Search Results - "JACOBS, R"

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis by Harbut, Michael B., Vilchèze, Catherine, Luo, Xiaozhou, Hensler, Mary E., Guo, Hui, Yang, Baiyuan, Chatterjee, Arnab K., Nizet, Victor, Jacobs, William R., Schultz, Peter G., Wang, Feng

“…Infections caused by antibiotic-resistant bacteria are a rising public health threat and make the identification of new antibiotics a priority. From a…”
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Breakfast Frequency and Development of Metabolic Risk by ODEGAARD, Andrew O, JACOBS, David R, STEFFEN, Lyn M, VAN HORN, Linda, LUDWIG, David S, PEREIRA, Mark A

“…The relation of breakfast intake frequency to metabolic health is not well studied. The aim of this study was to examine breakfast intake frequency with…”
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Diet Soda Intake and Risk of Incident Metabolic Syndrome and Type 2 Diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA) by Nettleton, Jennifer A, Lutsey, Pamela L, Wang, Youfa, Lima, João A, Michos, Erin D, Jacobs, David R. Jr

“…OBJECTIVE: We determined associations between diet soda consumption and risk of incident metabolic syndrome, its components, and type 2 diabetes in the…”
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Primary cilia: Cell and molecular mechanosensors directing whole tissue function by Spasic, Milos, Jacobs, Christopher R.

“…Primary cilia are immotile, microtubule-based organelles extending from the surface of nearly every mammalian cell. Mechanical stimulation causes deflection of…”
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Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction by Vilchèze, Catherine, Hartman, Travis, Weinrick, Brian, Jacobs, William R.

“…Drugs that kill tuberculosis more quickly could shorten chemotherapy significantly. In Escherichia coli , a common mechanism of cell death by bactericidal…”
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Food synergy: an operational concept for understanding nutrition by Jacobs, David R. Jr, Gross, Myron D, Tapsell, Linda C

“…Research and practice in nutrition relate to food and its constituents, often as supplements. In food, however, the biological constituents are coordinated. We…”
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A world without tuberculosis: moving from imagination to reality by Jacobs, William R.

“…Tuberculosis (TB), caused by Mycobacterium tuberculosis infection, remains a leading cause of death from an infectious agent, resulting in more than a million…”
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Role for Mycobacterium tuberculosis Membrane Vesicles in Iron Acquisition by Prados-Rosales, Rafael, Weinrick, Brian C, Piqué, Daniel G, Jacobs, William R, Casadevall, Arturo, Rodriguez, G. Marcela

“…Mycobacterium tuberculosis releases membrane vesicles packed with molecules that can modulate the immune response. Because environmental conditions often…”
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obligately aerobic soil bacterium activates fermentative hydrogen production to survive reductive stress during hypoxia by Berney, Michael, Greening, Chris, Conrad, Ralf, Jacob, William R., Cook, Gregory M.

“…Oxygen availability is a major factor and evolutionary force determining the metabolic strategy of bacteria colonizing an environmental niche. In the soil,…”
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Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes by Lee, Duk-Hee, Steffes, Michael W, Sjödin, Andreas, Jones, Richard S, Needham, Larry L, Jacobs, Jr, David R

“…There is emerging evidence that background exposure to persistent organic pollutants (POPs) are important in the development of conditions predisposing to…”
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NLRs, inflammasomes, and viral infection by Jacobs, Sarah R., Damania, Blossom

“…Review on the interplay between NLR proteins, and RNA and DNA viruses. NLR proteins are innate immune sensors that respond to microbial infection. Upon…”
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Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application by Kerantzas, Christopher A, Jacobs, Jr, William R

“…Tuberculosis is a global health problem that causes the death of approximately 1.5 million people worldwide each year (WHO, p. 1-126, , 2015). Treatment of…”
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CBCT-based bone quality assessment: are Hounsfield units applicable? by Pauwels, R, Jacobs, R, Singer, S R, Mupparapu, M

“…CBCT is a widely applied imaging modality in dentistry. It enables the visualization of high-contrast structures of the oral region (bone, teeth, air cavities)…”
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Lengthening primary cilia enhances cellular mechanosensitivity by Spasic, M, Jacobs, C R

“…The primary cilium is a mechanosensor in a variety of mammalian cell types, initiating and directing intracellular signalling cascades in response to external…”
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Accuracy of computer-aided implant placement by Van Assche, N., Vercruyssen, M., Coucke, W., Teughels, W., Jacobs, R., Quirynen, M.

“…Aim To assess the accuracy of static computer‐guided implant placement. Material and methods Electronic and manual literature searches were conducted to…”
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Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses by Vandenberg, Laura N, Colborn, Theo, Hayes, Tyrone B, Heindel, Jerrold J, Jacobs, David R, Lee, Duk-Hee, Shioda, Toshi, Soto, Ana M, vom Saal, Frederick S, Welshons, Wade V, Zoeller, R. Thomas, Myers, John Peterson

“…For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional concepts in toxicology, in particular the dogma of “the dose makes…”
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The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions by Koleske, Benjamin N, Jacobs, Jr, William R, Bishai, William R

“…First achieved in 1998 by Cole et al., the complete genome sequence of Mycobacterium tuberculosis continues to provide an invaluable resource to understand…”
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Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV by Goldberg, Daniel E., Siliciano, Robert F., Jacobs, William R.

“…Although caused by vastly different pathogens, the world's three most serious infectious diseases, tuberculosis, malaria, and HIV-1 infection, share the common…”
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Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year Prospective Study in CARDIA (Coronary Artery Risk Development in Young Adults) by GUNDERSON, Erica P, JACOBS, David R, CHIANG, Vicky, LEWIS, Cora E, JUANRAN FENG, QUESENBERRY, Charles P, SIDNEY, Stephen

“…Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year…”
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Magnesium Intake in Relation to Systemic Inflammation, Insulin Resistance, and the Incidence of Diabetes by Kim, Dae Jung, Xun, Pengcheng, Liu, Kiang, Loria, Catherine, Yokota, Kuninobu, Jacobs, David R. Jr, He, Ka

“…OBJECTIVE: To investigate the long-term associations of magnesium intake with incidence of diabetes, systemic inflammation, and insulin resistance among young…”
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