Search Results - "JAHN, LINDA"
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Metformin improves skeletal muscle microvascular insulin resistance in metabolic syndrome
Published in American journal of physiology: endocrinology and metabolism (01-02-2022)“…Microvascular insulin resistance is present in metabolic syndrome and may contribute to increased cardiovascular disease risk and the impaired metabolic…”
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Indole-3-Acetic Acid Is Synthesized by the Endophyte Cyanodermella asteris via a Tryptophan-Dependent and -Independent Way and Mediates the Interaction with a Non-Host Plant
Published in International journal of molecular sciences (06-03-2021)“…The plant hormone indole-3-acetic acid (IAA) is one of the main signals playing a role in the communication between host and endophytes. Endophytes can…”
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Impact of Free Fatty Acids on Vascular Insulin Responses Across the Arterial Tree: A Randomized Crossover Study
Published in The journal of clinical endocrinology and metabolism (15-03-2024)“…Abstract Context Vascular insulin resistance is commonly observed in obesity and diabetes; yet, insulin action across the vascular tree and the relationship…”
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GLP-1 at physiological concentrations recruits skeletal and cardiac muscle microvasculature in healthy humans
Published in Clinical science (1979) (01-08-2014)“…Muscle microvascular surface area determines substrate and hormonal exchanges between plasma and muscle interstitium. GLP-1 (glucagon-like peptide-1) regulates…”
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5
Empagliflozin improves vascular insulin sensitivity and muscle perfusion in persons with type 2 diabetes
Published in American journal of physiology: endocrinology and metabolism (01-03-2024)“…Sodium glucose cotransporter 2 inhibitors (SGLT2is) improved major adverse cardiovascular events (MACE), heart failure, and renal outcomes in large trials;…”
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Acute hyperglycaemia enhances both vascular endothelial function and cardiac and skeletal muscle microvascular function in healthy humans
Published in The Journal of physiology (01-02-2022)“…Key points Multiple clinical studies report that acute hyperglycaemia (induced by mixed meal or oral glucose) decreases arterial vascular function in healthy…”
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Vasodilatory Actions of Glucagon-Like Peptide 1 Are Preserved in Skeletal and Cardiac Muscle Microvasculature but Not in Conduit Artery in Obese Humans With Vascular Insulin Resistance
Published in Diabetes care (01-03-2020)“…Obesity is associated with microvascular insulin resistance, which is characterized by impaired insulin-mediated microvascular recruitment. Glucagon-like…”
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Insulin Enhances Endothelial Function Throughout the Arterial Tree in Healthy But Not Metabolic Syndrome Subjects
Published in The journal of clinical endocrinology and metabolism (01-03-2016)“…Context: Insulin reportedly impairs endothelial function in conduit arteries but improves it in resistance and microvascular arterioles in healthy humans. No…”
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Insulin-mediated muscle microvascular perfusion and its phenotypic predictors in humans
Published in Scientific reports (01-06-2021)“…Insulin increases muscle microvascular perfusion and enhances tissue insulin and nutrient delivery. Our aim was to determine phenotypic traits that foretell…”
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Insulin-induced vasoconstriction is prevalent in muscle microvasculature of otherwise healthy persons with type 1 diabetes
Published in American journal of physiology: endocrinology and metabolism (01-05-2023)“…Insulin's microvascular actions and their relationship to insulin's metabolic actions have not been well studied in adults with type 1 diabetes mellitus…”
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Nitric oxide-dependent micro- and macrovascular dysfunction occurs early in adolescents with type 1 diabetes
Published in American journal of physiology: endocrinology and metabolism (01-02-2022)“…Arterial stiffness and endothelial dysfunction are both reported in children with type 1 diabetes (DM1) and may predict future cardiovascular events. In…”
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Free Fatty Acids Induce Insulin Resistance in Both Cardiac and Skeletal Muscle Microvasculature in Humans
Published in The journal of clinical endocrinology and metabolism (01-02-2011)“…Free fatty acids induce insulin resistance in both cardiac and skeletal muscle microvasculature in humans, which may contribute to cardiac complications and…”
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Infusing Lipid Raises Plasma Free Fatty Acids and Induces Insulin Resistance in Muscle Microvasculature
Published in The journal of clinical endocrinology and metabolism (01-09-2009)“…Context: Insulin recruits muscle microvasculature, which increases the endothelial exchange surface area to facilitate substrate delivery. Elevated plasma…”
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Obesity Blunts Insulin-Mediated Microvascular Recruitment in Human Forearm Muscle
Published in Diabetes (New York, N.Y.) (01-05-2006)“…Obesity Blunts Insulin-Mediated Microvascular Recruitment in Human Forearm Muscle Lucy H. Clerk , Michelle A. Vincent , Linda A. Jahn , Zhenqi Liu , Jonathan…”
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15
Obesity Blunts Microvascular Recruitment in Human Forearm Muscle After a Mixed Meal
Published in Diabetes care (01-09-2009)“…OBJECTIVE: Ingestion of a mixed meal recruits flow to muscle capillaries and increases total forearm blood flow in healthy young lean people. We examined…”
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The Endophytic Fungus Cyanodermella asteris Influences Growth of the Nonnatural Host Plant Arabidopsis thaliana
Published in Molecular plant-microbe interactions (01-01-2022)“…is a fungal endophyte from , a perennial plant from the northern part of Asia. Here, we demonstrated an interaction of with , Chinese cabbage, rapeseed,…”
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Mixed meal and light exercise each recruit muscle capillaries in healthy humans
Published in American journal of physiology: endocrinology and metabolism (01-06-2006)“…Intense exercise and insulin each increases total limb blood flow and recruits muscle capillaries, presumably to facilitate nutrient exchange. Whether mixed…”
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Insulin increases central aortic stiffness in response to hyperglycemia in healthy humans: A randomized four-arm study
Published in Diabetes & vascular disease research (01-03-2021)“…Introduction: Increasing arterial stiffness is a feature of vascular aging that is accelerated by conditions that enhance cardiovascular risk, including…”
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Salsalate Attenuates Free Fatty Acid-Induced Microvascular and Metabolic Insulin Resistance in Humans
Published in Diabetes care (01-07-2011)“…OBJECTIVE: Insulin recruits muscle microvasculature, thereby increasing endothelial exchange surface area. Free fatty acids (FFAs) cause insulin resistance by…”
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Hyperinsulinemia Rapidly Increases Human Muscle Microvascular Perfusion but Fails to Increase Muscle Insulin Clearance : Evidence That a Saturable Process Mediates Muscle Insulin Uptake
Published in Diabetes (New York, N.Y.) (01-12-2007)“…Transport of insulin from the central circulation into muscle is rate limiting for the stimulation of glucose metabolism. By recruiting muscle…”
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