Search Results - "Jørgensen, A.L."

The molecular genetics of chemotherapy–induced peripheral neuropathy: A systematic review and meta-analysis by Cliff, J., Jorgensen, A.L., Lord, R., Azam, F., Cossar, L., Carr, D.F., Pirmohamed, M.

“…•Evidence for genetic variants associated with CIPN is currently inconclusive.•Several SNPs are of interest and warrant further study.•Clear and consistent…”
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Piglets born from handmade cloning, an innovative cloning method without micromanipulation by Du, Y., Kragh, P.M., Zhang, Y., Li, J., Schmidt, M., Bøgh, I.B., Zhang, X., Purup, S., Jørgensen, A.L., Pedersen, A.M., Villemoes, K., Yang, H., Bolund, L., Vajta, G.

“…Porcine handmade cloning (HMC), a simplified alternative of micromanipulation based traditional cloning (TC) has been developed in multiple phases during the…”
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Biomarker-guided trials: challenges in practice by M, Antoniou, Kolamunnage-Dona, R., J, Wason, R, Bathia, C, Billingham, JM, Bliss, LC, Brown, A, Gillman, J, Paul, AL, Jorgensen

“…Biomarker-guided trials have drawn considerable attention as they promise to lead to improvements in the benefit-risk ratio of treatments and enhanced…”
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Cervical Stitch (Cerclage) For Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis by Jorgensen, A.L, Alfirevic, Z, Tudur Smith, C, Williamson, P.R

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药物引发的史蒂文斯‐约翰逊综合征/中毒性表皮坏死松解症患者血清及水泡液中高迁移率族蛋白 B 的蛋白含量高迁移率族 by Carr, D.F., Wang, C.‐W., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., Bergfeld, W., Jorgensen, A.L., Chung, W.‐H., Pirmohamed, M.

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Serum and blister‐fluid elevation and decreased epidermal content of high‐mobility group box 1 protein in drug‐induced Stevens–Johnson syndrome/toxic epidermal necrolysis by Carr, D.F., Wang, C.‐W., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., Bergfeld, W., Jorgensen, A.L., Chung, W.‐H., Pirmohamed, M.

“…Summary Background High‐mobility group box 1 (HMGB1) is a damage‐associated molecular‐pattern protein. Stevens–Johnson syndrome (SJS)/toxic epidermal…”
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Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing by Lenzini, P, Wadelius, M, Kimmel, S, Anderson, J L, Jorgensen, A L, Pirmohamed, M, Caldwell, M D, Limdi, N, Burmester, J K, Dowd, M B, Angchaisuksiri, P, Bass, A R, Chen, J, Eriksson, N, Rane, A, Lindh, J D, Carlquist, J F, Horne, B D, Grice, G, Milligan, P E, Eby, C, Shin, J, Kim, H, Kurnik, D, Stein, C M, McMillin, G, Pendleton, R C, Berg, R L, Deloukas, P, Gage, B F

“…Well‐characterized genes that affect warfarin metabolism (cytochrome P450 (CYP) 2C9) and sensitivity (vitamin K epoxide reductase complex 1 (VKORC1)) explain…”
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HMGB1 expression in SJS/TEN sera and skin by Carr, D.F., Wang, C.‐W., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., Bergfeld, W., Jorgensen, A.L., Chung, W.‐H., Pirmohamed, M.

“…Summary Stevens Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, severe, skin blistering conditions in which areas of skin die and detach…”
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A candidate gene study for oxaliplatin induced chronic peripheral neuropathy (OICPN) based on a prior genome wide association study (GWAS) by Cliff, J.R., Carr, D.F., Lord, R.H., Jorgensen, A.L., Pirmohamed, M.

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药物引发的史蒂文斯‐约翰逊综合征/中毒性表皮坏死松解症患者血清及水泡液中高迁移率族蛋白 B 的蛋白含量高迁移率族 by Carr, D.F., Wang, C.‐W., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., Bergfeld, W., Jorgensen, A.L., Chung, W.‐H., Pirmohamed, M.

“…Summary 史蒂文斯‐约翰逊综合征 (SJS) 和中毒性表皮坏死松解症 (TEN) 是一种罕见的、严重的、皮肤起泡的疾病,其中皮肤的某些部位会死亡和脱落。它们实际上代表着严重程度不同的同一种疾病:SJS 患者的体表脱皮面积低于 10%,而 TEN 患者超过 30%。 在英国,每年约有 500…”
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753 The intracellular fate of apolipoprotein E is tau-dependent and APOE allele-specific by Jørgensen, A.L., Anderton, B.H., Hartley, K., Jensen, T.G., Lovestone, S.

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47 Familial Alzheimer's disease co-segregates with a MET146ILE substitution in presenilin-1 by Jørgensen, P., Bus, C., Pallisgaard, N., Bryder, M., Jørgensen, A.L.

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PO-027 Potential use of BH3 mimetics in the treatment of head and neck cancer by Carter, RJ, Butterworth, M, Risk, JM, Jorgensen, AL, Sacco, JJ, Schache, AG, Shaw, RJ, Jones, TM, Cohen, GM, Varadarajan, S

“…IntroductionHead and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. The limited success and significant toxicities associated…”
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Coregulation of FANCA and BRCA1 in human cells by Haitjema, Anneke, Mol, Berber M, Kooi, Irsan E, Massink, Maarten PG, Jørgensen, Jens AL, Rockx, Davy AP, Rooimans, Martin A, de Winter, Johan P, Meijers-Heijboer, Hanne, Joenje, Hans, Dorsman, Josephine C

“…Fanconi anemia (FA) is a genetically heterogeneous syndrome associated with increased cancer predisposition. The underlying genes govern the FA pathway which…”
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Higher rate of evolution of X chromosome alpha‐repeat DNA in human than in the great apes by Laursen, H.B., Jørgensen, A.L., Jones, C., Bak, A.L.

“…The rate of introduction of neutral mutations is lower in man than in other primates, including the chimpanzee. This species is generally regarded as our…”
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Breakpoints in Robertsonian translocations are localized to satellite III DNA by fluorescence in situ hybridization by Gravholt, C H, Friedrich, U, Caprani, M, Jørgensen, A L

“…We characterized 21 t(13;14) and 3 t(14;21) Robertsonian translocations for the presence of DNA derived from the short arms of the translocated acrocentric…”
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