Search Results - "J C Lawrence, Jr"

PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation by Lin, Tai-An, Kong, Xianming, Timothy A. J. Haystead, Pause, Arnim, Belsham, Graham, Sonenberg, Nahum, Lawrence, John C.

“…PHAS-I is a heat-stable protein (relative molecular mass $\approx$12,400) found in many tissues. It is rapidly phosphorylated in rat adipocytes incubated with…”
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cAMP- and Rapamycin-Sensitive Regulation of the Association of Eukaryotic Initiation Factor 4E and the Translational Regulator PHAS-I in Aortic Smooth Muscle Cells by Graves, Lee M., Bornfeldt, Karin E., Argast, Gretchen M., Krebs, Edwin G., Kong, Xianming, Lin, Tai An, Lawrence, John C.

“…Incubating rat aortic smooth muscle cells with either platelet-derived growth factor BB (PDGF) or insulin-like growth factor I (IGF-I) increased the…”
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Isoproterenol Stimulates Phosphorylation of the Insulin-Regulatable Glucose Transporter in Rat Adipocytes by James, David E., Hiken, Jeffrey, Lawrence, John C.

“…We have examined the acute effects of insulin and isoproterenol on the phosphorylation state of the insulin-regulatable glucose transporter (IRGT) in rat…”
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Increased Glycogen Accumulation in Transgenic Mice Overexpressing Glycogen Synthase in Skeletal Muscle by Manchester, Jill, Skurat, Alexander V., Roach, Peter, Hauschka, Stephen D., Lawrence, John C.

“…To investigate the role of glycogen synthase in controlling glycogen accumulation, we generated three lines of transgenic mice in which the enzyme was…”
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Molecular Cloning and Tissue Distribution of PHAS-I, an Intracellular Target for Insulin and Growth Factors by Hu, Chaobin, Pang, Suhong, Kong, Xianming, Velleca, Mark, Lawrence, John C.

“…Although the actions of insulin and a number of growth factors that signal via protein-tyrosine kinase receptors are believed to involve increased…”
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Regulation of Phosphorylation of Nicotinic Acetylcholine Receptors in Mouse BC3H1 Myocytes by Smith, McHardy M., Merlie, John P., Lawrence, John C.

“…By using 32P-labeling methods and performing immunoprecipitations with specific antibodies, we have found that three subunits of the nicotinic acetylcholine…”
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Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin by Brunn, Gregory J., Hudson, Christine C., Sekulić, Aleksandar, Williams, Josie M., Hosoi, Hajime, Houghton, Peter J., Lawrence, John C., Abraham, Robert T.

“…The immunosuppressant rapamycin interferes with G$_1$-phase progression in lymphoid and other cell types by inhibiting the function of the mammalian target of…”
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Insulin Stimulates Dephosphorylation of Phosphorylase in Rat Epitrochlearis Muscles by Zhang, J N, Hiken, J, Davis, A E, Lawrence, J C

“…We have investigated the effects of insulin on the phosphorylation of glycogen Phosphorylase in skeletal muscle. Rat epitrochlearis muscles were incubated in…”
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Stimulation of glucose transport and glucose transporter phosphorylation by okadaic acid in rat adipocytes by Lawrence, J C, Hiken, J F, James, D E

“…Okadaic acid, an inhibitor of Type I and IIa protein phosphatases, was recently found to stimulate 2-deoxyglucose uptake in rat adipocytes (Haystead, T. A. J.,…”
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Increasing cAMP Attenuates Activation of Mitogen-Activated Protein Kinase by Sevetson, Bradley R., Kong, Xianming, Lawrence, John C.

“…Activation of the mitogen-activated protein kinase (MAP kinase) isoforms ERK1 and ERK2 was investigated in rat adipocytes. Kinase activities were measured by…”
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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function by Pause, Arnim, Belsham, Graham J, Gingras, Anne-Claude, Donzé, Olivier, Lin, Tai-An, Lawrence, John C, Sonenberg, Nahum

“…The cloning is described of two related human complementary DNAs encoding polypeptides that interact specifically with the translation initiation factor…”
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Multiple Mechanisms Control Phosphorylation of PHAS-I in Five (S/T)P Sites That Govern Translational Repression by Mothe-Satney, Isabelle, Yang, Daqing, Fadden, Patrick, Haystead, Timothy A. J., Lawrence, John C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ras Signaling in the Activation of Glucose Transport by Insulin by Manchester, Jill, Kong, Xianming, Lowry, Oliver H., Lawrence, John C.

“…An approach involving microinjection and microanalysis has been developed to investigate signaltransduction pathways involved in the hormonal control of…”
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PHAS/4E-BPs as regulators of mRNA translation and cell proliferation by Lawrence, John C., Abraham, Robert T.

“…Insulin and growth factors elicit rapid increases in protein synthesis by stimulating mRNA translation. PHAS/4E-BPs, a recently discovered family of…”
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Insulin stimulates protein synthesis in skeletal muscle by enhancing the association of eIF-4E and eIF-4G by Kimball, S R, Jurasinski, C V, Lawrence, Jr, J C, Jefferson, L S

“…Insulin stimulated protein synthesis in gastrocnemius muscle of perfused rat hindlimb preparations by approximately twofold. The stimulation of protein…”
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Phosphorylation of the glucose transporter in rat adipocytes. Identification of the intracellular domain at the carboxyl terminus as a target for phosphorylation in intact-cells and in vitro by J C Lawrence, Jr, J F Hiken, D E James

“…Phosphorylation of the insulin-regulatable glucose transporter (IRGT) is increased by incubating rat adipocytes with isoproterenol or by incubating microsomal…”
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Glucose transport in L6 myoblasts overexpressing GLUT1 and GLUT4 by R Robinson, L J Robinson, D E James, J C Lawrence, Jr

“…The roles of the glucose transporter isoforms, GLUT1 and GLUT4, in mediating insulin-stimulated glucose transport were investigated by stably overexpressing…”
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Identification of Phosphorylation Sites in the Translational Regulator, PHAS-I, That Are Controlled by Insulin and Rapamycin in Rat Adipocytes by Fadden, P, Haystead, T A, Lawrence, Jr, J C

“…Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase in vitro decreased PHAS-I binding to eukaryotic initiation factor (eIF)-4E. The decrease in…”
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Brain extract induces synaptic characteristics in the basal lamina of cultured myotubes by Sanes, JR, Feldman, DH, Cheney, JM, Lawrence, JC, Jr

“…The basal lamina (BL) that occupies the synaptic cleft of the skeletal neuromuscular junction is antigenically distinct from extrasynaptic muscle fiber BL,…”
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Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway by Lin, T A, Kong, X, Saltiel, A R, Blackshear, P J, Lawrence, Jr, J C

“…PHAS-I levels increased 8-fold as 3T3-L1 fibroblasts differentiated into adipocytes and acquired sensitivity to insulin. Insulin increased PHAS-I protein…”
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