Search Results - "J. Connolly, Richard"

Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy by Mukhopadhyay, Anandaroop, Wright, Jocelyn, Shirley, Shawna, Canton, David A., Burkart, Christoph, Connolly, Richard J., Campbell, Jean S., Pierce, Robert H.

“…Intratumoral electroporation-mediated IL-12 gene therapy (IT-pIL12/EP) has been shown to be safe and effective in clinical trials, demonstrating systemic…”
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Optimization of a plasma facilitated DNA delivery method by Connolly, Richard J., Hoff, Andrew M., Gilbert, Richard, Jaroszeski, Mark J.

“…Plasma-based methods have recently emerged as a technique for augmenting plasmid DNA delivery to skin. This delivery modality relies on the deposition of…”
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Characterization of plasma mediated molecular delivery to cells in vitro by Connolly, Richard J., Lopez, Gabriel A., Hoff, Andrew M., Jaroszeski, Mark J.

“…Ion-based strategies have recently emerged as a method to facilitate molecular delivery. These methods are attractive as they separate the applicator from the…”
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Plasma facilitated delivery of DNA to skin by Connolly, Richard J., Lopez, Gabriel A., Hoff, Andrew M., Jaroszeski, Mark J.

“…Non‐viral delivery of cell‐impermeant drugs and DNA in vivo has traditionally relied upon either chemical or physical stress applied directly to target…”
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An Integrated Architecture for Corrosion Monitoring and Testing, Data mining, Modeling and Diagnostics/Prognostics by Li, Honglei, Garvan, Margaret R, Li, Jiaming, Echauz, Javier, J. Vachtsevanos, George, W. Brown, Douglas, J. Connolly, Richard, Zahiri, Frank

“…It has been established that corrosion is one of the most important factors causing deterioration and decreased performance and reliability in critical…”
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S446 Nano-Pulse Stimulation Technology Is a Promising New Energy Modality for Barrett’s Esophagus by Ganz, Robert, Danitz, David J., Moss, Kevin, Hartman, Holly E., Levinson, Mitchell, Connolly, Richard J.

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Non-contact helium-based plasma for delivery of DNA vaccines: Enhancement of humoral and cellular immune responses by Connolly, Richard J., Chapman, Taryn, Hoff, Andrew M., Kutzler, Michele A., Jaroszeski, Mark J., Ugen, Kenneth E.

“…Non-viral in vivo administration of plasmid DNA for vaccines and immunotherapeutics has been hampered by inefficient delivery. Methods to enhance delivery such…”
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Effects of Pulsed Electric Fields on the Coronary Arteries in Swine by Ladejobi, Adetola, Christopoulos, Georgios, Tan, Nicholas, Ladas, Thomas P., Tri, Jason, van Zyl, Martin, Yasin, Omar, Sugrue, Alan, Khabsa, Mariam, Uecker, Darrin R., Connolly, Richard J., Danitz, David J., DeSimone, Christopher V., Killu, Ammar M., Maor, Elad, Holmes, David, Asirvatham, Samuel J., Del-Carpio Munoz, Freddy

“…Previous animal studies have shown no significant vascular injury from pulsed electrical field (PEF) ablation. We sought to assess the effect of PEF on swine…”
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Development of an adaptive electroporation system for intratumoral plasmid DNA delivery by Brown, Douglas W., Bahrami, Arya J., Canton, David A., Mukhopadhyay, Anandaroop, Campbell, Jean S., Pierce, Robert H., Connolly, Richard J.

“…Intratumoral electroporation of plasmid DNA encoding the proinflammatory cytokine interleukin 12 promotes innate and adaptive immune responses correlating with…”
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Reversible Atrioventricular Conduction Impairment Following Bipolar Nanosecond Electroporation of the Interventricular Septum by van Zyl, Martin, Ladejobi, Adetola O., Tri, Jason A., Yasin, Omar Z., Connolly, Richard J., Danitz, David J., DeSimone, Christopher V., Killu, Ammar M., Maor, Elad, Asirvatham, Samuel J.

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Direct Current Helium Plasma for In vivo Delivery of Plasmid DNA Encoding Erythropoietin to Murine Skin by Jaroszeski, Mark J, Harvey-Chapman, Taryn, Hoff, Andrew, Atkins, Reginald, Connolly, Richard J

“…The use of electric fields to deliver DNA, called electroporation, has the potential to broadly impact vaccination and disease treatment. The evidence for this…”
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Enhancement of antigen specific humoral immune responses after delivery of a DNA plasmid based vaccine through a contact-independent helium plasma by Connolly, Richard J, Rey, Jose I, Lambert, Vance M, Wegerif, Garrett, Jaroszeski, Mark J, Ugen, Kenneth E

“…Abstract Non-viral in vivo delivery of DNA, encoding for specific proteins, has traditionally relied on chemical or physical forces applied directly to…”
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Electrogenetherapy of B16.F10 murine melanoma tumors with an interleukin-28 expressing DNA plasmid by Shah, Kevin, Connolly, Richard J., Chapman, Taryn, Jaroszeski, Mark J., Ugen, Kenneth E.

“…Augmented delivery of cytokine-expressing DNA plasmids to subcutaneous tumors has been demonstrated to result in a level of enhanced anti-tumor activity. One…”
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Abstract B26: A novel applicator for endoscopic gene electrotransfer by Bahrami, Arya J., Connolly, Richard J., Campbell, Jean S., Pierce, Robert H.

“…Abstract Intratumoral gene delivery is a novel immunotherapy showing promise in cutaneous cancers such as melanoma. However, the broad application of this…”
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B-PO03-028 BIPOLAR PULSED ELECTRIC FIELD ABLATION OF THE INTERVENTRICULAR SEPTUM by van Zyl, Martin, Ladas, Thomas P., Yasin, Omar Z., Ladejobi, Adetola O., Tan, Nicholas Y.L., Christopoulos, Georgios, Tri, Jason A., Mariam, Khabsa, Richard, Connolly J., DeSimone, Christopher V., Killu, Ammar M., Asirvatham, Samuel J.

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B-IN02-03 USING PULSED ELECTRIC FIELDS TO CAUSE FOCAL FIBROSIS IN THE INTERVENTRICULAR SEPTUM by Ladas, Thomas P., van Zyl, Martin, Yick Loong Tan, Nicholas, Christopoulos, Georgios, Tri, Jason A., Yasin, Omar Ziad, Ladejobi, Adetola, Khabsa, Mariam, Connolly, Richard J., DeSimone, Christopher V., Killu, Ammar M., Maor, Elad, Asirvatham, Samuel J.

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B-PO01-092 USING PULSED ELECTRIC FIELDS TO CAUSE FOCAL FIBROSIS IN THE INTERVENTRICULAR SEPTUM by Ladas, Thomas P., van Zyl, Martin, Loong Tan, Nicholas Yick, Christopoulos, Georgios, Tri, Jason A., Yasin, Omar Ziad, Ladejobi, Adetola, Khabsa, Mariam, Connolly, Richard J., DeSimone, Christopher V., Killu, Ammar M., Maor, Elad, Asirvatham, Samuel J.

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Effects of Pulsed Electric Fields on the Coronary Arteries in Swine by Ladejobi, Adetola, Christopoulos, Georgios, Tan, Nicholas, Ladas, Thomas P., Tri, Jason, van Zyl, Martin, Yasin, Omar, Sugrue, Alan, Khabsa, Mariam, Uecker, Darrin R., Connolly, Richard J., Danitz, David J., DeSimone, Christopher V., Killu, Ammar M., Maor, Elad, Holmes, David, Asirvatham, Samuel J., Del-Carpio Munoz, Freddy

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B-PO04-124 EFFECTS OF PULSED ELECTRIC FIELDS ON THE CORONARY VASCULATURE IN SWINE by Christopoulos, Georgios, Ladejobi, Adetola, Tri, Jason, Tan, Nicholas Y., Ladas, Thomas P., Sugrue, Alan M., van Zyl, Martin, Yasin, Omar Z., Khabsa, Mariam, Uecker, Darrin, Connolly, Richard J., Danitz, David J., DeSimone, Christopher V., Killu, Ammar M., Maor, Elad, Munoz Freddy, Del-Carpio, Holmes, David R., Asirvatham, Samuel J.

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Abstract 1614: Intratumoral delivery of a P2A-linked bicistronic IL-12 construct leads to high intratumoral expression and systemic anti-tumor response by Canton, David A., Burkart, Christoph, Shirley, Shawna A., Mukhopadhyay, Anandaroop, Connolly, Richard J., Bahrami, Arya, Campbell, Jean S., Pierce, Robert H.

“…Abstract The use of immunomodulatory cytokines has been shown effective in regressing a wide range of tumors. However, systemic delivery of recombinant…”
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