Search Results - "Jézéquel, Julie"
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Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients
Published in Nature communications (27-11-2017)“…The identification of circulating autoantibodies against neuronal receptors in neuropsychiatric disorders has fostered new conceptual and clinical frameworks…”
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Cell- and Single Molecule-Based Methods to Detect Anti-N-Methyl-D-Aspartate Receptor Autoantibodies in Patients With First-Episode Psychosis From the OPTiMiSE Project
Published in Biological psychiatry (1969) (15-11-2017)“…Circulating autoantibodies against glutamatergic N-methyl-D-aspartate receptor (NMDAR) have been reported in a proportion of patients with psychotic disorders,…”
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Ketamine alleviates NMDA receptor hypofunction through synaptic trapping
Published in Neuron (Cambridge, Mass.) (09-10-2024)“…Activity-dependent modulations of N-methyl-D-aspartate glutamate receptor (NMDAR) trapping at synapses regulate excitatory neurotransmission and shape…”
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Molecular Pathogenicity of Anti-NMDA Receptor Autoantibody From Patients With First-Episode Psychosis
Published in American Journal of Psychiatry (01-04-2018)Get full text
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Tracking single membrane targets of human autoantibodies using single nanoparticle imaging
Published in Journal of neuroscience methods (01-07-2018)“…•An increasing number of neuropsychiatric diseases have been associated with the expression of human autoantibodies directed against neuronal…”
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Alteration of NMDA receptor trafficking as a cellular hallmark of psychosis
Published in Translational psychiatry (30-08-2021)“…A dysfunction of the glutamatergic transmission, especially of the NMDA receptor (NMDAR), constitutes one of the main biological substrate of psychotic…”
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Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits
Published in Science (American Association for the Advancement of Science) (25-01-2019)“…How neuronal connections are established and organized into functional networks determines brain function. In the mammalian cerebral cortex, different classes…”
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Ultradian corticosterone pulses balance glutamatergic transmission and synaptic plasticity
Published in Proceedings of the National Academy of Sciences - PNAS (30-09-2014)“…Significance A pulse of the adrenal hormone corticosterone (CORT) changes hippocampal glutamate transmission for many hours. CORT is normally released in…”
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Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors
Published in Cell death & disease (10-11-2016)“…N -methyl- d -aspartate receptors (NMDARs) are ion channels whose synaptic versus extrasynaptic localization critically influences their functions. This…”
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Specific alteration of NMDA receptor synaptic trafficking by circulating autoantibodies from schizophrenic patients
Published in Neurology, psychiatry, and brain research (01-03-2016)Get full text
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Relationship Between Serum NMDA Receptor Antibodies and Response to Antipsychotic Treatment in First-Episode Psychosis
Published in Biological psychiatry (1969) (01-07-2021)“…When psychosis develops in NMDA receptor (NMDAR) antibody encephalitis, it usually has an acute or subacute onset, and antipsychotic treatment may be…”
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