Search Results - "J Downer"

Role of Cannabinoids in Inflammation by Downer, Eric J

“…This Special Issue brings an update on some of the advances in research in the cannabinoid field, with focus on the impact of cannabinoids on inflammation…”
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The role of cannabinoids in adult neurogenesis by Prenderville, Jack A, Kelly, Áine M, Downer, Eric J

“…The processes underpinning post‐developmental neurogenesis in the mammalian brain continue to be defined. Such processes involve the proliferation of neural…”
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Inhibiting neuroinflammation: The role and therapeutic potential of GABA in neuro-immune interactions by Crowley, Tadhg, Cryan, John F, Downer, Eric J, O’Leary, Olivia F

“…Highlights • Inflammatory stimuli decrease GABAergic neuron density and GAD65/67. • Inflammatory mediators modulate conductance and expression of GABAA…”
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Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis by Fitzpatrick, John-Mark, Hackett, Becky, Costelloe, Lisa, Hind, William, Downer, Eric J.

“…The innate immune response to bacterial and viral molecules involves the coordinated production of cytokines, chemokines, and type I interferons (IFNs), which…”
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Local anaesthetic thoracoscopy: British Thoracic Society Pleural Disease Guideline 2010 by Rahman, Najib M, Ali, Nabeel J, Brown, Gail, Chapman, Stephen J, Davies, Robert J O, Downer, Nicola J, Gleeson, Fergus V, Howes, Timothy Q, Treasure, Tom, Singh, Shivani, Phillips, Gerrard D

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Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro by Lyons, Anthony, Lynch, Aileen M, Downer, Eric J, Hanley, Riona, O'Sullivan, Joan B, Smith, Andrew, Lynch, Marina A

“…Several neurodegenerative disorders are associated with evidence of inflammation, one feature of which is increased activation of microglia, the most likely…”
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Neuropathic orofacial pain: Cannabinoids as a therapeutic avenue by McDonough, Patrick, McKenna, Joseph P., McCreary, Christine, Downer, Eric J.

“…•NOP disorders represent a clinical challenge since pain can arise from many sources in the orofacial region.•The pathophysiology of NOP is unclear and…”
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Gαq takes centre stage in multiple sclerosis pathogenesis by Downer, Eric J

“…There is no cure for multiple sclerosis （MS）; however, a number of strategies exist for disease management, including medications that reduce the frequency of…”
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An efficacy and safety comparison between different stentriever designs in acute ischaemic stroke: a systematic review and meta-analysis by Grech, R, Pullicino, R, Thornton, J, Downer, J

“…Aim To assess the recanalisation rates and long-term functional outcomes of the Solitaire and Trevo devices; to compare these results to those from the…”
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Cannabinoids and innate immunity: taking a toll on neuroinflammation by Downer, Eric J

“…The biologically active components of cannabis have therapeutic potential in neuroinflammatory disorders due to their anti-inflammatory propensity…”
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Two-Phase Flow Boiling of Nanofluids in Mini- and Microchannels by Kabir, M., Downer, J., Preller, E., Tarau, C., Yang, B., Xu, J.

“…The effects of single-phase nanofluid flow in mini-/microchannels have been investigated both experimentally and numerically in the literature during the last…”
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Cannabidiol modulation of oxidative stress and signalling by Pereira, Sónia R., Hackett, Becky, O’Driscoll, David N., Sun, Melody Cui, Downer, Eric J.

“…Abstract Cannabidiol (CBD), one of the primary non-euphoric components in the Cannabis sativa L. plant, has undergone clinical development over the last number…”
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The Silk Vista Baby – The UK experience by Bhogal, P, Makalanda, HLD, Wong, K, Keston, P, Downer, J, Du Plessis, JC, Nania, A, Simonato, D, Fuschi, M, Chong, W, O’Reilly, S, Rennie, I

“…Background The Silk Vista Baby (SVB) flow diverter (FDS) is the only FDS deliverable via a 0.017 inch microcatheter and is specifically designed for the distal…”
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A Survey of tooth morphology teaching methods employed in the United Kingdom and Ireland by Lone, M., McKenna, J. P., Cryan, J. F., Downer, E. J., Toulouse, A.

“…Background Tooth morphology is a central component of the dental curriculum and is applicable to all dental specialities. Traditional teaching methods are…”
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Impact of Exercise on Innate Immunity in Multiple Sclerosis Progression and Symptomatology by Barry, Alison, Cronin, Owen, Ryan, Aisling M, Sweeney, Brian, Yap, Siew M, O'Toole, Orna, Allen, Andrew P, Clarke, Gerard, O'Halloran, Ken D, Downer, Eric J

“…Multiple Sclerosis (MS), an idiopathic progressive immune-mediated neurological disorder of the central nervous system (CNS), is characterized by recurrent…”
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Safety, feasibility, and efficacy of rTMS for major depression in borderline personality disorder: A 2-case report by Feffer, K, Giacobbe, P, Fettes, P, Downer, J

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Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia by Lyons, Anthony, Downer, Eric J, Costello, Derek A, Murphy, Niamh, Lynch, Marina A

“…The interaction between the membrane glycoprotein, CD200 and its cognate receptor CD200 receptor (CD200R), has been shown to play a role in maintaining…”
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Assessment of Thiel‐Embalmed Cadavers as a Teaching Tool for Oral Anatomy and Local Anesthesia by Lone, Mutahira, McKenna, Joseph P., Balta, Joy Y., O'Mahony, Siobhain M., Cryan, John F., Downer, Eric J., Toulouse, André

“…The aim of this study was to determine whether Thiel‐embalmed cadavers would provide a useful anatomy teaching tool for topics that cannot be approached using…”
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A reversible cause of bilateral thalamic infarct and cognitive impairment by Ng, Y.S, Downer, J, Keston, P, Derry, C

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Anti-inflammatory Potential of Terpenes Present in Cannabis sativa L by Downer, Eric J

“…Cannabis sativa L. (C. sativa) contains an array of plant-derived (phyto) cannabinoids and terpenes that are predominantly located in the trichome cavity of…”
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