Search Results - "JACKSON, Annette M"

Cell-free DNA diagnostics in transplantation utilizing next generation sequencing by Jackson, Annette M., Amato-Menker, Carly, Bettinotti, Maria

“…The use of Next Generation Sequencing (NGS) to interrogate cell-free DNA (cfDNA) as a transplant diagnostic provides a crucial step in improving the accuracy…”
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A closer look at rituximab induction on HLA antibody rebound following HLA-incompatible kidney transplantation by Jackson, Annette M, Kraus, Edward S, Orandi, Babak J, Segev, Dorry L, Montgomery, Robert A, Zachary, Andrea A

“…Rituximab has been used to increase the efficacy of desensitization protocols for human leukocyte antigen (HLA)-incompatible kidney transplantation; however,…”
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Transcriptional responses define dysregulated immune activation in Hepatitis C (HCV)-naïve recipients of HCV-infected donor kidneys by Steinbrink, Julie M, Miller, Cameron, Myers, Rachel A, Sanoff, Scott, Mazur, Anna, Burke, Thomas W, Byrns, Jennifer, Jackson, Annette M, Luo, Xunrong, McClain, Micah T

“…Renal transplantation from hepatitis C (HCV) nucleic acid amplification test-positive (NAAT-positive) donors to uninfected recipients has greatly increased the…”
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Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant by Pineda, Silvia, Sigdel, Tara K, Chen, Jieming, Jackson, Annette M, Sirota, Marina, Sarwal, Minnie M

“…Transplant rejection is the critical clinical end-point limiting indefinite survival after histocompatibility antigen (HLA) mismatched organ transplantation…”
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Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells by Song, Shengli, Manook, Miriam, Kwun, Jean, Jackson, Annette M, Knechtle, Stuart J, Kelsoe, Garnett

“…Antibody-mediated allograft rejection (AMR) causes more kidney transplant failure than any other single cause. AMR is mediated by antibodies recognizing…”
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Editorial: Sensitization and Desensitization in Organ Transplantation by Anwar, Imran J, Jackson, Annette M, Locke, Jayme E, Kwun, Jean

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Harnessing the B Cell Response in Kidney Transplantation - Current State and Future Directions by Anwar, Imran J, DeLaura, Isabel F, Gao, Qimeng, Ladowski, Joseph, Jackson, Annette M, Kwun, Jean, Knechtle, Stuart J

“…Despite dramatic improvement in kidney transplantation outcomes over the last decades due to advent of modern immunosuppressive agents, long-term outcomes…”
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A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines by Song, Shengli, Manook, Miriam, Kwun, Jean, Jackson, Annette M., Knechtle, Stuart J., Kelsoe, Garnett

“…Multiplex immunoassays with acellular antigens are well-established based on solid-phase platforms such as the Luminex ® technology. Cell barcoding by…”
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Genetic risk variants for childhood nephrotic syndrome and corticosteroid response by Cason, Rachel K, Chambers, Eileen, Tu, Tiffany, Chryst-Stangl, Megan, Huggins, Kinsie, Lane, Brandon M, Ochoa, Alejandro, Jackson, Annette M, Gbadegesin, Rasheed A

“…The etiology of most cases of nephrotic syndrome (NS) remains unknown, therefore patients are phenotypically categorized based on response to corticosteroid…”
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Impact of pronase on flow cytometric crossmatch outcome by Hetrick, Sarah J, Schillinger, Karl P, Zachary, Andrea A, Jackson, Annette M

“…Abstract Pronase treatment of lymphocytes is used to reduce nonspecific binding of immunoglobulins in flow cytometric crossmatch (FCXM) tests and at higher…”
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Corrigendum: Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant by Pineda, Silvia, Sigdel, Tara K, Chen, Jieming, Jackson, Annette M, Sirota, Marina, Sarwal, Minnie M

“…[This corrects the article on p. 1687 in vol. 8, PMID: 29259604.]…”
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Correction: Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis by Bouquegneau, Antoine, Loheac, Charlotte, Aubert, Olivier, Bouatou, Yassine, Viglietti, Denis, Empana, Jean-Philippe, Ulloa, Camilo, Murad, Mohammad Hassan, Legendre, Christophe, Glotz, Denis, Jackson, Annette M, Zeevi, Adriana, Schaub, Stephan, Taupin, Jean-Luc, Reed, Elaine F, Friedewald, John J, Tyan, Dolly B, Süsal, Caner, Shapiro, Ron, Woodle, E Steve, Hidalgo, Luis G, O'Leary, Jacqueline, Montgomery, Robert A, Kobashigawa, Jon, Jouven, Xavier, Jabre, Patricia, Lefaucheur, Carmen, Loupy, Alexandre

“…[This corrects the article DOI: 10.1371/journal.pmed.1002572.]…”
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HLA Loci and Recurrence of Focal Segmental Glomerulosclerosis in Pediatric Kidney Transplantation by Shaw, Brian I., Ochoa, Alejandro, Chan, Cliburn, Nobuhara, Chloe, Gbadegesin, Rasheed, Jackson, Annette M., Chambers, Eileen T.

“…Recurrent focal segmental glomerulosclerosis (FSGS) after kidney transplantation accounts for the majority of allograft failures in children with primary FSGS…”
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The problem of transplanting the sensitized patient: whose problem is it? by Jackson, Annette M, Zachary, Andrea A

“…Transplantation is the treatment of choice for end-stage renal failure and a life-saving treatment for failure of other major organs. Improvements in surgical…”
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Rejection in the setting of non‐HLA antibody: New tools for navigating bench to bedside by Jackson, Annette M., Glass, Carolyn

“…The authors explore new laboratory tools to interrogate the role of non‐HLA antibodies in acute rejection following heart transplantation. Butler et al's…”
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Diagnostic Potential of Minimally Invasive Biomarkers: A Biopsy-centered Viewpoint From the Banff Minimally Invasive Diagnostics Working Group by Huang, Edmund, Mengel, Michael, Clahsen-van Groningen, Marian C., Jackson, Annette M.

“…With recent advances and commercial implementation of minimally invasive biomarkers in kidney transplantation, new strategies for the surveillance of allograft…”
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Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study by Loupy, Alexandre, Aubert, Olivier, Orandi, Babak J, Naesens, Maarten, Bouatou, Yassine, Raynaud, Marc, Divard, Gillian, Jackson, Annette M, Viglietti, Denis, Giral, Magali, Kamar, Nassim, Thaunat, Olivier, Morelon, Emmanuel, Delahousse, Michel, Kuypers, Dirk, Hertig, Alexandre, Rondeau, Eric, Bailly, Elodie, Eskandary, Farsad, Böhmig, Georg, Gupta, Gaurav, Glotz, Denis, Legendre, Christophe, Montgomery, Robert A, Stegall, Mark D, Empana, Jean-Philippe, Jouven, Xavier, Segev, Dorry L, Lefaucheur, Carmen

“…AbstractObjectiveTo develop and validate an integrative system to predict long term kidney allograft failure.DesignInternational cohort study.SettingThree…”
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Tracking HLA Antibody Changes among Kidney Waitlist Candidates: One Protocol May Not Fit All by Jackson, Annette M, Manook, Miriam

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Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report by Tambur, Anat R., Campbell, Patricia, Claas, Frans H., Feng, Sandy, Gebel, Howard M., Jackson, Annette M., Mannon, Roslyn B., Reed, Elaine F., Tinckam, Kathryn, Askar, Medhat, Chandraker, Anil, Chang, Patricia P., Colvin, Monica, Demetris, Anthony‐Jake, Diamond, Joshua M., Dipchand, Anne I., Fairchild, Robert L., Ford, Mandy L., Friedewald, John, Gill, Ronald G., Glotz, Denis, Goldberg, Hilary, Hachem, Ramsey, Knechtle, Stuart, Kobashigawa, Jon, Levine, Deborah J., Levitsky, Joshua, Mengel, Michael, Milford, Edgar, Newell, Kenneth A., O’Leary, Jacqueline G., Palmer, Scott, Randhawa, Parmjeet, Smith, John, Snyder, Laurie, Starling, Randall C., Sweet, Stuart, Taner, Timucin, Taylor, Craig J., Woodle, Steve, Zeevi, Adriana, Nickerson, Peter

“…The presence of preexisting (memory) or de novo donor‐specific HLA antibodies (DSAs) is a known barrier to successful long‐term organ transplantation. Yet,…”
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Understanding the impact of HLA molecular mismatch in solid organ transplantation: Are we there yet? by Jackson, Annette M., Pinelli, David F.

“…Although quantification of HLA molecular mismatch holds significant potential to assess risk for allograft rejection, effective clinical implementation…”
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