Search Results - "Jöchen, K."

Food Addiction, High-Glycemic-Index Carbohydrates, and Obesity by Lennerz, Belinda, Lennerz, Jochen K

“…Treatment success in obesity remains low, and recently food addiction has been delineated as an underlying etiologic factor with therapeutic relevance…”
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Origins of lymphatic and distant metastases in human colorectal cancer by Naxerova, Kamila, Reiter, Johannes G., Brachtel, Elena, Lennerz, Jochen K., van de Wetering, Marc, Rowan, Andrew, Cai, Tianxi, Clevers, Hans, Swanton, Charles, Nowak, Martin A., Elledge, Stephen J., Jain, Rakesh K.

“…The spread of cancer cells from primary tumors to regional lymph nodes is often associated with reduced survival. One prevailing model to explain this…”
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Breath gas aldehydes as biomarkers of lung cancer by Fuchs, Patricia, Loeseken, Christian, Schubert, Jochen K., Miekisch, Wolfram

“…There is experimental evidence that volatile substances in human breath can reflect presence of neoplasma. Volatile aldehydes were determined in exhaled breath…”
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A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity by Colonna, Marco, Cella, Marina, Fuchs, Anja, Vermi, William, Facchetti, Fabio, Otero, Karel, Lennerz, Jochen K. M, Doherty, Jason M, Mills, Jason C

“…Natural killer (NK) cells are classically viewed as lymphocytes that provide innate surveillance against virally infected cells and tumour cells through the…”
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Elastic properties of polycrystalline microcomponents by Böhlke, T., Jöchen, K., Kraft, O., Löhe, D., Schulze, V.

“…The statistics of Young’s modulus of microspecimens subjected to a tensile load is examined experimentally, numerically and analytically. The material…”
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Dimensions of health data Integrity by Lennerz, Jochen K., Schneider, Nick, Lauterbach, Karl

“…Health data integrity, as an emergent concept, stands to reshape the lifecycle of data-driven healthcare and research, ensuring a shared commitment to ethical…”
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Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice by ten Brinke, Michiel M., Boele, Henk-Jan, Spanke, Jochen K., Potters, Jan-Willem, Kornysheva, Katja, Wulff, Peer, IJpelaar, Anna C.H.G., Koekkoek, Sebastiaan K.E., De Zeeuw, Chris I.

“…Three decades of electrophysiological research on cerebellar cortical activity underlying Pavlovian conditioning have expanded our understanding of motor…”
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COVID-19-neutralizing antibodies predict disease severity and survival by Garcia-Beltran, Wilfredo F., Lam, Evan C., Astudillo, Michael G., Yang, Diane, Miller, Tyler E., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Clayton, Kiera L., Nitido, Adam D., Murali, Mandakolathur R., Alter, Galit, Charles, Richelle C., Dighe, Anand, Branda, John A., Lennerz, Jochen K., Lingwood, Daniel, Schmidt, Aaron G., Iafrate, A. John, Balazs, Alejandro B.

“…Coronavirus disease 2019 (COVID-19) exhibits variable symptom severity ranging from asymptomatic to life-threatening, yet the relationship between severity and…”
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Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer by Yoda, Satoshi, Lin, Jessica J, Lawrence, Michael S, Burke, Benjamin J, Friboulet, Luc, Langenbucher, Adam, Dardaei, Leila, Prutisto-Chang, Kylie, Dagogo-Jack, Ibiayi, Timofeevski, Sergei, Hubbeling, Harper, Gainor, Justin F, Ferris, Lorin A, Riley, Amanda K, Kattermann, Krystina E, Timonina, Daria, Heist, Rebecca S, Iafrate, A John, Benes, Cyril H, Lennerz, Jochen K, Mino-Kenudson, Mari, Engelman, Jeffrey A, Johnson, Ted W, Hata, Aaron N, Shaw, Alice T

“…The cornerstone of treatment for advanced ALK-positive lung cancer is sequential therapy with increasingly potent and selective ALK inhibitors. The…”
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MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer by Dagogo-Jack, Ibiayi, Yoda, Satoshi, Lennerz, Jochen K, Langenbucher, Adam, Lin, Jessica J, Rooney, Marguerite M, Prutisto-Chang, Kylie, Oh, Audris, Adams, Nathaniel A, Yeap, Beow Y, Chin, Emily, Do, Andrew, Marble, Hetal D, Stevens, Sara E, Digumarthy, Subba R, Saxena, Ashish, Nagy, Rebecca J, Benes, Cyril H, Azzoli, Christopher G, Lawrence, Michael S, Gainor, Justin F, Shaw, Alice T, Hata, Aaron N

“…Most -positive lung cancers will develop ALK-independent resistance after treatment with next-generation ALK inhibitors. amplification has been described in…”
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Clinicopathologic Characteristics of BRG1-Deficient NSCLC by Dagogo-Jack, Ibiayi, Schrock, Alexa B, Kem, Marina, Jessop, Nicholas, Lee, Jessica, Ali, Siraj M, Ross, Jeffrey S, Lennerz, Jochen K, Shaw, Alice T, Mino-Kenudson, Mari

“…Ten percent of NSCLCs harbor mutations in SMARCA4, the gene encoding the SWItch/Sucrose Non-Fermentable ATPase BRG1. In preclinical models, BRG1 inactivation…”
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Effects of COVID-19 protective face masks and wearing durations on respiratory haemodynamic physiology and exhaled breath constituents by Sukul, Pritam, Bartels, Julia, Fuchs, Patricia, Trefz, Phillip, Remy, Rasmus, Rührmund, Leo, Kamysek, Svend, Schubert, Jochen K., Miekisch, Wolfram

“…Background While assumed to protect against coronavirus transmission, face masks may have effects on respiratory–haemodynamic parameters. Within this pilot…”
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Surface Tension and Density of Pure Ionic Liquids and Some Binary Mixtures with 1-Propanol and 1-Butanol by Wandschneider, Anna, Lehmann, Jochen K, Heintz, Andreas

“…The pendant drop method has been used for measuring the surface tension of the pure ionic liquids 1-ethyl-3-methylimidazolium…”
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Advanced setup for safe breath sampling and patient monitoring under highly infectious conditions in the clinical environment by Sukul, Pritam, Trefz, Phillip, Schubert, Jochen K., Miekisch, Wolfram

“…Being the proximal matrix, breath offers immediate metabolic outlook of respiratory infections. However, high viral load in exhalations imposes higher…”
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Exhaled volatile substances mirror clinical conditions in pediatric chronic kidney disease by Obermeier, Juliane, Trefz, Phillip, Happ, Josephine, Schubert, Jochen K, Staude, Hagen, Fischer, Dagmar-Christiane, Miekisch, Wolfram

“…Monitoring metabolic adaptation to chronic kidney disease (CKD) early in the time course of the disease is challenging. As a non-invasive technique, analysis…”
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Recent advances in the histological and molecular classification of endometrial stromal neoplasms by Ferreira, Joana, Félix, Ana, Lennerz, Jochen K., Oliva, Esther

“…This review addresses known features and recent developments in the histological, immunohistochemical, and molecular characterization of endometrial stromal…”
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Where is laboratory medicine headed in the next decade? Partnership model for efficient integration and adoption of artificial intelligence into medical laboratories by Carobene, Anna, Cabitza, Federico, Bernardini, Sergio, Gopalan, Raj, Lennerz, Jochen K, Weir, Clare, Cadamuro, Janne

“…The field of artificial intelligence (AI) has grown in the past 10 years. Despite the crucial role of laboratory diagnostics in clinical decision-making, we…”
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BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications by Dias-Santagata, Dora, Lam, Quynh, Vernovsky, Kathy, Vena, Natalie, Lennerz, Jochen K, Borger, Darrell R, Batchelor, Tracy T, Ligon, Keith L, Iafrate, A John, Ligon, Azra H, Louis, David N, Santagata, Sandro

“…Pleomorphic xanthoastrocytoma (PXA) is low-grade glial neoplasm principally affecting children and young adults. Approximately 40% of PXA are reported to recur…”
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Novel gene fusions in secretory carcinoma of the salivary glands: enlarging the ETV6 family by Guilmette, Julie, Dias-Santagata, Dora, Nosé, Vânia, Lennerz, Jochen K, Sadow, Peter M

“…Secretory carcinoma (SC) of the salivary gland is a low-grade malignancy associated with a well-defined clinical, histologic, immunohistochemical, and…”
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The landscape of metastatic progression patterns across major human cancers by Budczies, Jan, von Winterfeld, Moritz, Klauschen, Frederick, Bockmayr, Michael, Lennerz, Jochen K, Denkert, Carsten, Wolf, Thomas, Warth, Arne, Dietel, Manfred, Anagnostopoulos, Ioannis, Weichert, Wilko, Wittschieber, Daniel, Stenzinger, Albrecht

“…The majority of patients with solid malignancies die from metastatic burden. However, our current understanding of the mechanisms and resulting patterns of…”
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