Search Results - "J Daniels, David"

Treatment Strategies in Diffuse Midline Gliomas With the H3K27M Mutation: The Role of Convection-Enhanced Delivery in Overcoming Anatomic Challenges by Himes, Benjamin T, Zhang, Liang, Daniels, David J

“…Diffuse midline gliomas harboring the H3 K27M mutation-including the previously named diffuse intrinsic pontine glioma (DIPG)-are lethal high-grade pediatric…”
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Chorioallantoic membrane (CAM) assay to study treatment effects in diffuse intrinsic pontine glioma by Power, Erica A, Fernandez-Torres, Jenelys, Zhang, Liang, Yaun, Ruiyi, Lucien, Fabrice, Daniels, David J

“…Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain tumor. While there are a number of in vivo rodent models for evaluating tumor biology and…”
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Combining Electromagnetic Spectroscopy and Ground-Penetrating Radar for the Detection of Anti-Personnel Landmines by A Marsh, Liam, van Verre, Wouter, L Davidson, John, Gao, Xianyang, J W Podd, Frank, J Daniels, David, J Peyton, Anthony

“…Dual mode detectors combining metal detection and ground-penetrating radar are increasingly being used during humanitarian demining operations because of their…”
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Comparison on epidemiology, tumor location, histology, and prognosis of intracranial germ cell tumors between Mayo Clinic and Japanese consortium cohorts by Takami, Hirokazu, Perry, Avital, Graffeo, Christopher S, Giannini, Caterina, Narita, Yoshitaka, Nakazato, Yoichi, Saito, Nobuhito, Nishikawa, Ryo, Matsutani, Masao, Ichimura, Koichi, Daniels, David J

“…Central nervous system (CNS) germ cell tumors (GCTs) are rare malignant neoplasms that arise predominantly in adolescents and young adults. CNS GCTs…”
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Novel Diagnostic Methods and Posttreatment Clinical Phenotypes Among Intracranial Germ Cell Tumors by Takami, Hirokazu, Perry, Avital, Graffeo, Christopher S, Giannini, Caterina, Daniels, David J

“…Abstract BACKGROUND Central nervous system (CNS) germ cell tumors (GCT) are rare and complex pediatric neoplasms, the optimal management of which remains an…”
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Efficacy and safety of bevacizumab for vestibular schwannoma in neurofibromatosis type 2: a systematic review and meta-analysis of treatment outcomes by Lu, Victor M., Ravindran, Krishnan, Graffeo, Christopher S., Perry, Avital, Van Gompel, Jamie J., Daniels, David J., Link, Michael J.

“…Background Individual evidence suggests that the anti-angiogenic agent bevacizumab may control vestibular schwannoma (VS) growth and promote hearing…”
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Epidemiology, natural history, and optimal management of neurohypophyseal germ cell tumors by Takami, Hirokazu, Graffeo, Christopher S, Perry, Avital, Giannini, Caterina, Daniels, David J

“…Intracranial germ cell tumors (iGCTs) often arise at the neurohypophysis, their second most common origination, following the pineal region. Neurohypophyseal…”
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H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers by Fang, Dong, Gan, Haiyun, Cheng, Liang, Lee, Jeong-Heon, Zhou, Hui, Sarkaria, Jann N, Daniels, David J, Zhang, Zhiguo

“…Expression of histone H3.3K27M mutant proteins in human diffuse intrinsic pontine glioma (DIPG) results in a global reduction of tri-methylation of H3K27…”
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Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane by Kumar, Ravi, de Mooij, Tristan, Peterson, Timothy E, Kaptzan, Tatiana, Johnson, Aaron J, Daniels, David J, Parney, Ian F

“…Glioblastoma is the most common primary tumor of the brain and has few long-term survivors. The local and systemic immunosuppressive environment created by…”
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Reirradiation for diffuse intrinsic pontine glioma: a systematic review and meta-analysis by Lu, Victor M., Welby, John P., Mahajan, Anita, Laack, Nadia N., Daniels, David J.

“…Background Diffuse intrinsic pontine glioma (DIPG) is a pediatric brain tumor with dismal prognosis despite initial radiation therapy (RT). The clinical…”
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The Third Eye Sees Double: Cohort Study of Clinical Presentation, Histology, Surgical Approaches, and Ophthalmic Outcomes in Pineal Region Germ Cell Tumors by Takami, Hirokazu, Graffeo, Christopher S., Perry, Avital, Giannini, Caterina, Daniels, David J.

“…Intracranial germ cell tumors (GCTs) predominantly occur in the adolescent and young adult population and are most frequently located at the pineal gland…”
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Status Quo and Trends of Intra-Arterial Therapy for Brain Tumors: A Bibliometric and Clinical Trials Analysis by Rechberger, Julian S., Thiele, Frederic, Daniels, David J.

“…Intra-arterial drug delivery circumvents the first-pass effect and is believed to increase both efficacy and tolerability of primary and metastatic brain tumor…”
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Antitumor activity of novel pyrazole-based small molecular inhibitors of the STAT3 pathway in patient derived high grade glioma cells by Zhang, Liang, Peterson, Timothy E, Lu, Victor M, Parney, Ian F, Daniels, David J

“…Abnormal activation of signal transducer and activator of transcription 3 (STAT3) transcription factor has been observed in many human cancers with roles in…”
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H3K27-altered diffuse midline glioma: a paradigm shifting opportunity in direct delivery of targeted therapeutics by Rechberger, Julian S, Power, Blake T, Power, Erica A, Nesvick, Cody L, Daniels, David J

“…Despite much progress, the prognosis for H3K27-altered diffuse midline glioma (DMG), previously known as diffuse intrinsic pontine glioma when located in the…”
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Nanoparticle Strategies to Improve the Delivery of Anticancer Drugs across the Blood-Brain Barrier to Treat Brain Tumors by Vanbilloen, Wouter J F, Rechberger, Julian S, Anderson, Jacob B, Nonnenbroich, Leo F, Zhang, Liang, Daniels, David J

“…Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms that occur within the brain and spinal cord. Although significant…”
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Histopathology and prognosis of germ cell tumors metastatic to brain: cohort study by Takami, Hirokazu, Graffeo, Christopher S., Perry, Avital, Ohno, Makoto, Ishida, Joji, Giannini, Caterina, Narita, Yoshitaka, Nakazato, Yoichi, Saito, Nobuhito, Nishikawa, Ryo, Matsutani, Masao, Ichimura, Koichi, Daniels, David J.

“…Introduction Germ cell tumors (GCTs) are uncommon neoplasms predominantly arising in midline tissues. The prognostic significance of histopathology in…”
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Opioid-Induced Tolerance and Dependence in Mice Is Modulated by the Distance between Pharmacophores in a Bivalent Ligand Series by David J. Daniels, Natalie R. Lenard, Chris L. Etienne, Law, Ping-Yee, Sandra C. Roerig, Portoghese, Philip S.

“…Given the mounting evidence for involvement of δ opioid receptors in the tolerance and physical dependence of μ opioid receptor agonists, we have investigated…”
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Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas by Welby, John P, Kaptzan, Tatiana, Wohl, Anton, Peterson, Timothy E, Raghunathan, Aditya, Brown, Desmond A, Gupta, Shiv K, Zhang, Liang, Daniels, David J

“…Diffuse Midline Gliomas with Histone 3-Lysine-27-Methionine (H3K27M) mutation constitute the majority of Diffuse Intrinsic Pontine Glioma (DIPG), which is the…”
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A multicenter analysis of the prognostic value of histone H3 K27M mutation in adult high-grade spinal glioma by Akinduro, Oluwaseun O, Garcia, Diogo P, Higgins, Dominique M O, Vivas-Buitrago, Tito, Jentoft, Mark, Solomon, David A, Daniels, David J, Pennington, Zach, Sherman, Wendy J, Delgardo, Mychael, Bydon, Mohamad, Kalani, Maziyar A, Zanazzi, George, Tsankova, Nadejda, Bendok, Bernard R, McCormick, Paul C, Sciubba, Daniel M, Lo, Sheng-Fu Larry, Clarke, Jennifer L, Abode-Iyamah, Kingsley, Quiñones-Hinojosa, Alfredo

“…High-grade spinal glioma (HGSG) is a rare but aggressive tumor that occurs in both adults and children. Histone H3 K27M mutation correlates with poor prognosis…”
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Impact of tumor markers on diagnosis, treatment and prognosis in CNS germ cell tumors: correlations with clinical practice and histopathology by Takami, Hirokazu, Graffeo, Christopher S., Perry, Avital, Giannini, Caterina, Nakazato, Yoichi, Saito, Nobuhito, Matsutani, Masao, Nishikawa, Ryo, Daniels, David J., Ichimura, Koichi

“…Tumor markers in CNS germ cell tumors (GCTs) include human chorionic gonadotropin (HCG) and alpha fetoprotein (AFP), which have significant diagnostic…”
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