Search Results - "J. F-X. Ainscough"

A Silencer Element Identified in Drosophila Is Required for Imprinting of H19 Reporter Transgenes in Mice by Brenton, J. D., Drewell, R. A., Viville, S., Hilton, K. J., Barton, S. C., J. F-X. Ainscough, Surani, M. A.

“…The H19 gene is subject to genomic imprinting because it is methylated and repressed after paternal inheritance and is unmethylated and expressed after…”
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Human menopausal and pregnant mare serum gonadotrophins in murine superovulation regimens for transgenic applications by Brooke, D.A., Orsi, N.M., Ainscough, J.F.X., Holwell, S.E., Markham, A.F., Coletta, P.L.

“…Superovulation is a fundamental procedure for generating transgenic rodents. While various methods exist, zygote yield/quality remain suboptimal, making these…”
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Clonal analysis of the late flowering fca mutant of Arabidopsis thaliana: cell fate and cell autonomy by Furner, I J, Ainscough, J F, Pumfrey, J A, Petty, L M

“…Plants that are homozygous for the fca mutation bolt and flower later than wild-type (FCA) plants. The mutation has little or no effect on the fate map of the…”
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Deletion of a silencer element disrupts H19 imprinting independently of a DNA methylation epigenetic switch by Drewell, R A, Brenton, J D, Ainscough, J F, Barton, S C, Hilton, K J, Arney, K L, Dandolo, L, Surani, M A

“…The H19 imprinted gene is silenced when paternally inherited and active only when inherited maternally. This is thought to involve a cis-acting control region…”
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Imprinting of Igf2 and H19 from a 130 kb YAC transgene by Ainscough, J F, Koide, T, Tada, M, Barton, S, Surani, M A

“…A stringent test for imprint control elements is to examine their function at ectopic loci in transgenic experiments. Igf2 and H19 are part of a larger…”
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Imprinted Expression of Neuronatin from Modified BAC Transgenes Reveals Regulation by Distinct and Distant Enhancers by John, Rosalind M., Aparicio, Samuel A.J.R., Ainscough, Justin F-X., Arney, Katharine L., Khosla, Sanjeev, Hawker, Kelvin, Hilton, Kathy J., Barton, Sheila C., Surani, M.Azim

“…Neuronatin (Nnat) is an imprinted gene that is expressed exclusively from the paternal allele while the maternal allele is silent and methylated. The Nnat…”
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A skeletal muscle-specific mouse Igf2 repressor lies 40 kb downstream of the gene by Ainscough, J F, John, R M, Barton, S C, Surani, M A

“…Igf2 and H19 are closely linked and reciprocally expressed genes on distal chromosome 7 in the mouse. We have previously shown that a 130 kb YAC transgene…”
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Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila by Erhardt, Sylvia, Lyko, Frank, Ainscough, Justin F-X, Surani, M Azim, Paro, Renato

“…A subset of autosomal genes undergo genomic imprinting which results in expression from only the paternal or maternal chromosome. While this phenomenon is…”
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Mechanism of imprinting on mouse distal chromosome 7 by Ainscough, J F, John, R M, Surani, M A

“…Genomic imprinting is an epigenetic mode of gene regulation that results in expression of the autosomal 'imprinted' genes from only a single allele, determined…”
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