Search Results - "JAGADEESWARAN, Sujatha"

Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via α5-Integrin, which Is a Therapeutic Target by SAWADA, Kenjiro, MITRA, Anirban K, PETER, Marcus E, RAMAKRISHNAN, Vanitha, YAMADA, S. Diane, LENGYEL, Ernst, REZA RADJABI, A, BHASKAR, Vinay, KISTNER, Emily O, TRETIAKOVA, Maria, JAGADEESWARAN, Sujatha, MONTAG, Anthony, BECKER, Amy, KENNY, Hilary A

“…Abstract E-cadherin loss is frequently associated with ovarian cancer metastasis. Given that adhesion to the abdominal peritoneum is the first step in ovarian…”
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The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia by Pappano, William N, Guo, Jun, He, Yupeng, Ferguson, Debra, Jagadeeswaran, Sujatha, Osterling, Donald J, Gao, Wenqing, Spence, Julie K, Pliushchev, Marina, Sweis, Ramzi F, Buchanan, Fritz G, Michaelides, Michael R, Shoemaker, Alexander R, Tse, Chris, Chiang, Gary G

“…Histone methyltransferases are epigenetic regulators that modify key lysine and arginine residues on histones and are believed to play an important role in…”
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Thrombin Induces Tumor Invasion through the Induction and Association of Matrix Metalloproteinase-9 and β1-Integrin on the Cell Surface by Radjabi, A. Reza, Sawada, Kenjiro, Jagadeeswaran, Sujatha, Eichbichler, Alfred, Kenny, Hilary A., Montag, Anthony, Bruno, Katharina, Lengyel, Ernst

“…The procoagulatory serine protease, thrombin, is known to induce invasion and metastasis in various cancers, but the mechanisms by which it promotes…”
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Functional analysis of c-met/hepatocyte growth factor pathway in malignant pleural mesothelioma by JAGADEESWARAN, Ramasamy, MA, Patrick C, KRATZKE, Robert A, GORDON, Gavin J, SUGARBAKER, David J, BUENO, Raphael, JANAMANCHI, Varalakshmi, BINDOKAS, Vytas P, KINDLER, Hedy L, SALGIA, Ravi, SEIWERT, Tanguy Y, JAGADEESWARAN, Sujatha, ZUMBA, Osvaldo, NALLASURA, Vidya, AHMED, Salman, FILIBERTI, Rosangela, PAGANUZZI, Michela, PUNTONI, Riccardo

“…c-Met receptor tyrosine kinase (RTK) has not been extensively studied in malignant pleural mesothelioma (MPM). In this study, c-Met was overexpressed and…”
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Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells by Jagadeeswaran, Ramasamy, Jagadeeswaran, Sujatha, Bindokas, Vytas P, Salgia, Ravi

“…Small cell lung cancer (SCLC) is a difficult disease to treat and sometimes has overexpression or mutation of c-Met receptor tyrosine kinase. The effects of…”
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Epidermal Growth Factor Receptor Controls Flat Dysplastic Aberrant Crypt Foci Development and Colon Cancer Progression in the Rat Azoxymethane Model by DOUGHERTY, Urszula, SEHDEV, Amikar, JOSEPH, Loren, HART, John, COHEN, Ezra E. W, ALURI, Lata, FICHERA, Alessandro, BISSONNETTE, Marc, CERDA, Sonia, MUSTAFI, Reba, LITTLE, Nathaniel, WEIHUA YUAN, JAGADEESWARAN, Sujatha, CHUMSANGSRI, Anusara, DELGADO, Jorge, TRETIAKOVA, Maria

“…Purpose: Colonic carcinogenesis deranges growth-regulating epidermal growth factor receptors (EGFR). We previously showed that EGFR signals were up-regulated…”
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Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis by FICHERA, Alessandro, LITTLE, Nathaniel, CAN GONG, TALLERICO, Michael, COHEN, Greg, JOSEPH, Loren, HART, John, TURNER, Jerrold R, BISSONNETTE, Marc, JAGADEESWARAN, Sujatha, DOUGHERTY, Urszula, SEHDEV, Amikar, MUSTAFI, Reba, CERDA, Sonia, WEIHUA YUAN, KHARE, Sharad, TRETIAKOVA, Maria

“…Colonic carcinogenesis involves the progressive dysregulation of homeostatic mechanisms that control growth. The epidermal growth factor (EGF) receptor (EGFR)…”
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Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci by COHEN, Greg, MUSTAFI, Reba, YERIAN, Lisa, TRETIAKOVA, Maria, WEIHUA YUAN, OBARA, Piotr, KHARE, Sharad, SINICROPE, Frank A, FICHERA, Alessandro, BOSS, Gerry R, CARROLL, Robert, BISSONNETTE, Marc, CHUMSANGSRI, Anusara, LITTLE, Nathaniel, NATHANSON, Jeff, CERDA, Sonia, JAGADEESWARAN, Sujatha, DOUGHERTY, Urszula, JOSEPH, Loren, HART, John

“…Aberrant crypt foci (ACF) are collections of abnormal colonic crypts with heterogeneous molecular and pathologic characteristics. Large and dysplastic ACF are…”
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Targeting the Urokinase Plasminogen Activator Receptor Inhibits Ovarian Cancer Metastasis by KENNY, Hilary A, LEONHARDT, Payton, LADANYI, Andras, YAMADA, S. Diane, MONTAG, Anthony, HAE KYUNG IM, JAGADEESWARAN, Sujatha, SHAW, David E, MAZAR, Andrew P, LENGYEL, Ernst

“…To understand the functional and preclinical efficacy of targeting the urokinase plasminogen activator receptor (u-PAR) in ovarian cancer. Expression of u-PAR…”
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Thrombin Induces Tumor Invasion through the Induction and Association of Matrix Metalloproteinase-9 and beta 1-Integrin on the Cell Surface by Radjabi, AReza, Sawada, Kenjiro, Jagadeeswaran, Sujatha, Eichbichler, Alfred, Kenny, Hilary A, Montag, Anthony, Bruno, Katharina, Lengyel, Ernst

“…The procoagulatory serine protease, thrombin, is known to induce invasion and metastasis in various cancers, but the mechanisms by which it promotes…”
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β3 -Integrin Expression on Tumor Cells Inhibits Tumor Progression, Reduces Metastasis, and Is Associated with a Favorable Prognosis in Patients with Ovarian Cancer by Kaur, Swayamjot, Kenny, Hilary A, Jagadeeswaran, Sujatha, Zillhardt, Marion R, Montag, Anthony G, Kistner, Emily, Yamada, S. Diane, Mitra, Anirban K, Lengyel, Ernst

“…The role of the vitronectin receptor (αv β3 -integrin) as a tumor promoter seems well established, and, consequently, therapies that block this integrin are…”
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Abstract 5532: Discovery of A-366, a novel small molecule inhibitor that uncovers an unappreciated role for G9a/GLP in the epigenetics of leukemia by Guo, Jun, Pliushchev, Marina, He, Yupeng, Ferguson, Debra, Jagadeeswaran, Sujatha, Petros, Andrew, Sun, Chaohong, Soni, Niru B., Shaw, Bailin, Korepanova, Alla, Maag, David, Sweis, Ramzi, Buchanan, Fritz G., Michaelides, Michael, Shoemaker, Alex, Tse, Chris, Chiang, Gary G., Pappano, William N.

“…Abstract Understanding the roles of epigenetic alterations in cancer development and maintenance holds great promise for cancer prevention, detection, and…”
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Ursodeoxycholic Acid Suppresses Cox-2 Expression in Colon Cancer: Roles of Ras, p38, and CCAAT/Enhancer-Binding Protein by Khare, S, Mustafi, R, Cerda, S, Yuan, W, Jagadeeswaran, S, Dougherty, U, Tretiakova, M, Samarel, A, Cohen, G, Wang, J

“…In the azoxymethane (AOM) model of experimental rodent colon cancer, cholic acid and its colonic metabolite deoxycholic acid (DCA) strongly promote…”
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{beta}3-Integrin Expression on Tumor Cells Inhibits Tumor Progression, Reduces Metastasis, and Is Associated with a Favorable Prognosis in Patients with Ovarian Cancer by Kaur, Swayamjot, Kenny, Hilary A, Jagadeeswaran, Sujatha, Zillhardt, Marion R, Montag, Anthony G, Kistner, Emily, Yamada, S. Diane, Mitra, Anirban K, Lengyel, Ernst

“…The role of the vitronectin receptor (alpha(v)beta(3)-integrin) as a tumor promoter seems well established, and, consequently, therapies that block this…”
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The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia: e0131716 by Pappano, William N, Guo, Jun, He, Yupeng, Ferguson, Debra, Jagadeeswaran, Sujatha, Osterling, Donald J, Gao, Wenqing, Spence, Julie K, Pliushchev, Marina, Sweis, Ramzi F

“…Histone methyltransferases are epigenetic regulators that modify key lysine and arginine residues on histones and are believed to play an important role in…”
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Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface by Radjabi, A Reza, Sawada, Kenjiro, Jagadeeswaran, Sujatha, Eichbichler, Alfred, Kenny, Hilary A, Montag, Anthony, Bruno, Katharina, Lengyel, Ernst

“…The procoagulatory serine protease, thrombin, is known to induce invasion and metastasis in various cancers, but the mechanisms by which it promotes…”
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Thrombin Induces Tumor Invasion through the Induction and Association of Matrix Metalloproteinase-9 and β1-Integrin on the Cell Surface by A. Reza Radjabi, Kenjiro Sawada, Sujatha Jagadeeswaran, Alfred Eichbichler, Hilary A. Kenny, Anthony Montag, Katharina Bruno, Ernst Lengyel

“…The procoagulatory serine protease, thrombin, is known to induce invasion and metastasis in various cancers, but the mechanisms by which it promotes…”
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β 3-Integrin Expression on Tumor Cells Inhibits Tumor Progression, Reduces Metastasis, and Is Associated with a Favorable Prognosis in Patients with Ovarian Cancer by Kaur, Swayamjot, Kenny, Hilary A., Jagadeeswaran, Sujatha, Zillhardt, Marion R., Montag, Anthony G., Kistner, Emily, Yamada, S. Diane, Mitra, Anirban K., Lengyel, Ernst

“…The role of the vitronectin receptor (α vβ 3-integrin) as a tumor promoter seems well established, and, consequently, therapies that block this integrin are…”
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Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice by Romero, Iris L, Gordon, Ilyssa O, Jagadeeswaran, Sujatha, Mui, Keeley L, Lee, Woo Seok, Dinulescu, Daniela M, Krausz, Thomas N, Kim, Helen H, Gilliam, Melissa L, Lengyel, Ernst

“…Although epidemiologic evidence for the ability of combined oral contraception (OC) to reduce the risk of ovarian cancer (OvCa) is convincing, the biological…”
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S1643 EGFR Controls Flat Dysplastic ACF Development and Colon Cancer Progression in the Rat Azoxymethane Model by Dougherty, Urszula, Sehdev, Amikar, Cerda, Sonia R, Mustafi, Reba, Little, Nathaniel, Yuan, Weihua, Jagadeeswaran, Sujatha, Chumsangsri, Anusara, Delgado, Jorge-Shmuel, Tretiakova, Maria, Joseph, Loren, Hart, John, Cohen, Ezra, Aluri, Lata M, Fichera, Alessandro, Bissonnette, Marc

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