Colin S, Feller, Chrystel, Margaron, Philippe, Lim, Tock H, Lee, Won Ki

“…Polypoidal choroidal vasculopathy (PCV) is a common subtype of exudative age-related macular degeneration among Asian individuals. To our knowledge, there are…”
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The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy by Melles, Ronald B, Marmor, Michael F

“…Hydroxychloroquine sulfate is widely used for the long-term treatment of autoimmune conditions but can cause irreversible toxic retinopathy. Prior estimations…”
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Quantification of Retinal Microvascular Density in Optical Coherence Tomographic Angiography Images in Diabetic Retinopathy by Durbin, Mary K, An, Lin, Shemonski, Nathan D, Soares, Mário, Santos, Torcato, Lopes, Marta, Neves, Catarina, Cunha-Vaz, Jose

“…Quantitative measurements based on optical coherence tomographic angiography (OCTA) may have value in managing diabetic retinopathy (DR), but there is limited…”
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Automated Quantification of Capillary Nonperfusion Using Optical Coherence Tomography Angiography in Diabetic Retinopathy by Hwang, Thomas S, Gao, Simon S, Liu, Liang, Lauer, Andreas K, Bailey, Steven T, Flaxel, Christina J, Wilson, David J, Huang, David, Jia, Yali

“…Macular ischemia is a key feature of diabetic retinopathy (DR). Quantification of macular ischemia has potential as a biomarker for DR. To assess the…”
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Visual Impairment and Blindness in Adults in the United States: Demographic and Geographic Variations From 2015 to 2050 by Varma, Rohit, Vajaranant, Thasarat S, Burkemper, Bruce, Wu, Shuang, Torres, Mina, Hsu, Chunyi, Choudhury, Farzana, McKean-Cowdin, Roberta

“…The number of individuals with visual impairment (VI) and blindness is increasing in the United States and around the globe as a result of shifting…”
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Association of Vision Loss With Cognition in Older Adults by Chen, Stephanie P, Bhattacharya, Jay, Pershing, Suzann

“…Visual dysfunction and poor cognition are highly prevalent among older adults; however, the relationship is not well defined. To evaluate the association of…”
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Disorganization of the retinal inner layers as a predictor of visual acuity in eyes with center-involved diabetic macular edema by Sun, Jennifer K, Lin, Michael M, Lammer, Jan, Prager, Sonja, Sarangi, Rutuparna, Silva, Paolo S, Aiello, Lloyd Paul

“…Biomarkers that predict future visual acuity (VA) in eyes with baseline diabetic macular edema (DME) would substantively improve risk assessment, management…”
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Repeatability and Reproducibility of Superficial Macular Retinal Vessel Density Measurements Using Optical Coherence Tomography Angiography En Face Images by Lei, Jianqin, Durbin, Mary K, Shi, Yue, Uji, Akihito, Balasubramanian, Siva, Baghdasaryan, Elmira, Al-Sheikh, Mayss, Sadda, Srinivas R

“…The repeatability and reproducibility of quantitative metrics from optical coherence tomographic angiography (OCTA) must be assessed before these data can be…”
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Association of Axial Length With Risk of Uncorrectable Visual Impairment for Europeans With Myopia by Tideman, J Willem L, Snabel, Margaretha C C, Tedja, Milly S, van Rijn, Gwyneth A, Wong, King T, Kuijpers, Robert W A M, Vingerling, Johannes R, Hofman, Albert, Buitendijk, Gabriëlle H S, Keunen, Jan E E, Boon, Camiel J F, Geerards, Annette J M, Luyten, Gregorius P M, Verhoeven, Virginie J M, Klaver, Caroline C W

“…Myopia (ie, nearsightedness) is becoming the most common eye disorder to cause blindness in younger persons in many parts of the world. Visual impairment due…”
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Efficacy and Adverse Effects of Atropine in Childhood Myopia: A Meta-analysis by Gong, Qianwen, Janowski, Miroslaw, Luo, Mi, Wei, Hong, Chen, Bingjie, Yang, Guoyuan, Liu, Longqian

“…Some uncertainty about the clinical value and dosing of atropine for the treatment of myopia in children remains. To evaluate the efficacy vs the adverse…”
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Evaluation of Intravitreal Aflibercept for the Treatment of Severe Nonproliferative Diabetic Retinopathy: Results From the PANORAMA Randomized Clinical Trial by Brown, David M, Wykoff, Charles C, Boyer, David, Heier, Jeffrey S, Clark, W Lloyd, Emanuelli, Andres, Higgins, Patrick M, Singer, Michael, Weinreich, David M, Yancopoulos, George D, Berliner, Alyson J, Chu, Karen, Reed, Kimberly, Cheng, Yenchieh, Vitti, Robert

“…Proactive treatment of nonproliferative diabetic retinopathy (NPDR) reduces the risk of progression to vision-threatening complications. To evaluate vascular…”
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Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28 by Chew, Emily Y, Clemons, Traci E, Agrón, Elvira, Domalpally, Amitha, Keenan, Tiarnán D L, Vitale, Susan, Weber, Claire, Smith, Douglas C, Christen, William

“…After the Age-Related Eye Disease Study 2 (AREDS2) study, the beta carotene component was replaced by lutein/zeaxanthin for the development of the revised…”
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Epidemiology of Eye-Related Emergency Department Visits by Channa, Roomasa, Zafar, Syed Nabeel, Canner, Joseph K, Haring, R Sterling, Schneider, Eric B, Friedman, David S

“…Determining the epidemiology of eye-related emergency department (ED) visits on a national level can assist policymakers in appropriate allocation of…”
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Prevalence of and risk factors for diabetic macular edema in the United States by Varma, Rohit, Bressler, Neil M, Doan, Quan V, Gleeson, Michelle, Danese, Mark, Bower, Julie K, Selvin, Elizabeth, Dolan, Chantal, Fine, Jennifer, Colman, Shoshana, Turpcu, Adam

“…Diabetic macular edema (DME) is a leading cause of vision loss in persons with diabetes mellitus. Although there are national estimates for the prevalence of…”
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Driver Mutations in Uveal Melanoma: Associations With Gene Expression Profile and Patient Outcomes by Decatur, Christina L, Ong, Erin, Garg, Nisha, Anbunathan, Hima, Bowcock, Anne M, Field, Matthew G, Harbour, J William

“…Frequent mutations have been described in the following 5 genes in uveal melanoma (UM): BAP1, EIF1AX, GNA11, GNAQ, and SF3B1. Understanding the prognostic…”
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