Search Results - "JACOBELLI, J"

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  1. 1

    Immune cell trafficking to the islets during type 1 diabetes by Sandor, A. M., Jacobelli, J., Friedman, R. S.

    Published in Clinical and experimental immunology (01-12-2019)
    “…Summary Inhibition of immune cell trafficking to the pancreatic islets during type 1 diabetes (T1D) has therapeutic potential, since targeting of T cell and B…”
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    Journal Article
  2. 2

    Cutting Edge: Functional Role for Proline-Rich Tyrosine Kinase 2 in NK Cell-Mediated Natural Cytotoxicity by Gismondi, Angela, Jacobelli, Jordan, Mainiero, Fabrizio, Paolini, Rossella, Piccoli, Mario, Frati, Luigi, Santoni, Angela

    Published in The Journal of immunology (1950) (01-03-2000)
    “…Protein tyrosine kinase activation is one of the first biochemical events in the signaling pathway leading to activation of NK cell cytolytic machinery. Here…”
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    Journal Article
  3. 3

    Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder by MILELLA, M, JACOBELLI, J, CAVALLO, F, GUARINI, A, VELOTTI, F, FRATI, L, FOA, R, FORNI, G, SANTONI, A

    Published in British journal of cancer (01-02-1999)
    “…Transitional cell carcinoma of the bladder is one of the human cancers most responsive to immunotherapy, and local interleukin-2 (IL-2) production appears to…”
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    Journal Article
  4. 4
  5. 5

    A single class II myosin modulates T cell motility and stopping, but not synapse formation by Krummel, Matthew F, Jacobelli, Jordan, Chmura, Stephen A, Buxton, Denis B, Davis, Mark M

    Published in Nature immunology (01-05-2004)
    “…Upon encountering an antigen, motile T cells stop crawling, change morphology and ultimately form an 'immunological synapse'. Although myosin motors are…”
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    Journal Article
  6. 6

    Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect by Gismondi, Angela, Cifaldi, Loredana, Mazza, Cinzia, Giliani, Silvia, Parolini, Silvia, Morrone, Stefania, Jacobelli, Jordan, Bandiera, Elisabetta, Notarangelo, Luigi, Santoni, Angela

    Published in Blood (15-07-2004)
    “…In this study we show that Wiskott-Aldrich syndrome protein (WASp), a critical regulator of actin cytoskeleton that belongs to the Scar/WAVE family, plays a…”
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    Journal Article
  7. 7

    RAC1/P38 MAPK Signaling Pathway Controls beta 1 Integrin-Induced Interleukin-8 Production in Human Natural Killer Cells by Mainiero, F, Soriani, A, Strippoli, R, Jacobelli, J, Gismondi, A, Piccoli, M, Frati, L, Santoni, A

    Published in Immunity (Cambridge, Mass.) (01-01-2000)
    “…The MAP kinase (MAPK) p38 plays a key role in regulating inflammatory responses. Here, we demonstrate that beta 1 integrin ligation on human NK cells results…”
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    Journal Article
  8. 8

    New views of the immunological synapse: variations in assembly and function by Jacobelli, Jordan, Andres, Pietro G, Boisvert, Judie, Krummel, Matthew F

    Published in Current opinion in immunology (01-06-2004)
    “…The interaction of T cells with antigen-presenting cells results in the formation of a contact face, termed the immunological synapse. The prototypical…”
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    Journal Article
  9. 9

    Proline-Rich Tyrosine Kinase 2 and Rac Activation by Chemokine and Integrin Receptors Controls NK Cell Transendothelial Migration by Gismondi, Angela, Jacobelli, Jordan, Strippoli, Raffaele, Mainiero, Fabrizio, Soriani, Alessandra, Cifaldi, Loredana, Piccoli, Mario, Frati, Luigi, Santoni, Angela

    Published in The Journal of immunology (1950) (15-03-2003)
    “…Protein tyrosine kinase activation is an important requisite for leukocyte migration. Herein we demonstrate that NK cell binding to endothelium activates…”
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    Journal Article
  10. 10

    Mechanisms of T cell motility and arrest: Deciphering the relationship between intra- and extracellular determinants by Friedman, Rachel S., Jacobelli, Jordan, Krummel, Matthew F.

    Published in Seminars in Immunology (01-12-2005)
    “…T lymphocytes are capable of rapid motility in vitro and in vivo. Upon antigen recognition, they may stop crawling and form a stable cell–cell contact called…”
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    Journal Article
  11. 11

    Integrin-mediated ras-extracellular regulated kinase (ERK) signaling regulates interferon gamma production in human natural killer cells by Mainiero, F, Gismondi, A, Soriani, A, Cippitelli, M, Palmieri, G, Jacobelli, J, Piccoli, M, Frati, L, Santoni, A

    Published in The Journal of experimental medicine (05-10-1998)
    “…Recent evidence indicates that integrin engagement results in the activation of biochemical signaling events important for regulating different cell functions,…”
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    Journal Article
  12. 12

    T cell synapse assembly: proteins, motors and the underlying cell biology by Tooley, Aaron J., Jacobelli, Jordan, Moldovan, Maria-Cristina, Douglas, Adam, Krummel, Matthew F.

    Published in Seminars in immunology (01-02-2005)
    “…A tantalizing feature of the ‘immunological synapse’ is the segregation of transmembrane proteins into activating clusters and their underlying signalosomes…”
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    Journal Article
  13. 13
  14. 14

    Functional Role for Proline-Rich Tyrosine Kinase 2 in NK Cell-Mediated Natural Cytotoxicity by Gismondi, A, Jacobelli, J, Mainiero, F, Paolini, R, Piccoli, M, Frati, L, Santoni, A

    Published in The Journal of immunology (1950) (01-03-2000)
    “…Protein tyrosine kinase activation is one of the first biochemical events in the signaling pathway leading to activation of NK cell cytolytic machinery. Here…”
    Get full text
    Journal Article
  15. 15

    RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells by Mainiero, F, Soriani, A, Strippoli, R, Jacobelli, J, Gismondi, A, Piccoli, M, Frati, L, Santoni, A

    Published in Immunity (Cambridge, Mass.) (01-01-2000)
    “…The MAP kinase (MAPK) p38 plays a key role in regulating inflammatory responses. Here, we demonstrate that beta1 integrin ligation on human NK cells results in…”
    Get full text
    Journal Article
  16. 16