Search Results - "Júdice, Wagner Alves de Souza"

Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis by Lourenço, Estela Mariana Guimarães, Di Iório, Juliana Fortes, da Silva, Fernanda, Fialho, Felipe Leonardo Bley, Monteiro, Melquisedeque Mateus, Beatriz, Adilson, Perdomo, Renata Trentin, Barbosa, Euzébio Guimarães, Oses, Jean Pierre, de Arruda, Carla Cardozo Pinto, de Souza Júdice, Wagner Alves, Rafique, Jamal, de Lima, Dênis Pires

“…Leishmaniasis is a neglected tropical disease, affecting more than 350 million people globally. However, there is currently no vaccine available against human…”
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In vitro and in vivo activity of an organic tellurium compound on Leishmania (Leishmania) chagasi by Salerno Pimentel, Isabella Aparecida, Paladi, Carolina de Siqueira, Katz, Simone, de Souza Júdice, Wagner Alves, Cunha, Rodrigo L O R, Barbiéri, Clara Lúcia

“…Tellurium compounds have shown several biological properties and recently the leishmanicidal effect of one organotellurane was demonstrated. These findings led…”
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Low biological phosphorus removal from effluents treated by slow sand filters by Papp, Luiz Antonio, Cardinali-Rezende, Juliana, de Souza Júdice, Wagner Alves, Sanchez, Marília Bixilia, Araújo, Welington Luiz

“…The legislation for environment protection requires strict controls of the wastewater releasing in water bodies. The wastewater treatment plants (WWTP) have…”
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Total phosphorus contents currently found in the raw wastewater – Problems and technical solutions for its removal in full-scale wastewater treatment plants by Papp, Luiz Antonio, Cardinali-Rezende, Juliana, Júdice, Wagner Alves de Souza, Sanches, Marília Bixilia, Araújo, Welington Luiz

“…•Wastewater phosphorus levels is 12 times higher than described in the literature.•Low phosphorus removal due to the low carbon to phosphorus ratio.•The…”
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Oximic compounds as potential inhibitors of metacaspase-2 (TbMCA2) of Trypanosoma brucei by Araujo, Laura Helena, Bueno Chagas, Thaynan Aparecida, Reis, Taiz, de Morais Borba, João Ricardo Bueno, Trujilho, Mariana Nascimento Romero, Dalzoto, Laura de Azevedo Maffeis, Marcondes, Marcelo Ferreira, Juliano, Maria Aparecida, Júdice, Wagner Alves de Souza, Veloso, Márcia Paranho, Machado, Maurício Ferreira Marcondes

“…Metacaspases are a distinct class of cysteine proteases predominantly found in plants, fungi, and protozoa, crucial for regulating programmed cell death (PCD)…”
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In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis by Paladi, Carolina de Siqueira, Pimentel, Isabella Aparecida Salerno, Katz, Simone, Cunha, Rodrigo L O R, Judice, Wagner Alves de Souza, Caires, Antonio C F, Barbiéri, Clara Lúcia

“…Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the…”
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Onsite Wastewater Treatment Upgrade for Water Reuse in Cooling Towers and Toilets by Luiz Antonio Papp, Flávio Aparecido Rodrigues, Wagner Alves de Souza Júdice, Welington Luiz Araújo

“…The increasing population size and housing density are responsible for greater consumption of water resources, causing drinking water shortages in many…”
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4‐Deoxyraputindole C induces cell death and cell cycle arrest in tumor cell lines by Vital, Wagner D., Torquato, Heron F. V., Jesus, Larissa de Oliveira Passos, Judice, Wagner Alves de Souza, Silva, Maria Fátima das G. F. da, Rodrigues, Tiago, Justo, Giselle Zenker, Veiga, Thiago A. M., Paredes‐Gamero, Edgar J.

“…Several molecules extracted from natural products exhibit different biological activities, such as ion channel modulation, activation of signaling pathways,…”
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Semysinthetic biflavonoid Morelloflavone-7,4′,7″,3‴,4‴-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kexin PC1/3 than Kex2 and Furin by de Souza, Aline Aparecida, de Andrade, Débora Martins, Siqueira, Fábio da Silva, Di Iorio, Juliana Fortes, Veloso, Marcia Paranho, Coelho, Camila de Morais, Viegas Junior, Claudio, Gontijo, Vanessa Silva, dos Santos, Marcelo Henrique, Meneghetti, Maria Cecília Zorél, Nader, Helena Bonciani, Tersariol, Ivarne Luis dos Santos, Juliano, Luiz, Juliano, Maria Aparecida, Judice, Wagner Alves de Souza

“…Garcinia brasiliensis is a species native to the Amazon forest. The white mucilaginous pulp is used in folk medicine as a wound healing agent and for peptic…”
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In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblastic Leukemia Models by Jesus, Larissa de Oliveira Passos, de Souza, Aline Aparecida, Torquato, Heron Fernandes Vieira, Gontijo, Vanessa Silva, Pereira de Freitas, Rossimirian, Gesteira, Tarsis Ferreira, Coulson-Thomas, Vivien Jane, Torquato, Ricardo José Soares, Tanaka, Aparecida Sadae, Paredes-Gamero, Edgar Julian, Judice, Wagner Alves de Souza

“…This study investigates the efficacy of miltefosine, alkylphospholipid, and alkyltriazolederivative compounds against leukemia lineages. The cytotoxic effects…”
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Specificity characterization of the α-mating factor hormone by Kex2 protease by Manfredi, Marcella Araújo, Antunes, Alyne Alexandrino, Jesus, Larissa de Oliveira Passos, Juliano, Maria Aparecida, Juliano, Luiz, Judice, Wagner Alves de Souza

“…Kex2 is a Ca2+-dependent serine protease from S. cerevisiae. Characterization of the substrate specificity of Kex2 is of particular interest because this…”
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Benzophenone derivatives as cysteine protease inhibitors and biological activity against Leishmania(L.) amazonensis amastigotes by de Almeida, Letícia, Alves, Karina Ferreira, Maciel-Rezende, Claudia Mara, Jesus, Larissa de Oliveira Passos, Pires, Francieli Ribeiro, Junior, Claudio Viegas, Izidoro, Mario Augusto, Júdice, Wagner Alves de Souza, dos Santos, Marcelo Henrique, Marques, Marcos José

“…Abstract The leishmanicidal potential of benzophenones has been described, some of them highlighting their potential as cysteine protease inhibitors…”
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Thermodynamic analysis of Kex2 activity: The acylation and deacylation steps are potassium- and substrate-dependent by Antunes, Alyne Alexandrino, Jesus, Larissa de Oliveira Passos, Manfredi, Marcella Araújo, de Souza, Aline Aparecida, Machado, Maurício Ferreira Marcondes, e Silva, Pamela Moraes, Icimoto, Marcelo Yudi, Juliano, Maria Aparecida, Juliano, Luiz, Judice, Wagner Alves de Souza

“…Kex2 is the prototype of a large family of eukaryotic subtilisin-related proprotein-processing proteases that cleave at sites containing pairs of basic…”
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In Vitro and In Vivo Activity of an Organic Tellurium Compound on Leishmania by Pimentel, Isabella Aparecida Salerno, Paladi, Carolina de Siqueira, Katz, Simone, Júdice, Wagner Alves de Souza, Cunha, Rodrigo L. O. R, Barbiéri, Clara Lúcia

“…Tellurium compounds have shown several biological properties and recently the leishmanicidal effect of one organotellurane was demonstrated. These findings led…”
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Metacaspase of Saccharomyces cerevisiae (ScMCA-Ia) presents different catalytic cysteine in a processed and non-processed form by Dalzoto, Laura de Azevedo Maffeis, Trujilho, Mariana Nascimento Romero, Santos, Taiz Dos Reis, Costa, João Pedro Martins Silva, Duarte, Ane Caroline Moreira, Judice, Wagner Alves de Souza, Marcondes, Marcelo Ferreira, Machado, Maurício Ferreira Marcondes

“…Metacaspases are cysteine proteases belonging to the CD clan of the C14 family. They possess important characteristics, such as specificity for cleavage after…”
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Leishmanicidal, antiproteolytic, and mutagenic evaluation of alkyltriazoles and alkylphosphocholines by Gontijo, Vanessa Silva, Espuri, Patrícia Ferreira, Alves, Rosemeire Brondi, de Camargos, Luiz Fernando, Santos, Fábio Vieira dos, de Souza Judice, Wagner Alves, Marques, Marcos José, Freitas, Rossimiriam Pereira

“…A series of 16 simple long-chain alkyltriazoles and two novel alkylphosphocholine derivatives containing an azide moiety were evaluated in vitro for their…”
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Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides to define substrate specificity of carboxydipeptidases: assays with human cathepsin B by Cotrin, Simone Silva, Puzer, Luciano, de Souza Judice, Wagner Alves, Juliano, Luiz, Carmona, Adriana K., Juliano, Maria Aparecida

“…We have developed positional scanning synthetic combinatorial libraries to define the substrate specificity of carboxydipeptidases. The library…”
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Morelloflavone and its semisynthetic derivatives as potential novel inhibitors of cysteine and serine proteases by Vanessa, Silva Gontijo, Jaqueline, Pereira Januario, Wagner, Alves de Souza Judice, Alyne, Alexandrino Antunes, Ingridy, Ribeiro Cabral, Diego, Magno Assis, Maria, Aparecida Juliano, Ihosvany, Camps, Marcos, Jose Marques, Claudio, Viegas Junior, Marcelo, Henrique dos Santos

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