Search Results - "Jérôme, Hanna"
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New Hosts of The Lassa Virus
Published in Scientific reports (03-05-2016)“…Lassa virus (LASV) causes a deadly haemorrhagic fever in humans, killing several thousand people in West Africa annually. For 40 years, the Natal multimammate…”
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Role of the C terminus of Lassa virus L protein in viral mRNA synthesis
Published in Journal of virology (01-08-2014)“…The N terminus of arenavirus L protein contains an endonuclease presumably involved in "cap snatching." Here, we employed the Lassa virus replicon system to…”
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Production of biologically active recombinant human factor H in Physcomitrella
Published in Plant biotechnology journal (01-04-2011)“…The human complement regulatory serum protein factor H (FH) is a promising future biopharmaceutical. Defects in the gene encoding FH are associated with human…”
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4
Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication
Published in Journal of general virology (01-07-2019)“…Replicon systems are important tools for investigating viral RNA synthesis. We have developed an ambisense minigenome system for Rift Valley fever virus (RVFV)…”
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Widespread human exposure to ledanteviruses in Uganda: A population study
Published in PLoS neglected tropical diseases (08-07-2024)“…Le Dantec virus (LDV), assigned to the species Ledantevirus ledantec, genus Ledantevirus, family Rhabdoviridae has been associated with human disease but has…”
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Improved gastrointestinal profile with diroximel fumarate is associated with a positive impact on quality of life compared with dimethyl fumarate: results from the randomized, double-blind, phase III EVOLVE-MS-2 study
Published in Therapeutic advances in neurological disorders (2021)“…Background: Diroximel fumarate (DRF) is a novel oral fumarate approved for relapsing forms of multiple sclerosis (MS). DRF demonstrated significantly improved…”
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Intentional Drug Poisoning Care in a Physician-manned Emergency Medical Service
Published in Prehospital emergency care (03-04-2015)“…Abstract Objectives. Severely poisoned patients can benefit from intensive and specific treatments. Emergency medical services (EMS) may therefore play a…”
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NATALIZUMAB REDUCES MS RELAPSE RATES IN UK TOP PATIENTS
Published in Journal of neurology, neurosurgery and psychiatry (01-12-2016)“…IntroductionThe Tysabri® Observational Program (TOP) is a 10-year, ongoing, global open-label study in clinical practice settings enrolling natalizumab-treated…”
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NATALIZUMAB FOR RELAPSING-REMITTING MS IN THE UK TOP COHORT
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2014)“…IntroductionThe TYSABRI registered Observational Program (TOP) is a global, open-label study of natalizumab for relapsing-remitting multiple sclerosis (RRMS)…”
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Diroximel Fumarate Demonstrates an Improved Gastrointestinal Tolerability Profile Compared with Dimethyl Fumarate in Patients with Relapsing–Remitting Multiple Sclerosis: Results from the Randomized, Double-Blind, Phase III EVOLVE-MS-2 Study
Published in CNS drugs (01-02-2020)“…Background Diroximel fumarate (DRF) is a novel oral fumarate approved in the USA for relapsing forms of multiple sclerosis. DRF is converted to monomethyl…”
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Effect of dimethyl fumarate on lymphocytes in RRMS: Implications for clinical practice
Published in Neurology (09-04-2019)“…OBJECTIVETo assess functional changes in lymphocyte repertoire and subsequent clinical implications during delayed-release dimethyl fumarate (DMF) treatment in…”
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Metagenomic next-generation sequencing aids the diagnosis of viral infections in febrile returning travellers
Published in The Journal of infection (01-10-2019)“…•Next generation sequencing (NGS) has potential as an all-in-one diagnostic test for infection.•Viral, bacterial and parasite genomes can be detected…”
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Interim Safety and Efficacy Outcomes in Patients With Relapsing-Remitting Multiple Sclerosis who Received Diroximel Fumarate for Up to 2 Years (2228)
Published in Neurology (13-04-2021)“…Abstract only…”
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Effects of Diroximel Fumarate on Brain Volume Change and Disability Progression in Adults With Relapsing-Remitting Multiple Sclerosis From EVOLVE-MS-1 (1262)
Published in Neurology (13-04-2021)“…Abstract only…”
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Improving the Gastrointestinal Tolerability of Fumaric Acid Esters: Early Findings on Gastrointestinal Events with Diroximel Fumarate in Patients with Relapsing-Remitting Multiple Sclerosis from the Phase 3, Open-Label EVOLVE-MS-1 Study
Published in Advances in therapy (01-11-2019)“…Introduction Diroximel fumarate (DRF) is a novel oral fumarate in development for patients with relapsing forms of multiple sclerosis (MS). Clinical findings…”
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Diroximel fumarate (DRF) in patients with relapsing–remitting multiple sclerosis: Interim safety and efficacy results from the phase 3 EVOLVE-MS-1 study
Published in Multiple sclerosis (01-11-2020)“…Background: Diroximel fumarate (DRF) is a novel oral fumarate for patients with relapsing–remitting multiple sclerosis (RRMS). DRF and the approved drug…”
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Clinical Trial and Post-marketing Reports Indicate No Increased Risk of Herpes Zoster in Patients Treated With Delayed-release Dimethyl Fumarate (P5.362)
Published in Neurology (10-04-2018)“…Abstract only…”
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Efficacy of Delayed-Release Dimethyl Fumarate in Newly Diagnosed and Other Early Multiple Sclerosis Patients, and Patients Switching from Interferon or Glatiramer Acetate, in Routine Medical Practice: Interim Results from ESTEEM (P1.367)
Published in Neurology (10-04-2018)“…Abstract only…”
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053 Pregnancy outcomes with delayed-release dimethyl fumarate: interim results from an international registry
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2018)“…IntroductionClinical trials and post marketing reports show no safety signals with delayed-release dimethyl fumarate (DMF) exposure during pregnancy; however,…”
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Pregnancy Outcomes From an International Registry of Patients Treated With Delayed-release Dimethyl Fumarate (P4.2-095)
Published in Neurology (09-04-2019)“…Abstract only…”
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