Search Results - "J. Segal"

Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students: A Systematic Review and Meta-Analysis by Rotenstein, Lisa S, Ramos, Marco A, Torre, Matthew, Segal, J. Bradley, Peluso, Michael J, Guille, Constance, Sen, Srijan, Mata, Douglas A

“…IMPORTANCE: Medical students are at high risk for depression and suicidal ideation. However, the prevalence estimates of these disorders vary between studies…”
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What "First, Do No Harm" Means in Pediatrics by Segal, J Bradley

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COVID-19 and Kawasaki Disease: Novel Virus and Novel Case by Jones, Veena G, Mills, Marcos, Suarez, Dominique, Hogan, Catherine A, Yeh, Debra, Segal, J Bradley, Nguyen, Elizabeth L, Barsh, Gabrielle R, Maskatia, Shiraz, Mathew, Roshni

“…In the midst of the coronavirus disease 2019 (COVID-19) pandemic, we are seeing widespread disease burden affecting patients of all ages across the globe…”
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Extramammary Paget's disease: a review of the literature by Simonds, Robert M., Segal, Robert J., Sharma, Amit

“…Extramammary Paget's disease (EMPD) is a rare cutaneous malignancy. The disease typically affects older individuals aged 60–80 years and is seen most…”
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Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing by O’Geen, Henriette, Tomkova, Marketa, Combs, Jacquelyn A, Tilley, Emma K, Segal, David J

“…Abstract Precision epigenome editing has gained significant attention as a method to modulate gene expression without altering genetic information. However, a…”
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Bilateral Marcus Gunn jaw-Winking Syndrome in a Neonate with Congenital Neurosyphilis by Johnson, Alexandra, Silverman, Andrew, Segal, J. Bradley, Beres, Shannon

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Genome Engineering at the Dawn of the Golden Age by Segal, David J, Meckler, Joshua F

“…Genome engineering-the ability to precisely alter the DNA information in living cells-is beginning to transform human genetics and genomics. Advances in tools…”
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What childhood obesity prevention programmes work? A systematic review and meta‐analysis by Wang, Y, Cai, L, Wu, Y, Wilson, R. F, Weston, C, Fawole, O, Bleich, S. N, Cheskin, L. J, Showell, N. N, Lau, B. D, Chiu, D. T, Zhang, A, Segal, J

“…Previous reviews of childhood obesity prevention have focused largely on schools and findings have been inconsistent. Funded by the US Agency for Healthcare…”
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American College of Sports Medicine Roundtable on Exercise Guidelines for Cancer Survivors by SCHMITZ, Kathryn H, COURNEYA, Kerry S, SCHNEIDER, Carole M, VON GRUENIGEN, Vivian E, SCHWARTZ, Anna L, MATTHEWS, Charles, DEMARK-WAHNEFRIED, Wendy, GALVAO, Daniel A, PINTO, Bernardine M, IRWIN, Melinda L, WOLIN, Kathleen Y, SEGAL, Roanne J, LUCIA, Alejandro

“…Early detection and improved treatments for cancer have resulted in roughly 12 million survivors alive in the United States today. This growing population…”
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Effects of Exercise during Adjuvant Chemotherapy on Breast Cancer Outcomes by COURNEYA, KERRY S, SEGAL, ROANNE J, MCKENZIE, DONALD C, DONG, HUIRU, GELMON, KAREN, FRIEDENREICH, CHRISTINE M, YASUI, YUTAKA, REID, ROBERT D, CRAWFORD, JENNIFER J, MACKEY, JOHN R

“…Observational studies suggest that physical activity after a breast cancer diagnosis is associated with improved cancer outcomes; however, no randomized data…”
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SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation by Johnson, Lianna M., Du, Jiamu, Hale, Christopher J., Bischof, Sylvain, Feng, Suhua, Chodavarapu, Ramakrishna K., Zhong, Xuehua, Marson, Giuseppe, Pellegrini, Matteo, Segal, David J., Patel, Dinshaw J., Jacobsen, Steven E.

“…In Arabidopsis , the RNA-directed DNA methylation pathway is important for establishing and maintaining DNA methylation — here Pol V is shown to depend on…”
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Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases by Segal, David J, Büchel, Janine, Szczepek, Michal, Cathomen, Toni, Serrano, Luis, Brondani, Vincent

“…Artificial endonucleases consisting of a FokI cleavage domain tethered to engineered zinc-finger DNA-binding proteins have proven useful for stimulating…”
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Venous thromboembolism incidence in the Cooperative Study of Sickle Cell Disease by Naik, R. P., Streiff, M. B., Haywood, C., Segal, J. B., Lanzkron, S.

“…Summary Background Venous thromboembolism (VTE) has been recently recognized as a complication of sickle cell disease (SCD); however, the incidence of VTE in…”
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The promise of gene editing: so close and yet so perilously far by Segal, David J.

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Dr.Nod: computational framework for discovery of regulatory non-coding drivers in tissue-matched distal regulatory elements by Tomkova, Marketa, Tomek, Jakub, Chow, Julie, McPherson, John D, Segal, David J, Hormozdiari, Fereydoun

“…The discovery of cancer driver mutations is a fundamental goal in cancer research. While many cancer driver mutations have been discovered in the…”
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Modelling and simulation of micro-milling cutting forces by Afazov, S.M., Ratchev, S.M., Segal, J.

“…The paper presents a new approach for predicting micro-milling cutting forces using the finite element method (FEM). The trajectory of the tool and the uncut…”
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Bind-n-Seq: high-throughput analysis of in vitro protein-DNA interactions using massively parallel sequencing by Zykovich, Artem, Korf, Ian, Segal, David J

“…Transcription factor-DNA interactions are some of the most important processes in biology because they directly control hereditary information. The targets of…”
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Effects of micro-milling conditions on the cutting forces and process stability by Afazov, S.M., Zdebski, D., Ratchev, S.M., Segal, J., Liu, S.

“…Determining stable cutting conditions for corresponding cutting tools with specific geometries is essential for achieving precision micro-milling with high…”
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Design and fabrication of a hybrid alginate hydrogel/poly(ε‐caprolactone) mold for auricular cartilage reconstruction by Visscher, D. O., Gleadall, A., Buskermolen, J. K., Burla, F., Segal, J., Koenderink, G. H., Helder, M. N., van Zuijlen, P. P. M.

“…The aim of this study was to design and manufacture an easily assembled cartilage implant model for auricular reconstruction. First, the printing accuracy and…”
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Systematic review with meta‐analysis: the management of chronic refractory pouchitis with an evidence‐based treatment algorithm by Segal, J. P., Ding, N. S., Worley, G., Mclaughlin, S., Preston, S., Faiz, O. D., Clark, S. K., Hart, A. L.

“…Summary Background Restorative proctocolectomy with ileal pouch anal anastomosis (IPAA) is considered the procedure of choice in patients with ulcerative…”
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