Search Results - "JAECKLE, K."

Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas by van den Bent, MJ, Prof, Wefel, JS, PhD, Schiff, D, MD, Taphoorn, MJB, Prof, Jaeckle, K, MD, Junck, L, MD, Armstrong, T, PhD, Choucair, A, MD, Waldman, AD, PhD, Gorlia, T, MSc, Chamberlain, M, MD, Baumert, BG, MD, Vogelbaum, MA, MD, Macdonald, DR, MD, Reardon, DA, MD, Wen, PY, Prof, Chang, SM, Prof, Jacobs, AH, Prof

“…Summary Although low-grade gliomas (LGG) have a less aggressive course than do high-grade gliomas, the outcome of these tumours is ultimately fatal in most…”
Get full text

Transformation of low grade glioma and correlation with outcome: an NCCTG database analysis by Jaeckle, K. A., Decker, P. A., Ballman, K. V., Flynn, P. J., Giannini, C., Scheithauer, B. W., Jenkins, R. B., Buckner, J. C.

“…Glioblastomas (GBM) may originate de novo (primary), or following transformation from a lower grade glioma (secondary), and it has been postulated that these…”
Get full text

Outcomes and Prognostic Factors in Recurrent Glioma Patients Enrolled Onto Phase II Clinical Trials by WONG, E. T, HESS, K. R, GLEASON, M. J, JAECKLE, K. A, KYRITSIS, A. P, PRADOS, M. D, LEVIN, V. A, YUNG, W. K. A

“…To determine aggregate outcomes and prognostic covariates in patients with recurrent glioma enrolled onto phase II chemotherapy trials. Patients from eight…”
Get full text

A Randomized Controlled Trial Comparing Intrathecal Sustained-release Cytarabine (DepoCyt) to Intrathecal Methotrexate in Patients with Neoplastic Meningitis from Solid Tumors by GLANTZ, M. J, JAECKLE, K. A, HOWELL, S. B, CHAMBERLAIN, M. C, PHUPHANICH, S, RECHT, L, SWINNEN, L. J, MARIA, B, LAFOLLETTE, S, SCHUMANN, G. B, COLE, B. F

“…Standard treatment for neoplastic meningitis requires frequent intrathecal (IT) injections of chemotherapy and is only modestly effective. DepoCyt is a…”
Get full text

Randomized Trial of a Slow-Release Versus a Standard Formulation of Cytarabine for the Intrathecal Treatment of Lymphomatous Meningitis by GLANTZ, M. J, LAFOLLETTE, S, LYTER, D, CHAMBERLAIN, M, MARIA, B. L, SCHIFFER, C, BASHIR, R, THOMAS, D, COWENS, W, HOWELL, S. B, JAECKLE, K. A, SHAPIRO, W, SWINNEN, L, ROZENTAL, J. R, PHUPHANICH, S, ROGERS, L. R, GUTHEIL, J. C, BATCHELOR, T

“…To evaluate the efficacy and safety of a slow-release formulation of cytarabine (DepoCyt; Chiron Corp, Emeryville, CA, and Skye Pharma, Inc, San Diego, CA)…”
Get full text

Phase II Trial of the Antiangiogenic Agent Thalidomide in Patients With Recurrent High-Grade Gliomas by FINE, H. A, FIGG, W. D, YUNG, W. K. A, JAECKLE, K, WEN, P. Y, KYRITSIS, A. P, LOEFFLER, J. S, LEVIN, V. A, BLACK, P. M, KAPLAN, R, PLUDA, J. M

“…Little progress has been made in the treatment of adult high-grade gliomas over the last two decades, thus necessitating a search for novel therapeutic…”
Get full text

Intrathecal treatment of neoplastic meningitis due to breast cancer with a slow-release formulation of cytarabine by JAECKLE, K. A, PHUPHANICH, S, O'DAY, S. J, AKERLEY, W, ALLEN, J, BAIDAS, S, GERTLER, S. Z, GREENBERG, H. S, LAFOLLETTE, S, LESSER, G, MASON, W, RECHT, L, VAN DEN BENT, M. J, WONG, E, CHAMBERLAIN, M. C, COHN, A, GLANTZ, M. J, GUTHEIL, J. C, MARIA, B, MOOTS, P, NEW, P, RUSSELL, C, SHAPIRO, W, AIKEN, R, SWINNEN, L, HOWELL, S. B, BATCHELOR, T, CAMPBELL, T, FULTON, D, GILBERT, M, HEROS, D, ROGERS, L

“…DepoCyte is a slow-release formulation of cytarabine designed for intrathecal administration. The goal of this multi-centre cohort study was to determine the…”
Get full text

Clinical, Molecular, and Molecular-Clinical Profile (MCP) Exploratory Subset Analysis of RTOG 0525: a Phase III Trial Comparing Standard (std) Adjuvant Temozolomide (TMZ) with a Dose-dense (dd) Schedule for Glioblastoma (GBM) by Mehta, M, Wang, M, Aldape, K, Sulman, E, Stupp, R, Jaeckle, K, Blumenthal, D, Erridge, S, Curran, W, Gilbert, M

Get full text

A phase I study of TNP-470 administered to patients with advanced squamous cell cancer of the cervix by KUDELKA, A. P, LEVY, T, JAECKLE, K. A, LOYER, E, STEGER, M, MANTE, R, MAVLIGIT, G, KILLIAN, A, TANG, R. A, GUTTERMAN, J. U, KAVANAGH, J. J, VERSCHRAEGEN, C. F, EDWARDS, C. L, PIAMSOMBOON, S, TERMRUNGRUANGLERT, W, FREEDMAN, R. S, KAPLAN, A. L, KIEBACK, D. G, MEYERS, C. A

“…A Phase I study of the novel angiogenesis inhibitor TNP-470 was performed. Patients with inoperable recurring or metastatic squamous cell cancer of the cervix…”
Get full text

Successful treatment of progressive multifocal leukoencephalopathy with low-dose interleukin-2 by PRZEPIORKA, D, JAECKLE, K. A, BIRDWELL, R. R, FULLER, G. N, KUMAR, A. J, HUH, Y. O, MCCUTCHEON, I

“…A patient with low-grade lymphoma presented 8 months after autologous marrow transplantation with dizziness, aphasia and hemiparesis. Magnetic resonance…”
Get full text

Treating Spinal-Cord Tumors with TTFields — A Simulation Study by Naveh, A., Marciano, T., Bomzon, Z., Divlianska, D., Jaeckle, K.

“…Tumor Treating Fields (TTFields) are an anti-mitotic non-invasive therapy approved for the treatment of certain solid tumors such as glioblastoma (GBM) and…”
Get full text

TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors by Kaba, S E, Kyritsis, A P, Hess, K, Yung, W K, Mercier, R, Dakhil, S, Jaeckle, K A, Levin, V A

“…To evaluate a combination of thioguanine, procarbazine, dibromodulcitol, CCNU (CCNU), fluorouracil, and hydroxyurea (TPDC-FuHu), designed to improve the…”
Get more information

Type IIa ('anti-Hu') antineuronal antibodies produce destruction of rat cerebellar granule neurons in vitro by GREENLEE, J. E, PARKS, T. N, JAECKLE, K. A

“…We reacted dispersed cultures of newborn rat cerebellar granule cells with serum, purified IgG, and CSF from patients with type IIa ("anti-Hu") antibody…”
Get full text

Primary leptomeningeal lymphoma : report of 9 cases, diagnosis with immunocytochemical analysis, and review of the literature by LACHANCE, D. H, O'NEILL, B. P, MACDONALD, D. R, JAECKLE, K. A, WITZIG, T. E, LI, C.-Y, POSNER, J. B

“…We describe 9 patients who presented with a neoplastic meningitis of lymphomatous origin. No evidence of parenchymal central nervous system or systemic tumor…”
Get full text

Guidelines on the detection of paraneoplastic anti-neuronal-specific antibodies : report from the Workshop to the Fourth Meeting of the International Society of Neuro-immunology on paraneoplastic neurological disease, held October 22-23, 1994, in Rotterdam, The Netherlands by MOLL, J. W. B, ANTOINE, J. C, JAECKLE, K. A, TANAKA, K, VECHT, C. J, BRASHEAR, H. R, DELATTRE, J, DRLICEK, M, DROPCHO, E. J, GIOMETTO, B, GRAUS, F, GRENLEE, J, HONNORAT, J

Get full text

A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme by Groves, M D, Maor, M H, Meyers, C, Kyritsis, A P, Jaeckle, K A, Yung, W K, Sawaya, R E, Hess, K, Bruner, J M, Peterson, P, Levin, V A

“…To conduct a Phase II study to evaluate the long-term efficacy and safety of high-dose 5'-bromodeoxyuridine (BrdU) and accelerated radiotherapy followed by…”
Get more information

Immunotherapy of malignant gliomas by Jaeckle, K A

Get more information

A phase II evaluation of tamoxifen in unresectable or refractory meningiomas : a southwest oncology group study by GOODWIN, J. W, CROWLEY, J, HARMON, J. E, STAFFORD, B, JAECKLE, K. A, TOWNSEND, J. J

“…Twenty-one patients with nonresectable refractory meningiomas were registered on a study giving tamoxifen 40 mg per M2 b.i.d. for four days, then 10 mg b.i.d…”
Get full text

Correlation between dynamic MRI and outcome in patients with malignant gliomas by WONG, E. T, JACKSON, E. F, HESS, K. R, SCHOMER, D. F, HAZLE, J. D, KYRITSIS, A. P, JAECKLE, K. A, YUNG, W. K. A, LEVIN, V. A, LEEDS, N. E

“…We assessed the correlation between dynamic MRI results and clinical outcomes in patients with malignant gliomas. Rapid serial MRIs were obtained after bolus…”
Get full text

Pattern of epitopic reactivity of the anti-Hu antibody on HuD with and without paraneoplastic syndrome by Sodeyama, Nobuyuki, Ishida, Kazuyuki, Jaeckle, Kurt A, Zhang, Lixin, Azuma, Arata, Yamada, Masahito, Mizusawa, Hidehiro, Wada, Yoshiaki

“…Previous study has shown that the anti-Hu antibody titre of serum samples from patients with paraneoplastic encephalomyelitis/paraneoplastic sensory…”
Get full text