Search Results - "Júnior, Roberto César Pereira Lima"

Blockage of the fractalkine pathway reduces hyperalgesia and prevents morphological glial alterations—Comparison between inflammatory and neuropathic orofacial pain in male rats by Lisboa, Mario Roberto Pontes, Pereira, Anamaria Falcão, Alves, Bruno Wesley de Freitas, Dias, Diego Bernarde Souza, Alves, Luiza Clertiani Vieira, da Silva, Cristiane Maria Pereira, Lima‐Júnior, Roberto César Pereira, Gondim, Delane Viana, Vale, Mariana Lima

“…This study aimed to evaluate the effects of inhibitors of the fractalkine pathway in hyperalgesia in inflammatory and neuropathic orofacial pain in male rats…”
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Umbelliferone reduces inflammation and ligature‐induced osteoclastic alveolar bone resorption in mice by Tavares, Samia Jessica Silva, Pereira, Camila Rodrigues, Fortes, Roseane Aline Monteiro, Alves, Bianca Elen Souza, Fonteles, Cristiane Sá Roriz, Wong, Deysi Viviana Tenazoa, Lima‐Júnior, Roberto César Pereira, Moraes, Manoel Odorico, Lima, Vilma

“…Aims This study aimed to investigate the effects of Umbelliferone (UMB) on the inflammation underlying alveolar bone resorption in mouse periodontitis. Methods…”
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Is There an Interplay between Environmental Factors, Microbiota Imbalance, and Cancer Chemotherapy-Associated Intestinal Mucositis? by Fernandes, Camila, Miranda, Mahara Coelho Crisostomo, Roque, Cássia Rodrigues, Paguada, Ana Lizeth Padilla, Mota, Carlos Adrian Rodrigues, Florêncio, Katharine Gurgel Dias, Pereira, Anamaria Falcão, Wong, Deysi Viviana Tenazoa, Oriá, Reinaldo Barreto, Lima-Júnior, Roberto César Pereira

“…Interindividual variation in drug efficacy and toxicity is a significant problem, potentially leading to adverse clinical and economic public health outcomes…”
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Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation by Leal, Luzia Kalyne Almeida Moreira, Wong, Deysi Viviana Tenazoa, Araújo, Emmanuel Vinicius Oliveira, Freitas, Lyara Barbosa Nogueira, Rocha, Talita Magalhães, da Fonseca, Francisco Noé, de Araújo Lopes, Amanda, Lima Júnior, Roberto César Pereira

“…Contact dermatitis produces an inflammatory reaction primarily via stimulation of keratinocytes and cells of the immune system, which promote the release of…”
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Oleanolic Acid, a Pentacyclic Triterpene Attenuates the Mustard Oil-Induced Colonic Nociception in Mice by Maia, Juliana Lemos, Lima-Júnior, Roberto César Pereira, David, Juceni Pereira, David, Jorge Mauricio, Santos, Flávia Almeida, Rao, Vietla Satyanarayana

“…Many natural terpenoid compounds from plants exhibit antinociceptive property but very few studies have addressed their efficacy in visceral models of…”
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Editorial: Global excellence in inflammatory diseases: Latin America 2021 by Lima-Júnior, Roberto César Pereira, Crispín, José C., Brito, Gerly Anne Castro

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Oral carcinogenesis triggers a nociceptive behavior and c‐Fos expression in rats’ trigeminal pathway by Alves, Joana Maria dos Santos, Viana, Khalil Fernandes, Pereira, Anamaria Falcão, Lima Júnior, Roberto César Pereira, Vale, Mariana Lima, Pereira, Karuza Maria Alves, Gondim, Delane Viana

“…Objective To recognize changes that occur along the trigeminal pathway in oral cancer in order to establish an effective approach to pain control. Methods…”
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Polysaccharide-rich extract of Genipa americana leaves protects seizures and oxidative stress in the mice model of pentylenetetrazole-induced epilepsy by Nonato, Dayanne Terra Tenório, Aragão, Gislei Frota, Craveiro, Raquel Magalhães Castelo Branco, Pereira, Maria Gonçalves, Vasconcelos, Silvânia Maria Mendes, Wong, Deysi Viviana Tenazoa, Júnior, Roberto César Pereira Lima, Soares, Pedro Marcos Gomes, Lima, Marcos Aurélio de Sousa, Assreuy, Ana Maria Sampaio, Chaves, Edna Maria Camelo

“…Plant polysaccharides have biological activities in the brain and those obtained from Genipa americana leaves present antioxidant and anticonvulsant effects in…”
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Metformin reduces c-Fos and ATF3 expression in the dorsal root ganglia and protects against oxaliplatin-induced peripheral sensory neuropathy in mice by Pereira, Anamaria Falcão, Pereira, Lus Mário Silva, Silva, Cristiane Maria Pereira, Freitas Alves, Bruno Wesley, Barbosa, Jéssica Sales, Pinto, Francisco Maxwell Martins, Pereira, Ana Carolina, Silva, Karla Oliveira, Pontes, Renata Bessa, Alencar, Nylane Maria Nunes, Lima-Júnior, Roberto César Pereira, Vale, Mariana Lima

“…•Metformin protects against oxaliplatin-induced peripheral sensory neuropathy.•Metformin reduces the expression of c-Fos and ATF3 in the dorsal root…”
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Effect of different doses of zoledronic acid in establishing of bisphosphonate-related osteonecrosis by Silva, Paulo Goberlânio de Barros, Ferreira Junior, Antonio Ernando Carlos, Teófilo, Carolina Rodrigues, Barbosa, Maritza Cavalcante, Lima Júnior, Roberto César Pereira, Sousa, Fabrício Bitú, Mota, Mário Rogério Lima, Ribeiro, Ronaldo de Albuquerque, Alves, Ana Paula Negreiros Nunes

“…Abstract Objectives To establish osteonecrosis of the jaws in rats treated with different doses of zoledronic acid (ZA). Methods Male Wistar rats ( n = 6–7)…”
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SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4 by Wong, Deysi Viviana Tenazoa, Ribeiro-Filho, Helder Veras, Wanderley, Carlos Wagner Souza, Leite, Caio Abner Vitorino Gonçalves, Lima, Jonilson Berlink, Assef, Alexia Nathália Brígido, Cajado, Aurilene Gomes, Batista, Gabriela Loiola Ponte, González, Rafael Holanda, Silva, Karla Oliveira, Borges, Luis Philipi Carvalho, Alencar, Nylane Maria Nunes, Wilke, Diego Veras, Cunha, Thiago Mattar, Figueira, Ana Carolina Migliorini, Cunha, Fernando Queiroz, Lima-Júnior, Roberto César Pereira

“…Purpose Anticancer-drug efficacy seems to involve the direct interaction with host immune cells. Although topoisomerase I (Top I) inhibitors have been…”
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Inhibition of neutrophil migration and reduction of oxidative stress by ethyl p-coumarate in acute and chronic inflammatory models by Filho, Antônio Carlos Melo Lima, Silva, Irismara Sousa, Sousa, Francisca Beatriz Melo, de Souza, Luan Kelves Miranda, Gomes, Bruno da Silva, Gonçalves, Rodrigo Lopes Gomes, de Rezende, Diana Carvalho, Cunha, Francisco Valmor Macedo, Wong, Deysi Viviana Tenazoa, Júnior, Roberto César Pereira Lima, Medeiros, Jand Venes-Rolim, de Sousa, Damião Pergentino, Oliveira, Francisco de Assis

“…•Ethyl p-coumarate reduced inflammatory and stress oxidative parameters.•Ethyl p-coumarate reduced the proinflammatory cytokines (IL-6 and IL-8).•Ethyl…”
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A Novel Murine Model of a High Dose Brachytherapy-Induced Actinic Proctitis by Leite, Carlos Heli Bezerra, Lopes, Carlos Diego Holanda, Leite, Caio Abner Vitorino Gonçalves, Terceiro, Dulce Andrade, Lima, Gabriel Silva, Freitas, Jéssica Andrade, Cunha, Fernando Queiroz, Almeida, Paulo Roberto Carvalho, Wong, Deysi Viviana Tenazoa, Lima-Júnior, Roberto César Pereira

“…Radiation proctitis affects 1-20% of cancer patients undergoing radiation exposure due to pelvic malignancies, including prostate, gynecological and rectum…”
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Neutrophils contribute to the pathogenesis of hemorrhagic cystitis induced by ifosfamide by Dornelas-Filho, Amílcar Figueiredo, Pereira, Venúcia Bruna Magalhães, Wong, Deysi Viviana Tenazoa, Nobre, Lívia Maria Soares, Melo, Anielle Torres, Silva, Camila Meirelles Souza, Wanderley, Carlos Wagner Souza, Nour, Mariana Lima, Araújo, Lis Caetano Nobrega Costa, Silva, Renan Oliveira, Pinto, Francisco Maxwell Martins, Bingana, Rudy Diavila, Souza, Marcellus Henrique Loiola Ponte, Alencar, Nylane Maria Nunes, Silva, Paulo Goberlânio Barros, Alves, Ana Paula Negreiros Nunes, Almeida, Paulo Roberto Carvalho, Cunha, Fernando Queiroz, Lima-Júnior, Roberto César Pereira

“…Ifosfamide (IFO) is an antineoplastic drug that is commonly used to treat gynecological and breast cancers. Hemorrhagic cystitis (HC) is a common side effect…”
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Chemotherapy-associated steatohepatitis induced by irinotecan: a novel animal model by Costa, Marcelo Leite Vieira, Lima-Júnior, Roberto César Pereira, Aragão, Karoline Sabóia, Medeiros, Raul Pinheiro, Marques-Neto, Raphael Dias, de Sá Grassi, Lucas, Leite, Leandro Linhares, Nunes, Lorena Guimaraes, de Mesquita Neto, José Wilson Benevides, de Castro Brito, Gerly Anne, de Souza, Marcellus Henrique Loiola Pontes, de Almeida, Paulo Roberto Carvalho, Ribeiro, Ronaldo Albuquerque

“…Purpose Nonalcoholic steatohepatitis (NASH) has been associated with irinotecan (IRI)-based cancer chemotherapy regimens. The purpose of this study was to…”
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Amitriptyline, clomipramine, and maprotiline attenuate the inflammatory response by inhibiting neutrophil migration and mast cell degranulation by Gurgel, José Alves, Lima-Júnior, Roberto César Pereira, Rabelo, Cristiano Oliveira, Pessoa, Breno Bezerra Gomes Pinho, Brito, Gerly Anne Castro, Ribeiro, Ronaldo Albuquerque

“…Despite the recognized anti-inflammatory potential of heterocyclic antidepressants, the mechanisms concerning their modulating effects are not completely…”
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Paradoxical interaction between cancer and long-term postsepsis disorder: impairment of de novo carcinogenesis versus favoring the growth of established tumors by Leite, Caio Abner, Mota, Jose Mauricio, de Lima, Kalil Alves, Wanderley, Carlos Wagner, Nascimento, Leticia Almeida, Ferreira, Marcela Davoli, Silva, Camila Meirelles Souza, Colon, David Fernando, Sakita, Juliana Yumi, Kannen, Vinicius, Viacava, Paula Ramos, Begnami, Maria Dirlei, Lima-Junior, Roberto Cesar Pereira, Cordeiro de Lima, Vladmir Claudio, Alves-Filho, Jose Carlos, Cunha, Fernando Queiroz, Ribeiro, Ronaldo Albuquerque

“…Previous data have reported that the growth of established tumors may be facilitated by postsepsis disorder through changes in the microenvironment and immune…”
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FLOX (5-fluorouracil + leucovorin + oxaliplatin) chemotherapy for colorectal cancer leads to long-term orofacial neurotoxicity: a STROBE-guided longitudinal prospective study by de Albuquerque Ribeiro Gondinho, Priscilla, de Barros Silva, Paulo Goberlânio, Lisboa, Mário Roberto Pontes, Costa, Bruno Almeida, da Rocha Filho, Duílio Reis, Gifoni, Markus Andret Cavalcante, Lima, Marcos Venicio Alves, Junior, Roberto César Pereira Lima, Vale, Mariana Lima

“…Background Colorectal carcinoma (CRC) is widely treated by chemotherapy based on an intensely neurotoxic drug: oxaliplatin (OXL). We objective to evaluate…”
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Progressive loss of E-cadherin immunoexpression during cervical carcinogenesis by Cavalcante, José Roosevelt, Sampaio, João Paulo Aguiar, Maia Filho, João Tarcísio Alves, Vieira, Renato Braga, Eleutério, Jr, José, Lima, Jr, Roberto César Pereira, Ribeiro, Ronaldo Albuquerque, Almeida, Paulo Roberto Carvalho

“…To investigate E-cadherin immunoexpression during cervical carcinogenesis. We assessed the immunohistochemical expression of E-cadherin in squamous…”
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TLR4 deficiency upregulates TLR9 expression and enhances irinotecan‐related intestinal mucositis and late‐onset diarrhoea by Wong, Deysi Viviana Tenazoa, Holanda, Renata Brito Falcão, Cajado, Aurilene Gomes, Bandeira, Alessandro Maia, Pereira, Jorge Fernando Bessa, Amorim, Joice Oliveira, Torres, Clarice Sampaio, Ferreira, Luana Maria Moura, Lopes, Marina Helena Silva, Oliveira, Roberta Taiane Germano, Pereira, Anamaria Falcão, Sant'Ana, Rosane Oliveira, Arruda, Larissa Mont'alverne, Ribeiro‐Júnior, Howard Lopes, Pinheiro, Ronald Feitosa, Almeida, Paulo Roberto Carvalho, Carvalho, Robson Francisco, Chaves, Fábio Figueiredo, Rocha‐Filho, Duílio Reis, Cunha, Fernando Queiroz, Lima‐Júnior, Roberto César Pereira

“…Background and purpose Severe diarrhoea, a common gastrointestinal manifestation of anticancer treatment with irinotecan, might involve single nucleotide…”
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