Search Results - "JACKSON, Alicia R"

Heterogeneity of dynamic shear properties of the meniscus: A comparison between tissue core and surface layers by Schwartz, Gabi, Morejon, Andy, Gracia, Julissa, Best, Thomas M., Jackson, Alicia R., Travascio, Francesco

“…Damage to the meniscus has been associated with excessive shear loads. Aimed at elucidating meniscus pathophysiology, previous studies have investigated the…”
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Biomechanical properties of porcine meniscus as determined via AFM: Effect of region, compartment and anisotropy by Orton, Kevin, Batchelor, Wyndham, Ziebarth, Noel M, Best, Thomas M, Travascio, Francesco, Jackson, Alicia R

“…The meniscus is a fibrocartilaginous tissue that plays an essential role in load transmission, lubrication, and stabilization of the knee. Loss of meniscus…”
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Assessing the role of surface layer and molecular probe size in diffusion within meniscus tissue by Schwartz, Gabi, Best, Thomas M, Chen, Cheng-Bang, Travascio, Francesco, Jackson, Alicia R

“…Diffusion within extracellular matrix is essential to deliver nutrients and larger metabolites to the avascular region of the meniscus. It is well known that…”
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Hydraulic permeability of meniscus fibrocartilage measured via direct permeation: Effects of tissue anisotropy, water volume content, and compressive strain by Kleinhans, Kelsey L., Jackson, Alicia R.

“…Hydraulic permeability is an important material property of cartilaginous tissues, governing the rate of fluid flow, which is crucial to tissue biomechanics…”
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Computational Modeling Intervertebral Disc Pathophysiology: A Review by Volz, Mallory, Elmasry, Shady, Jackson, Alicia R, Travascio, Francesco

“…Lower back pain is a medical condition of epidemic proportion, and the degeneration of the intervertebral disc has been identified as a major contributor. The…”
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Development of Improved Confined Compression Testing Setups for Use in Stress Relaxation Testing of Viscoelastic Biomaterials by El Kommos, Anthony, Jackson, Alicia R, Andreopoulos, Fotios, Travascio, Francesco

“…The development of cell-based biomaterial alternatives holds significant promise in tissue engineering applications, but it requires accurate mechanical…”
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Compressive Properties and Hydraulic Permeability of Human Meniscus: Relationships With Tissue Structure and Composition by Morejon, Andy, Norberg, Christopher D, De Rosa, Massimiliano, Best, Thomas M, Jackson, Alicia R, Travascio, Francesco

“…The meniscus is crucial in maintaining knee function and protecting the joint from secondary pathologies, including osteoarthritis. The meniscus has been shown…”
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Electrical conductivity and ion diffusion in porcine meniscus: effects of strain, anisotropy, and tissue region by Kleinhans, Kelsey L, McMahan, Jeffrey B, Jackson, Alicia R

“…Abstract The purpose of the present study was to investigate the effects of mechanical strain, anisotropy, and tissue region on electrical conductivity and ion…”
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Effects of solute size and tissue composition on molecular and macromolecular diffusivity in human knee cartilage by Travascio, Francesco, Valladares-Prieto, Sabrina, Jackson, Alicia R.

“…Articular cartilage is an avascular tissue. Accordingly, diffusivity represents a fundamental transport mechanism for nutrients and other molecular signals…”
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Tensile energy dissipation and mechanical properties of the knee meniscus: relationship with fiber orientation, tissue layer, and water content by Morejon, Andy, Dalbo, Pedro L, Best, Thomas M, Jackson, Alicia R, Travascio, Francesco

“…The knee meniscus distributes and dampens mechanical loads. It is composed of water (∼70%) and a porous fibrous matrix (∼30%) with a central core that is…”
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Effect of molecular weight and tissue layer on solute partitioning in the knee meniscus by Morejon, Andy, Schwartz, Gabi, Best, Thomas M., Travascio, Francesco, Jackson, Alicia R.

“…Knee meniscus tissue is partly vascularized, meaning that nutrients must be transported through the extracellular matrix of the avascular portion to reach…”
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Effects of Oxygen Concentration and Culture Time on Porcine Nucleus Pulposus Cell Metabolism: An in vitro Study by Jaworski, Lukas M, Kleinhans, Kelsey L, Jackson, Alicia R

“…Low back pain is a common ailment that affects millions of individuals each year and is linked to degeneration of the intervertebral discs in the spine…”
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Relationship between solute transport properties and tissue morphology in human annulus fibrosus by Travascio, Francesco, Jackson, Alicia R., Brown, Mark D., Gu, Wei Yong

“…Poor nutritional supply to the intervertebral disc is believed to be an important factor leading to disc degeneration. However, little is known regarding…”
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Effect of Compression and Anisotropy on the Diffusion of Glucose in Annulus Fibrosus by JACKSON, Alicia R, YUAN, Tai-Yi, HUANG, Chun-Yuh C, TRAVASCIO, Francesco, WEI YONG GU

“…Investigation of the effect of static compression and anisotropy on the apparent diffusivity of glucose in bovine annulus fibrosus (AF). OBJECTIVE. To…”
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The nutrition of the human meniscus: A computational analysis investigating the effect of vascular recession on tissue homeostasis by Travascio, Francesco, Jackson, Alicia R.

“…The meniscus is essential to the functioning of the knee, offering load support, congruency, lubrication, and protection to the underlying cartilage. Meniscus…”
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Viscoelastic and equilibrium shear properties of human meniscus: Relationships with tissue structure and composition by Norberg, Christopher, Filippone, Giovanni, Andreopoulos, Fotios, Best, Thomas M., Baraga, Michael, Jackson, Alicia R., Travascio, Francesco

“…The meniscus is crucial in maintaining the knee function and protecting the joint from secondary pathologies, including osteoarthritis. Although most of the…”
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Human mesenchymal stem/stromal cell-derived extracellular vesicle transport in meniscus fibrocartilage by Schwartz, Gabi, Rana, Samir, Jackson, Alicia R, Leñero, Clarissa, Best, Thomas M, Kouroupis, Dimitrios, Travascio, Francesco

“…Extracellular vesicles (EVs) derived from endometrial-derived mesenchymal stem/stromal cells (eMSC) play a crucial role in tissue repair due to their…”
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Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach by De Rosa, Massimiliano, Filippone, Giovanni, Best, Thomas M., Jackson, Alicia R., Travascio, Francesco

“…The extracellular matrix (ECM) of the meniscus is a gel-like water solution of proteoglycans embedding bundles of collagen fibers mainly oriented…”
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Cell viability in intervertebral disc under various nutritional and dynamic loading conditions: 3d Finite element analysis by Zhu, Qiaoqiao, Jackson, Alicia R, Gu, Wei Yong

“…Abstract In this study, a new cell density model was developed and incorporated into the formulation of the mechano-electrochemical mixture theory to…”
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Association Between Intervertebral Disc Degeneration and Cigarette Smoking: Clinical and Experimental Findings by Jackson, Alicia R., PhD, Dhawale, Arjun A., MD, Brown, Mark D., MD, PhD

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