Search Results - "Jørgensen, A L"

Piglets born from handmade cloning, an innovative cloning method without micromanipulation by Du, Y., Kragh, P.M., Zhang, Y., Li, J., Schmidt, M., Bøgh, I.B., Zhang, X., Purup, S., Jørgensen, A.L., Pedersen, A.M., Villemoes, K., Yang, H., Bolund, L., Vajta, G.

“…Porcine handmade cloning (HMC), a simplified alternative of micromanipulation based traditional cloning (TC) has been developed in multiple phases during the…”
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Efficiency of Two Enucleation Methods Connected to Handmade Cloning to Produce Transgenic Porcine Embryos by Li, J, Villemoes, K, Zhang, Y, Du, Y, Kragh, PM, Purup, S, Xue, Q, Pedersen, AM, Jørgensen, AL, Jakobsen, JE, Bolund, L, Yang, H, Vajta, G

“…The purpose of our work was to establish an efficient-oriented enucleation method to produce transgenic embryos with handmade cloning (HMC). After 41-42 h…”
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HLA Genotype and Carbamazepine-Induced Cutaneous Adverse Drug Reactions: A Systematic Review by Yip, V L, Marson, A G, Jorgensen, A L, Pirmohamed, M, Alfirevic, A

“…Carbamazepine (CBZ) therapy is associated with cutaneous adverse reactions in up to 10% of patients. Predisposition to these hypersensitivity reactions has…”
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SLCO1B1 Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink by Carr, D F, O'Meara, H, Jorgensen, A L, Campbell, J, Hobbs, M, McCann, G, van Staa, T, Pirmohamed, M

“…This study aimed to determine whether patients with statin‐induced myopathy could be identified using the United Kingdom Clinical Practice Research Datalink,…”
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Serum and blister‐fluid elevation and decreased epidermal content of high‐mobility group box 1 protein in drug‐induced Stevens–Johnson syndrome/toxic epidermal necrolysis by Carr, D.F., Wang, C.‐W., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., Bergfeld, W., Jorgensen, A.L., Chung, W.‐H., Pirmohamed, M.

“…Summary Background High‐mobility group box 1 (HMGB1) is a damage‐associated molecular‐pattern protein. Stevens–Johnson syndrome (SJS)/toxic epidermal…”
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Biomarker-guided trials: challenges in practice by M, Antoniou, Kolamunnage-Dona, R., J, Wason, R, Bathia, C, Billingham, JM, Bliss, LC, Brown, A, Gillman, J, Paul, AL, Jorgensen

“…Biomarker-guided trials have drawn considerable attention as they promise to lead to improvements in the benefit-risk ratio of treatments and enhanced…”
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Cervical stitch (cerclage) for preventing pregnancy loss : individual patient data meta-analysis by JORGENSEN, A. L, ALFIREVIC, Z., TUDUR SMITH, C, WILLIAMSON, P. R

“…Several observational studies have claimed high success rates for cerclage in women with cervical insufficiency. A recent Cochrane review found no conclusive…”
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Proteomic and peptidomic study of proteolysis in quarter milk after infusion with lipoteichoic acid from Staphylococcus aureus by Larsen, L B, Hinz, K, Jørgensen, A L W, Møller, H S, Wellnitz, O, Bruckmaier, R M, Kelly, A L

“…Mastitic milk is associated with increased bovine protease activity, such as that from plasmin and somatic cell enzymes, which cause proteolysis of the caseins…”
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Different patterns of X inactivation in MZ twins discordant for red-green color-vision deficiency by JØRGENSEN, A. L, PHILIP, J, RASKIND, W. H, MATSUSHITA, M, CHRISTENSEN, B, DREYER, V, MOTULSKY, A. G

“…Two female identical twins who were clinically normal were obligatory heterozygotes for X-linked deuteranomaly associated with a green-red fusion gene derived…”
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The cycling of nitrogen in the Danish agricultural sector and the loss to the environment by Jorgensen, LA

“…The total nitrogen flow through the Danish agricultural sector can be obtained from surveys conducted using traditional national statistical methods. These…”
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A new mechanism in blue cone monochromatism by LADEKJAER-MIKKELSEN, A.-S, ROSENBERG, T, JØRGENSEN, A. L

“…Blue cone monochromatism (BCM) is a rare X-linked colour vision disorder characterized by the absence of both red and green cone sensitivity. Most mutations…”
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Homologous Subfamilies of Human Alphoid Repetitive DNA on Different Nucleolus Organizing Chromosomes by Jørgensen, Arne Lund, Bostock, Christopher J., Bak, Arne Leth

“…The organization of alphoid repeated sequences on human nucleolus-organizing (NOR) chromosomes 13, 21, and 22 has been investigated. Analysis of hybridization…”
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Creutzfeldt-Jakob disease segregating in a three generation Danish family by Holm, I. E., Bojsen-Møller, K., Nielsen, A. L., JØrgensen, A. L.

“…A three generation family is presented in which rapidly progressive, early‐onset Creutzfeldt–Jakob disease without typical EEG changes segregates as an…”
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A presenilin-1 Thr116Asn substitution in a family with early-onset Alzheimerʼs disease by Romero, Ignacio, Jørgensen, Poul, Bolwig, Gert, Fraser, Paul E, Rogaeva, Ekaterina, Mann, David, Havsager, Anne-Mette, Jørgensen, Arne Lund

“…MUTATION in the presenilin-1 (PS-1) gene at chromosome 14q24.3 is the most common cause of autosomal dominant early-onset Alzheimerʼs disease. Here, we report…”
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Budesonide/formoterol adjustable maintenance dosing reduces asthma exacerbations versus fixed dosing by Ställberg, B, Olsson, P, Jörgensen, L A, Lindarck, N, Ekström, T

“…A guided, adjustable-dosing regimen with budesonide/formoterol was investigated in asthma patients. In a randomised, open, multicentre study, 1034 patients…”
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NAT2 variants and toxicity related to anti-tuberculosis agents: a systematic review and meta-analysis by Richardson, M., Kirkham, J., Dwan, K., Sloan, D. J., Davies, G., Jorgensen, A. L.

“…BACKGROUND: Tuberculosis (TB) patients receiving anti-tuberculosis treatment may experience serious adverse drug reactions (ADRs) such as hepatotoxicity…”
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The molecular genetics of chemotherapy–induced peripheral neuropathy: A systematic review and meta-analysis by Cliff, J., Jorgensen, A.L., Lord, R., Azam, F., Cossar, L., Carr, D.F., Pirmohamed, M.

“…•Evidence for genetic variants associated with CIPN is currently inconclusive.•Several SNPs are of interest and warrant further study.•Clear and consistent…”
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Clinical predictors of active LN development in children – evidence from the UK JSLE Cohort Study by Smith, E M D, Yin, P, Jorgensen, A L, Beresford, M W

“…Background Juvenile-onset systemic lupus erythematosus (JSLE) patients may develop lupus nephritis (LN) during their initial presentation, or later in their…”
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Growing international evidence for urinary biomarker panels identifying lupus nephritis in children – verification within the South African Paediatric Lupus Cohort by Smith, E M D, Lewandowski, L B, Jorgensen, A L, Phuti, A, Nourse, P, Scott, C, Beresford, M W

“…Background A urinary biomarker panel including alpha-1-acid-glycoprotein (AGP), lipocalin-like-prostaglandin-D-synthase (LPGDS), transferrin and ceruloplasmin…”
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Do classic blood biomarkers of JSLE identify active lupus nephritis? Evidence from the UK JSLE Cohort Study by Smith, E M D, Jorgensen, A L, Beresford, M W

“…Background Lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus erythematosus (JSLE) patients. The value of commonly available biomarkers,…”
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