Search Results - "Jørgensen, Astrid Sissel"

Dendritic Cells and CCR7 Expression: An Important Factor for Autoimmune Diseases, Chronic Inflammation, and Cancer by Brandum, Emma Probst, Jørgensen, Astrid Sissel, Rosenkilde, Mette Marie, Hjortø, Gertrud Malene

“…Chemotactic cytokines—chemokines—control immune cell migration in the process of initiation and resolution of inflammatory conditions as part of the body’s…”
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Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4 by Berg, Christian, Daugvilaite, Viktorija, Steen, Anne, Jørgensen, Astrid Sissel, Våbenø, Jon, Rosenkilde, Mette Marie

“…CXC chemokine receptor 4 (CXCR4) is involved in multiple physiological and pathological processes, notably as a coreceptor for human immunodeficiency virus…”
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Biased signaling of G protein-coupled receptors – From a chemokine receptor CCR7 perspective by Jørgensen, Astrid Sissel, Rosenkilde, Mette M., Hjortø, Gertrud M.

“…•Biased signaling of GPCR CCR7 controlling immune cell migration and behavior.•Receptor structural rearrangements responsible for directing GPCR bias.•In vivo…”
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Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails by Brandum, Emma Probst, Jørgensen, Astrid Sissel, Calvo, Marina Barrio, Spiess, Katja, Peterson, Francis C, Yang, Zhang, Volkman, Brian F, Veldkamp, Christopher T, Rosenkilde, Mette Marie, Goth, Christoffer Knak, Hjortø, Gertrud Malene

“…The chemokine receptor CCR7 and its ligands CCL19 and CCL21 regulate the lymph node homing of dendritic cells and naïve T-cells and the following induction of…”
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The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus by Jørgensen, Astrid Sissel, Brandum, Emma Probst, Mikkelsen, Jeppe Malthe, Orfin, Klaudia A., Boilesen, Ditte Rahbæk, Egerod, Kristoffer Lihme, Moussouras, Natasha A., Vilhardt, Frederik, Kalinski, Pawel, Basse, Per, Chen, Yen-Hsi, Yang, Zhang, Dwinell, Michael B., Volkman, Brian F., Veldkamp, Christopher T., Holst, Peter Johannes, Lahl, Katharina, Goth, Christoffer Knak, Rosenkilde, Mette Marie, Hjortø, Gertrud Malene

“…The endogenous chemokines CCL19 and CCL21 signal via their common receptor CCR7. CCL21 is the main lymph node homing chemokine, but a weak chemo-attractant…”
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