Search Results - "JAGGI, Rolf"

MIQE précis: Practical implementation of minimum standard guidelines for fluorescence-based quantitative real-time PCR experiments by Bustin, Stephen A, Beaulieu, Jean-François, Huggett, Jim, Jaggi, Rolf, Kibenge, Frederick S B, Olsvik, Pål A, Penning, Louis C, Toegel, Stefan

“…The conclusions of thousands of peer-reviewed publications rely on data obtained using fluorescence-based quantitative real-time PCR technology. However, the…”
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Molecular characterization of breast cancer cell pools with normal or reduced ability to respond to progesterone: a study based on RNA-seq by Bustamante Eduardo, Mariana, Keller, Irene, Schuster, Nathalie, Aebi, Stefan, Jaggi, Rolf

“…Background About one-third of patients with estrogen receptor alpha (ER[alpha])-positive breast cancer have tumors which are progesterone receptor (PR)…”
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KPNA2 Expression Is an Independent Adverse Predictor of Biochemical Recurrence after Radical Prostatectomy by MORTEZAVI, Ashkan, HERMANNS, Thomas, HARTMANN, Arndt, JAGGI, Rolf, MOCH, Holger, KRISTIANSEN, Glen, WILD, Peter J, SEIFERT, Hans-Helge, BAUMGARTNER, Martin K, PROVENZANO, Maurizio, SULSER, Tullio, BURGER, Maximilian, MONTANI, Matteo, IKENBERG, Kristian, HOFSTÄDTER, Ferdinand

“…To analyze rates of expression of karyopherin alpha 2 (KPNA2) in different prostate tissues and to evaluate the prognostic properties for patients with primary…”
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Characterization of molecular scores and gene expression signatures in primary breast cancer, local recurrences and brain metastases by Bustamante Eduardo, Mariana, Popovici, Vlad, Imboden, Sara, Aebi, Stefan, Ballabio, Nadja, Altermatt, Hans Jörg, Günthert, Andreas, Jaggi, Rolf

“…Breast cancer is a leading cause of cancer-related death in women worldwide. Despite extensive studies in all areas of basic, clinical and applied research,…”
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Selecting control genes for RT-QPCR using public microarray data by Popovici, Vlad, Goldstein, Darlene R, Antonov, Janine, Jaggi, Rolf, Delorenzi, Mauro, Wirapati, Pratyaksha

“…Gene expression analysis has emerged as a major biological research area, with real-time quantitative reverse transcription PCR (RT-QPCR) being one of the most…”
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Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs by Gottstein, Bruno, Wittwer, Matthias, Schild, Marc, Merli, Michael, Leib, Stephen L, Müller, Norbert, Müller, Joachim, Jaggi, Rolf

“…Alveolar echinococcosis (AE) is a severe chronic hepatic parasitic disease currently emerging in central and eastern Europe. Untreated AE presents a high…”
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Expression profiling with RNA from formalin-fixed, paraffin-embedded material by Oberli, Andrea, Popovici, Vlad, Delorenzi, Mauro, Baltzer, Anna, Antonov, Janine, Matthey, Sybille, Aebi, Stefan, Altermatt, Hans Jörg, Jaggi, Rolf

“…Molecular characterization of breast and other cancers by gene expression profiling has corroborated existing classifications and revealed novel subtypes. Most…”
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Gene expression variation between distinct areas of breast cancer measured from paraffin-embedded tissue cores by Schobesberger, Martina, Baltzer, Anna, Oberli, Andrea, Kappeler, Andreas, Gugger, Mathias, Burger, Hana, Jaggi, Rolf

“…Diagnosis and prognosis in breast cancer are mainly based on histology and immunohistochemistry of formalin-fixed, paraffin-embedded (FFPE) material. Recently,…”
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Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue by Antonov, Janine, Popovici, Vlad, Delorenzi, Mauro, Wirapati, Pratyaksha, Baltzer, Anna, Oberli, Andrea, Thürlimann, Beat, Giobbie-Hurder, Anita, Viale, Giuseppe, Altermatt, Hans Jörg, Aebi, Stefan, Jaggi, Rolf

“…The purpose of the work reported here is to test reliable molecular profiles using routinely processed formalin-fixed paraffin-embedded (FFPE) tissues from…”
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Transcription Factor NFIC Undergoes N-Glycosylation during Early Mammary Gland Involution by Kane, Rosemary, Murtagh, Janice, Finlay, Darren, Marti, Andreas, Jaggi, Rolf, Blatchford, David, Wilde, Colin, Martin, Finian

“…Expression of a 74-kDa nuclear factor I (NFI) protein is triggered in early involution in the mouse mammary gland, and its expression correlates with enhanced…”
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Apoptosis during castration-induced regression of the prostate is Fos dependent by ZHIWEI FENG, JOOS, H. J, VALLAN, C, MÜHLBAUER, R, ALTERMATT, H. J, JAGGI, R

“…Apoptotic cell death was shown to be accompanied or preceded by an elevated expression of the c-fos protooncogene and DNA binding activity of transcription…”
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The need for transparency and good practices in the qPCR literature by Bustin, Stephen A, Benes, Vladimir, Garson, Jeremy, Hellemans, Jan, Huggett, Jim, Kubista, Mikael, Mueller, Reinhold, Nolan, Tania, Pfaffl, Michael W, Shipley, Gregory, Wittwer, Carl T, Schjerling, Peter, Day, Philip J, Abreu, Mónica, Aguado, Begoña, Beaulieu, Jean-François, Beckers, Anneleen, Bogaert, Sara, Browne, John A, Carrasco-Ramiro, Fernando, Ceelen, Liesbeth, Ciborowski, Kate, Cornillie, Pieter, Coulon, Stephanie, Cuypers, Ann, De Brouwer, Sara, De Ceuninck, Leentje, De Craene, Jurgen, De Naeyer, Hélène, De Spiegelaere, Ward, Deckers, Kato, Dheedene, Annelies, Durinck, Kaat, Ferreira-Teixeira, Margarida, Fieuw, Annelies, Gallup, Jack M, Gonzalo-Flores, Sandra, Goossens, Karen, Heindryckx, Femke, Herring, Elizabeth, Hoenicka, Hans, Icardi, Laura, Jaggi, Rolf, Javad, Farzad, Karampelias, Michael, Kibenge, Frederick, Kibenge, Molly, Kumps, Candy, Lambertz, Irina, Lammens, Tim, Markey, Amelia, Messiaen, Peter, Mets, Evelien, Morais, Sofia, Mudarra-Rubio, Alberto, Nakiwala, Justine, Nelis, Hilde, Olsvik, Pal A, Pérez-Novo, Claudina, Plusquin, Michelle, Remans, Tony, Rihani, Ali, Rodrigues-Santos, Paulo, Rondou, Pieter, Sanders, Rebecca, Schmidt-Bleek, Katharina, Skovgaard, Kerstin, Smeets, Karen, Tabera, Laura, Toegel, Stefan, Van Acker, Tim, Van den Broeck, Wim, Van der Meulen, Joni, Van Gele, Mireille, Van Peer, Gert, Van Poucke, Mario, Van Roy, Nadine, Vergult, Sarah, Wauman, Joris, Tshuikina-Wiklander, Marina, Willems, Erik, Zaccara, Sara, Zeka, Fjoralba, Vandesompele, Jo

“…Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of…”
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The tunel assay in the diagnosis of graft-versus-host disease: caveats for interpretation by Jerome, Keith R., Vallan, Claudio, Jaggi, Rolf

“…Acute graft-versus-host disease (GVHD) is a significant cause of morbidity and mortality following bone marrow transplantation, and early detection is…”
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Joint analysis of histopathology image features and gene expression in breast cancer by Popovici, Vlad, Budinská, Eva, Čápková, Lenka, Schwarz, Daniel, Dušek, Ladislav, Feit, Josef, Jaggi, Rolf

“…Genomics and proteomics are nowadays the dominant techniques for novel biomarker discovery. However, histopathology images contain a wealth of information…”
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MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma by Rothschild, Sacha I, Tschan, Mario P, Jaggi, Rolf, Fey, Martin F, Gugger, Mathias, Gautschi, Oliver

“…MicroRNAs are small, noncoding RNAs that suppress gene expression by binding to the 3' untranslated region (UTR) and thereby repress translation or decrease…”
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Efficacy of Cetuximab in Metastatic Castration-Resistant Prostate Cancer Might Depend on EGFR and PTEN Expression: Results from a Phase II Trial (SAKK 08/07) by CATHOMAS, Richard, ROTHERMUNDT, Christian, SICILIANO, Daniele, BERTHOLD, Dominik R, PLESS, Miklos, SCHIESS, Ralph, MOOS, Roger Von, GILLESSEN, Silke, KLINGBIEL, Dirk, BUBENDORF, Lukas, JAGGI, Rolf, BETTICHER, Daniel C, BRAUCHLI, Peter, COTTING, Denise, DROEGE, Cornelia, WINTERHALDER, Ralph

“…The EGF receptor (EGFR) is overexpressed in the majority of metastatic castration-resistant prostate cancers (mCRPC) and might represent a valid therapeutic…”
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Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization by ANTONOV, Janine, GOLDSTEIN, Darlene R, OBERLI, Andrea, BALTZER, Anna, PIROTTA, Marco, FLEISCHMANN, Achim, ALTERMATT, Hails J, JAGGI, Rolf

“…Quantitative reverse transcriptase real-time PCR (QRT-PCR) is a robust method to quantitate RNA abundance. The procedure is highly sensitive and reproducible…”
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The homeobox gene HLXB9 is upregulated in a morphological subset of poorly differentiated hepatocellular carcinoma by Wilkens, Ludwig, Jaggi, Rolf, Hammer, Caroline, Inderbitzin, Daniel, Giger, Olivier, von Neuhoff, Nils

“…The prognostic outcome for hepatocellular carcinoma (HCC) remains poor. Disease progression is accompanied by dedifferentiation of the carcinoma, a process…”
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Sequence Capture and Next-Generation Resequencing of Multiple Tagged Nucleic Acid Samples for Mutation Screening of Urea Cycle Disorders by AMSTUTZ, Ursula, ANDREY-ZÜRCHER, Gisela, SUCIU, Dominic, JAGGI, Rolf, HÄBERLE, Johannes, LARGIADER, Carlo R

“…Molecular genetic testing is commonly used to confirm clinical diagnoses of inherited urea cycle disorders (UCDs); however, conventional mutation screenings…”
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Abstract 3987: Src regulates inhibitor of differentiation 1 (Id1) via c-Myc induced repression of microRNA-29b: Implications for invasion of lung cancer cells and their resistance against Src inhibitors by Rothschild, Sacha I., Tschan, Mario P., Jaggi, Rolf, Fey, Martin F., Gugger, Mathias, Gautschi, Oliver

“…Background: Src and Id1 mediate cancer cell invasion and are frequently co-expressed in non-small cell lung cancer (NSCLC). We previously demonstrated that Src…”
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