Search Results - "JAE JOON KOH"

Prevention of autoimmune insulitis by delivery of interleukin-4 plasmid using a soluble and biodegradable polymeric carrier by MINHYUNG LEE, JAE JOON KOH, HAN, Sang-Oh, KYUNG SOO KO, SUNG WAN KIM

“…We delivered interleukin-4 (IL-4) plasmid (pCAGGS-IL-4) using the biodegradable polymer, poly[alpha-(4-aminobutyl)-L-glycolic acid] (PAGA), to prevent…”
Get full text

Water-soluble and low molecular weight chitosan-based plasmid DNA delivery by MINHYUNG LEE, NAH, Jae-Woon, YOUNGMIN KWON, JAE JOON KOH, KYUNG SOO KO, SUNG WAN KIM

“…Chitosan, a natural cationic polysaccharide, is a candidate non-viral vector for gene delivery because of its high positive charges and low cytotoxicity. In…”
Get full text

Controlled release of insulin from injectable biodegradable triblock copolymer by Kim, Y J, Choi, S, Koh, J J, Lee, M, Ko, K S, Kim, S W

Get full text

Synthesis and Characterization of Poly(ethylene glycol)−Insulin Conjugates by Hinds, Ken, Koh, Jae Joon, Joss, Lisa, Liu, Feng, Baudyš, Miroslav, Kim, Sung Wan

“…Human insulin was modified by covalent attachment of short-chain (750 and 2000 Da) methoxypoly (ethylene glycol) (mPEG) to the amino groups of either residue…”
Get full text

Combined Administration of Plasmids Encoding IL-4 and IL-10 Prevents the Development of Autoimmune Diabetes in Nonobese Diabetic Mice by Ko, Kyung Soo, Lee, Minhyung, Koh, Jae Joon, Kim, Sung Wan

“…Studies of animals with spontaneous autoimmune diabetes have revealed that autoreactive T cells that mediate islet β-cell destruction belong to the Th1 subset…”
Get full text

Drug release from nanoparticles of Poly(DL-lactide-co-glycolide) by Nah, Jae-Woon, Jeong, Young-D, Koh, Jae-Joon

Get full text

Systemic administration of TerplexDNA system : Pharmacokinetics and gene expression by Yu, L, Suh, H, Koh, J J, Kim, S W

“…The aim of this study is to extend our previous studies to investigate the TerplexDNA synthetic gene carrier system in pharmacokinetics, biodistribution, and…”
Get full text

미세알부민뇨를 동반한 제2형 당뇨병 환자에서 PAI-1/t-PA 농도 및 PAI-1 4G/5G promoter 다형성에 관한 연구 by 권성희, Seong Hee Kwon, 박영주, Young Joo Park, 정인경, In Kyong Jeong, 고재준, Jae Joon Koh, 박경수, Kyong Soo Park, 김성연, Seong Yeon Kim, 이홍규, Hong Kyu Lee

“…연구배경: 당뇨병 환자에서 죽상경화증의 독립적 인자로 알려진 미세알부민뇨는 일반적인 위험인자인 고혈압, 고지혈증, 비만 등과의 상호작용으로 미세알부민뇨의 당뇨병성 신증에서 죽상경화성 혈관질환의 빈도를 증가시키는 것으로 생각할 수 있으나 이들 위험인자들로 모든 것을 설명할 수는 없다…”
Get full text

Comparison of Glucose Tolerance Categories in the Korean Population According to World Health Organization and American Diabetes Association Diagnostic Criteria by Kyong Soo Park, Chan Soo Shin, Yong Soo Park, Do Joon Park, Jae Joon Koh, Seong Yeon Kim, Hong Kyu Lee

“…Objectives: To compare the prevalence and metabolic profiles of glucose tolerance categories according to World Health Organization(WHO) and 1997 American…”
Get full text

Peripheral blood mitochondrial DNA content is inversely correlated with insulin secretion during hyperglycemic clamp studies in healthy young men by Park, Kyong Soo, Lee, Ki-Up, Song, Ji Hyun, Choi, Cheol Soo, Shin, Chan Soo, Park, Do Joon, Kim, Suk Kyeong, Koh, Jae Joon, Lee, Hong Kyu

“…Abnormalities in mitochondrial DNA(mtDNA) have been implicated in the pathogenesis of diabetes mellitus. We recently reported that decreased mtDNA content…”
Get full text

고유리지방산 혈증이 인슐린 비매개성 포도당 이용과 인슐린 저항성에 미치는 영향에 관한 연구 by 민용기, Yong Ki Min, 안종호, Jong Ho Ahn, 고재준, Jae Joon Koh, 이홍규, Hong Kyu Lee, 민헌기, Hun Ki Min

“…/A Background: In vivo glucose uptake occurs via two mechanisms, namely insulin-mediated glucose uptake(IMGU) and non-insulin-mediated glucose up- take(NIMGU)…”
Get full text

Peripheral blood mitochondrial DNA content correlates with lipid oxidation rate during euglycemic clamps in healthy young men by Park, Kyong Soo, Song, Ji Hyun, Lee, Ki-Up, Choi, Cheol Soo, Koh, Jae Joon, Shin, Chan Soo, Lee, Hong Kyu

“…Both qualitative and quantitative changes in mitochondrial DNA (mtDNA) have been implicated in the pathogenesis of diabetes mellitus. It was previously found…”
Get full text

인슐린비의존형 당뇨병 발현 이전에 말초혈액 백혈구의 미토콘드리아 DNA 양의 감소에 관한 연구 by 고재준, Jae Joon Koh, 안종호, Jong Ho Ahn, 권순자, Soon Ja Kwon, 송지현, Ji Hyun Song, 신찬수, Chan Soo Shin, 박도준, Do Joon park, 박경수, Kyong Soo Park, 김성연, Seong yeon Kim, 이홍규, Hong Kyu Lee

“…/A Background: Mitochondrial mutations and deletions, have been implicated in the pathogenesis of diabetes mellitus. This can explain only a very small…”
Get full text

당뇨병 환자 단핵구의 Manganese Superoxide Dismutase ( Mn - SOD ) 활성도에 관한 연구 by 고재준, Jae Joon Koh, 심찬수, Chan Soo Shin, 오태근, Tae Gun Oh, 전재석, Jae Seok Jeon, 박경수, Kyong Soo park, 김성연, Seong Yeon Kim, 조보연, Bo Youn Cho, 이홍규, Hong Kyu Lee, 고창순, Chang Soon Koh, 민헌기, Hun Ki Min, 고경수, Kyung Soo Ko

“…/A Background: Free radical injury is one of the environmental factors related to the development of diabetes mellitus. Oxidative injury may also have a role…”
Get full text

당뇨병에 병발한 고지혈증에 대한 Acipimox의 효과 by 김현규, Hyeon Kyu Kim, 고재준, Jae Joon Koh, 박용수, Yong Soo Park, 박경수, Kyong Soo Park, 김성연, Seong Yeon Kim, 조보연, Bo Youn Cho, 이홍규, Hong Kyu Lee, 고창순, Chang Soon Koh, 민헌기, Hun Ki Min

“…/A Background: Hyperlipidemia is commonly associated with non-insulin dependent diabetes mellitus (NIDDM) and acts as a predisposing factor to the development…”
Get full text

당뇨병 환자에서 당화인슐린의 생체내 활성 by 박중열, 고재준, 박경수, 이문규, 김성연, 조보연, 이홍규, 고창순, 민헌기, 김성환, Joong Yeol Park, Jae Joon Koh, Kyong Soo Park, Moon Kyu Lee, Seong Yeon Kim, Bo Youn Cho, Hong Kyu Lee, Chang Soon Koh, Hun Ki Min, Sung Wan Kim

“…/A /A…”
Get full text

Polymorphism in the promoter and exon 1 of the cytotoxic T lymphocyte antigen-4 gene associated with autoimmune thyroid disease in Koreans by Park, Y J, Chung, H K, Park, D J, Kim, W B, Kim, S W, Koh, J J, Cho, B Y

“…The objective of this study was to examine the polymorphism in the cytotoxic T lymphocyte antigen-4 (CTLA-4) gene and its relationship with autoimmune thyroid…”
Get more information

The effect of zinc-crystallized glucagon-like peptide-1 on insulin secretion of macroencapsulated pancreatic islets by Gappa, H, Baudys, M, Koh, J J, Kim, S W, Bae, Y H

“…This research investigates the use of an insulinotropic factor, glucagon-like peptide-1 (GLP-1), to enhance insulin secretion from islets within a…”
Get more information

Repression of GAD Autoantigen Expression in Pancreas β-Cells by Delivery of Antisense Plasmid/PEG-g-PLL Complex by Lee, Minhyung, Han, Sang-oh, Ko, Kyung Soo, Koh, Jae Joon, Park, Jong-Sang, Yoon, Ji-Won, Kim, Sung Wan

“…It was previously reported that silencing of the expression of glutamic acid decarboxylase (GAD) in transgenic nonobese diabetic (NOD) mice completely…”
Get full text

Repression of GAD Autoantigen Expression in Pancreas [beta]-Cells by Delivery of Antisense Plasmid/PEG-g-PLL Complex by Lee, Minhyung, Han, Sang-oh, Ko, Kyung Soo, Koh, Jae Joon, Park, Jong-sang, Yoon, Ji-won, Kim, Sung Wan

“…It was previously reported that silencing of the expression of glutamic acid decarboxylase (GAD) in transgenic nonobese diabetic (NOD) mice completely…”
Get full text