Search Results - "J Rhodes, Nathaniel"

Vancomycin Area Under the Curve and Acute Kidney Injury: A Meta-analysis by Aljefri, Doaa M, Avedissian, Sean N, Rhodes, Nathaniel J, Postelnick, Michael J, Nguyen, Kevin, Scheetz, Marc H

“…Abstract Background This study analyzed the relationship between vancomycin area under the concentration-time curve (AUC) and acute kidney injury (AKI)…”
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Piperacillin-Tazobactam Added to Vancomycin Increases Risk for Acute Kidney Injury: Fact or Fiction? by Avedissian, Sean N, Pais, Gwendolyn M, Liu, Jiajun, Rhodes, Nathaniel J, Scheetz, Marc H

“…Abstract Vancomycin and piperacillin-tazobactam are 2 of the most commonly prescribed antibiotics in hospitals. Recent data from multiple meta-analyses suggest…”
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Vancomycin‐Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for Prevention by Pais, Gwendolyn M., Liu, Jiajun, Zepcan, Sanja, Avedissian, Sean N., Rhodes, Nathaniel J., Downes, Kevin J., Moorthy, Ganesh S., Scheetz, Marc H.

“…Vancomycin is a recommended therapy in multiple national guidelines. Despite the common use, there is a poor understanding of the mechanistic drivers and…”
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Lack of synergistic nephrotoxicity between vancomycin and piperacillin/tazobactam in a rat model and a confirmatory cellular model by Pais, Gwendolyn M, Liu, Jiajun, Avedissian, Sean N, Hiner, Danielle, Xanthos, Theodoros, Chalkias, Athanasios, d’Aloja, Ernesto, Locci, Emanuela, Gilchrist, Annette, Prozialeck, Walter C, Rhodes, Nathaniel J, Lodise, Thomas P, Fitzgerald, Julie C, Downes, Kevin J, Zuppa, Athena F, Scheetz, Marc H

“…Abstract Background Vancomycin and piperacillin/tazobactam are reported in clinical studies to increase acute kidney injury (AKI). However, no clinical study…”
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Comparative Performance of Urinary Biomarkers for Vancomycin-Induced Kidney Injury According to Timeline of Injury by Pais, Gwendolyn M, Avedissian, Sean N, O'Donnell, J Nicholas, Rhodes, Nathaniel J, Lodise, Thomas P, Prozialeck, Walter C, Lamar, Peter C, Cluff, Cameron, Gulati, Anil, Fitzgerald, Julie C, Downes, Kevin J, Zuppa, Athena F, Scheetz, Marc H

“…Urinary biomarkers are superior to serum creatinine for defining onset and extent of kidney injury. This study classifies the temporal predictive ability of…”
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Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes by Snider, Josephine B, Mithal, Leena B, Kwah, Jason H, Rhodes, Nathaniel J, Son, Moeun

“…To evaluate the choice of antibiotic used for intrapartum Group B Streptococcus (GBS) prophylaxis in pregnant individuals with reported penicillin allergies…”
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A Review of the Clinical Pharmacokinetics of Polymyxin B by Avedissian, Sean N, Liu, Jiajun, Rhodes, Nathaniel J, Lee, Andrew, Pais, Gwendolyn M, Hauser, Alan R, Scheetz, Marc H

“…Polymyxin B remains an antibiotic of last resort because of its toxicities. Although newer therapies are becoming available, it is anticipated that resistance…”
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In-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells by Avedissian, Sean N., Malik, Johid R., Podany, Anthony T., Neely, Michael, Rhodes, Nathaniel J., Scarsi, Kimberly K., Scheetz, Marc H., Duryee, Michael J., Modebelu, Ukamaka O., Mykris, Timothy M., Winchester, Lee C., Byrareddy, Siddappa N., Fletcher, Courtney V.

“…Three years after SARS-CoV-2 emerged as a global infectious threat, the virus has become endemic. The neurological complications such as depression, anxiety,…”
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Opportunities for antimicrobial stewardship among carbapenem-treated patients in 18 North American hospitals by Wagner, Jamie L., Rhodes, Nathaniel J., Scheetz, Marc H., Bosso, John A., Goff, Debra A., Rybak, Michael J., Davis, Susan L.

“…Here we describe the characteristics of carbapenem use at 18 hospitals across North America. Adult inpatients treated with a carbapenem for ≥24 h were included…”
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Genomics of Aminoglycoside Resistance in Pseudomonas aeruginosa Bloodstream Infections at a United States Academic Hospital by Atassi, Giancarlo, Medernach, Rachel, Scheetz, Marc, Nozick, Sophia, Rhodes, Nathaniel J, Murphy-Belcaster, Megan, Murphy, Katherine R, Alisoltani, Arghavan, Ozer, Egon A, Hauser, Alan R

“…Pseudomonas aeruginosa frequently becomes resistant to aminoglycosides by the acquisition of aminoglycoside modifying enzyme (AME) genes and the occurrence of…”
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Trends in and Predictors of Carbapenem Consumption across North American Hospitals: Results from a Multicenter Survey by the MAD-ID Research Network by Rhodes, Nathaniel J, Wagner, Jamie L, Davis, Susan L, Bosso, John A, Goff, Debra A, Rybak, Michael J, Scheetz, Marc H

“…We sought to define trends in and predictors of carbapenem consumption across community, teaching, and university-affiliated hospitals in the United States and…”
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Dose, duration, and animal sex predict vancomycin-associated acute kidney injury in preclinical studies by O'Donnell, J. Nicholas, Rhodes, Nathaniel J., Miglis, Cristina M., Catovic, Lejla, Liu, Jiajun, Cluff, Cameron, Pais, Gwendolyn, Avedissian, Sean, Joshi, Medha D., Griffin, Brooke, Prozialeck, Walter, Gulati, Anil, Lodise, Thomas P., Scheetz, Marc H.

“…•We analysed preclinical studies on vancomycin–associated acute kidney injury (AKI).•Dose-response data were compiled at the individual animal level to assess…”
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Discrepancies Between Patient Self-Reported and Electronic Health Record Documentation of Medication Allergies and Adverse Reactions in the Acute Care Setting: Room for Improvement by Kabakov, Anna, Rhodes, Nathaniel J., Wenzel, Richard

“…Background: Allergy information is commonly transcribed into an electronic health record (EHR) for all patients admitted to acute care hospital units by a…”
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Effect of omadacycline alone and in combination with meropenem against carbapenem-resistant Acinetobacter baumannii isolates by O'Donnell, J. Nicholas, Putra, Vibert, Maring, Brittney L., Ozer, Egon A., Belfiore, Gina M., Rhodes, Nathaniel J.

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An exploratory analysis of the ability of a cefepime trough concentration greater than 22 mg/L to predict neurotoxicity by Rhodes, Nathaniel J, Kuti, Joseph L, Nicolau, David P, Neely, Michael N, Nicasio, Anthony M, Scheetz, Marc H

“…Abstract Introduction Cefepime trough concentrations >22 mg/L (T>22 ) have been associated with neurotoxicity in a single study. Patients and methods…”
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Multidrug resistant Aeromonas infection following medical leech therapy: A case report and development of a joint antimicrobial stewardship and infection prevention protocol by Masters, Mary Clare, Gupta, Aakash R., Rhodes, Nathaniel J., Flaherty, John P., Zembower, Teresa R., Alghoul, Mohammed, Krueger, Karen M.

“…•Aeromonas sp. infections are a recognized complication of medical leech therapy.•Antimicrobial prophylaxis is typically used for patients having medical leech…”
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Implementation of an Extended-Infusion Piperacillin-Tazobactam Dosing Protocol: Unexpected Findings when Monitoring Safety and Compliance with Smart Pump Technology by J Rhodes, Nathaniel, Lopez, Jenna, K Pham, Cecilia, Brake, Helga, Fotis, Michael, E Harpe, Spencer, Avedissian, Sean, H Scheetz, Marc

“…Compliance with recommended infusion rates was evaluated before, during, and after the implementation of extended-infusion (EI) piperacillin-tazobactam at an…”
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Clinical pharmacokinetics of ceftolozane and tazobactam in an obese patient receiving continuous venovenous haemodiafiltration: A patient case and literature review by Mahmoud, Ahmed, Shah, Anooj, Nutley, Kaitlin, Nicolau, David P., Sutherland, Christina, Jain, Manu, Scheetz, Marc H., Rhodes, Nathaniel J.

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Eight unexpected cases of vancomycin associated acute kidney injury with contemporary dosing by O'Donnell, J. Nicholas, Ghossein, Cybele, Rhodes, Nathaniel J, Peng, Jessica, Lertharakul, Tina, Pham, C. Kim, Scheetz, Marc H

“…Abstract Vancomycin is one of the most commonly utilized antibiotics in US hospitals. It remains the drug of choice for the treatment of serious infections…”
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Impact of body mass index on clinical outcomes in patients with gram-negative bacteria bloodstream infections by Lizza, Bryan D, Rhodes, Nathaniel J, Esterly, John S, Toy, Carolyn, Lopez, Jenna, Scheetz, Marc H

“…Abstract Introduction Excess body mass index (BMI) is associated with a higher risk of death in many disease states, yet less is known about the impact of…”
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